Imaging of endolymphatic hydrops: A comprehensive update in primary and secondary hydropic ear disease

2021 ◽  
pp. 1-8
Author(s):  
Michael Eliezer ◽  
Arnaud Attyé ◽  
Michel Toupet ◽  
Charlotte Hautefort

BACKGROUND: Since the first description by Hallpike and Cairns, the excess of endolymphatic fluid, also known as endolymphatic hydrops (EH), has been established as being the main biomarker in patients with Menière’s disease. Recently, the concept of primary (PHED) and secondary hydropic ear disease (SHED) has been introduced. PHED corresponded to Menière’s disease while SHED was defined as the presence of EH in patients with pre-existing inner ear disease. OBJECTIVE: In this article, we would like to summarize the methodology of hydrops exploration using MRI and the previously published radiological findings in patients with PHED and SHED. RESULTS: Before the emergence of delayed inner ear MRI, the presence of EH was assumed based on clinical symptoms. However, because of the recent technical developments, inner ear MRI became an important tool in clinical settings for identifying EH in vivo, in patients with PHED and SHED. The presence of EH on MRI is related with the degree of sensorineural hearing loss whether in patients with PHED or SHED. By contrast, in PHED or SHED patients without sensorineural hearing loss, MRI showed no sign of EH. CONCLUSIONS: Thanks to the recent technical developments, inner ear MRI became an important tool in clinical settings for identifying EH in vivo, in patients with PHED and SHED.

2021 ◽  
pp. 35-40
Author(s):  
V. A. Parfenov

Ménière’s disease (MD) is an idiopathic inner ear disease, which is characterized by noise in the ears, periodic attacks of vertigo and the development of sensorineural hearing loss. MD is characterized by endolymphatic hydrops – an increase in the volume of endolymph that fills the membered labyrinth of the inner ear. Currently highlighted subtypes MD. The first subtype meets most often and is characterized by classical manifestations of MD. The second subtype is characterized by the development of sensorineural hearing loss, to which only after a long time are joined by the episodes of dizziness. The third subtype of MD includes family cases of the disease. The fourth and fifth subtypes of MD is observed in patients with migraine and autoimmune diseases. The diagnosis of definite MD is based on the 2 or more spontaneous episodes of vertigo with each lasting 20 minutes to 12 hours, low-to medium-frequency sensorineural hearing loss in one ear, fluctuating aural symptoms (fullness, hearing, tinnitus) located in the affected ear, and lack of data for other reasons for dizziness. There are no effective treatment for auditory disorders MD, therapy is aimed at preventing dizziness attacks. The first line of MD’s therapy includes a dietary salt restriction, the use of betahistine and diuretics. Betahistine (Betaserc) is usually used in a daily dose of 48 mg for 3–6 months to reduce the frequency of vertigo. For long-term treatment, it is convenient to use a betahistine modified-released (Betaserc Long) 48 mg, taken once a day. With the ineffectiveness of conservative therapy, other methods of therapy are possible: intratympanic administration of corticosteroids or gentamicin, labyrinthectomy or vestibular neurectomy. Unfortunately, many patients suffering from BM mistakenly makes a diagnosis of cerebrovascular disease, vertebrobasilar insufficiency, cervical osteochondrosis. Diagnostic errors are usually caused by the fact that the patients with MD are not conducted audiometry, vestibular tests, and the signs of cerebral microangiopathy identified when MRI brain are mistakenly regarded as confirmation of vascular dizziness genesis.


1998 ◽  
Vol 118 (6) ◽  
pp. 747-750 ◽  
Author(s):  
DAVID WOOJIN KIM ◽  
JEFFREY P. HARRIS

OBJECTIVE: The association of various immunologic abnormalities with the presence of silicone breast implants in women has been described. In addition, some studies report a correlation between autoimmune disorders and silicone breast implants, whereas other studies indicate no difference in the incidence of disease between women with silicone breast implants and control groups. Until recently, no reports had attempted to identify an association between silicone breast implants and hearing impairment. A recent study suggested a possible correlation between prior silicone breast implants and the development of various forms of hearing loss. This study tried to determine whether such a correlation could be duplicated. METHODS: To determine whether such a correlation could be established, we studied 119 female patients with either Meniere's disease or progressive sensorineural hearing loss and 100 age-matched healthy controls. Subjects completed questionnaires that provided various types of information, including the presence or absence of previous silicone breast implants. Serum from all 119 patients with Meniere's disease and progressive sensorineural hearing loss had been subjected to previous Western blot testing for reactivity to a 68 kD protein associated with certain forms of autoimmune hearing loss. RESULTS: Results indicated no significant difference in frequency of prior silicone breast implants among the patients with Meniere's disease, patients with sensorineural hearing loss, or controls. The presence or absence of the 68 kD protein also was not significantly relevant to the frequency of silicone breast implants. CONCLUSIONS: Our data did not show evidence of a significant relationship between the presence of silicone breast implants and later development of Meniere's disease, progressive sensorineural hearing loss, or positive 68 kD serum. (Otolaryngol Head Neck Surg 1998;118:747-50.)


2021 ◽  
Vol 11 (5) ◽  
pp. 174-177
Author(s):  
Abdul Nasir ◽  
Minhaj Ahmad ◽  
Zehra Zaidi ◽  
SM Arif Zaidi

Meniere’s disease, also called endolymphatic hydrops, is a disorder of the inner ear where the endolymphatic system is distended due to endolymph. It is characterized by vertigo, Tinnitus, sensorineural hearing loss and aural fullness. The main pathology in Meniere’s disease is distention of endolymphatic system due to increased volume of endolymph. This can result either from increased production of endolymph or its faulty absorption or both. The description of hypothyroidism as a disease is not directly found in Unani texts. However, the signs and symptoms of meniere’s disease such as Dawar (vertigo), Taneen (tinnitus), Hissi Asabi Bahrapan (sensorineural hearing loss), Seqal-e-Uzn (aural fullness) mentioned in unani medicine associated with clinical manifestation in the context of Su-e-Mizaj Barid Maddi (derangement in cold temperament) as a result of an excess production endolymph (Kasrate Ifraz-e-Androon lymph) or defective absorption of endolymph (Nuqse Jazb-e- Androon lymph) in abnormal phlegm in the internal ear. On the basis of this fact, an attempt has been herewith made to understand the disease and its management through Unani Medicine. Keywords: Meniere’s disease, Vertigo, Tinnitus, Taneen, Deafness


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