Accuracy analysis of intrahepatic fat density measurements using dual-energy computed tomography: Validation using a test phantom

2017 ◽  
Vol 25 (3) ◽  
pp. 403-415 ◽  
Author(s):  
Tomohiro Arai ◽  
Masaki Misawa ◽  
Miki Arai ◽  
Masafumi Shinozaki ◽  
Kayo Sakamoto ◽  
...  
2018 ◽  
Vol 48 (12) ◽  
pp. 1008-1019 ◽  
Author(s):  
Keitaro Sofue ◽  
Masakatsu Tsurusaki ◽  
Achille Mileto ◽  
Tomoko Hyodo ◽  
Kosuke Sasaki ◽  
...  

2021 ◽  
pp. 197140092110474
Author(s):  
Ritwik Chakrabarti ◽  
Vivek Gupta ◽  
Sameer Vyas ◽  
Kirti Gupta ◽  
Vikram Singh

Objective To correlate dual energy computed tomography electron density measurements with histopathological cerebral glioma grading to determine whether it can be used as a non-invasive predictor of cerebral glioma grade. Materials and methods Fifty patients with suspected cerebral gliomas on imaging scheduled to undergo resection were included. We tested our hypothesis that with increasing glioma grade, increased tumor cellularity should translate into increased electron density and if a statistically significant difference between electron density of low-grade gliomas and high-grade gliomas is seen, we may have a clinical use of dual energy computed tomography as a non-invasive tool to predict cerebral glioma grade. A pre-operative dual energy computed tomography scan of the brain was performed, and electron density measurements calculated from the solid part of the tumor. Obtaining a ratio with electron density of contralateral normal brain parenchyma normalized these values. The minimum, maximum and mean electron density and their normalized values recorded between high-grade gliomas and low-grade gliomas were compared for presence of statistical significance. Results A statistically significant difference was found between all six parameters recorded (minimum electron density and normalized values, mean electron density and normalized values, maximum electron density and normalized values) between low-grade gliomas and high-grade gliomas. The predictivity ranged from 75% (for minimum electron density and maximum normalized values) to 81.25% (for mean normalized values). All six parameters were found to have statistically significant positive correlation with Ki-67 index. Conclusion Dual energy computed tomography electron density measurements in cerebral gliomas are predictive of pre-operative differentiation of low-grade gliomas from high-grade gliomas and show a linear, statistically significant positive correlation with Ki-67 index.


2019 ◽  
Author(s):  
Torsten Diekhoff ◽  
Michael Fuchs ◽  
Nils Engelhard ◽  
Kay-Geert Hermann ◽  
Michael Putzier ◽  
...  

2011 ◽  
Vol 12 (1) ◽  
pp. 62-63 ◽  
Author(s):  
Thomas Henzler ◽  
Steffen Diehl ◽  
Susanne Jochum ◽  
Tim Sueselbeck ◽  
Stefan O Schoenberg ◽  
...  

Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 161
Author(s):  
Masakatsu Tsurusaki ◽  
Keitaro Sofue ◽  
Masatoshi Hori ◽  
Kosuke Sasaki ◽  
Kazunari Ishii ◽  
...  

Dual-energy computed tomography (DECT) is an imaging technique based on data acquisition at two different energy settings. Recent advances in CT have allowed data acquisitions and simultaneous analyses of X-rays at two energy levels, and have resulted in novel developments in the field of abdominal imaging. The use of low and high X-ray tube voltages in DECT provide fused images that improve the detection of liver tumors owing to the higher contrast-to-noise ratio (CNR) of the tumor compared with the liver. The use of contrast agents in CT scanning improves image quality by enhancing the CNR and signal-to-noise ratio while reducing beam-hardening artifacts. DECT can improve detection and characterization of hepatic abnormalities, including mass lesions. The technique can also be used for the diagnosis of steatosis and iron overload. This article reviews and illustrates the different applications of DECT in liver imaging.


Diagnostics ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 870
Author(s):  
Saif Afat ◽  
Ahmed E. Othman ◽  
Konstantin Nikolaou ◽  
Sebastian Gassenmaier

To evaluate contrast-enhanced dual-energy computed tomography (DECT) chest examinations regarding pulmonary perfusion patterns and pulmonary opacities in patients with confirmed COVID-19 disease. Fourteen patients with 24 DECT examinations performed between April and May 2020 were included in this retrospective study. DECT studies were assessed independently by two radiologists regarding pulmonary perfusion defects, using a Likert scale ranging from 1 to 4. Furthermore, in all imaging studies the extent of pulmonary opacities was quantified using the same rating system as for perfusion defects. The main pulmonary findings were ground glass opacities (GGO) in all 24 examinations and pulmonary consolidations in 22 examinations. The total lung scores after the addition of the scores of the single lobes showed significantly higher values of opacities compared to perfusion defects, with a median of 12 (9–18) for perfusion defects and a median of 17 (15–19) for pulmonary opacities (p = 0.002). Furthermore, mosaic perfusion patterns were found in 19 examinations in areas with and without GGO. Further studies will be necessary to investigate the pathophysiological background of GGO with maintained perfusion compared to GGO with reduced perfusion, especially regarding long-term lung damage and prognosis.


2020 ◽  
Vol 21 ◽  
pp. S85
Author(s):  
V. Rudenko ◽  
N. Serova ◽  
L. Kapanadze ◽  
M. Taratkin ◽  
Z. Okhunov ◽  
...  

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