Influence of fixation on circular vection

2000 ◽  
Vol 10 (3) ◽  
pp. 151-155
Author(s):  
Hiroaki Fushiki ◽  
Satoru Takata ◽  
Yukio Watanabe
Keyword(s):  
Vertical Axis ◽  
Constant Acceleration ◽  
Circular Vection ◽  
Hemispherical Dome ◽  
The Mean ◽  
Fixation Points ◽  
Self Motion ◽  
Random Dot Pattern ◽  
Normal Adults ◽  
Moving Pattern

The contribution of fixation to latency of circular vection (CV) was examined in twenty-five normal adults aged 18–30 years. For induction of self-motion a random dot pattern was projected onto a hemispherical dome. The pattern was rotated either about the subject’s vertical axis or about their interaural axis at a constant acceleration of 1 deg / s 2 . For the group tested, the perceived CV latencies were significantly shorter with fixation than without fixation in both horizontal and vertical CV. The effect of fixation was pronounced in subjects with longer latencies. The mean CV latencies for two different fixation points between the subject’s eyes and the moving pattern did not differ significantly. Our results suggest that the potential influence of fixation must be carefully controlled in studies of visually induced self-motion. Possible explanations for the effect of fixation on the generation of CV will also be discussed.

Directional preponderance in pitch circular vection

2000 ◽  
Vol 10 (2) ◽  
pp. 93-98
Author(s):  
H. Fushiki ◽  
S. Takata ◽  
K. Yasuda ◽  
Y. Watanabe
Keyword(s):  
Stimulus Presentation ◽  
Vertical Axis ◽  
Directional Asymmetry ◽  
Stripe Pattern ◽  
Circular Vection ◽  
Significant Difference ◽  
Perception Of Self ◽  
Self Motion ◽  
Random Dot Pattern ◽  
Rotational Stimulation

We used optokinetic stimulation (OKS) in eighteen normal adults aged 18–30 years to investigate vertical self-motion perception. In order to induce self-rotation, either a stripe pattern or a random dot pattern was projected onto the inner wall of a hemispherical dome with a diameter of 150 cm. The pattern was rotated either about the subject’s vertical axis (yaw) or about the subject’s interaural axis (pitch) for 80 s at a constant acceleration of 1 deg / s 2 . Stimuli were randomly repeated three to four times in each direction. The latency of onset as well as the perceived intensity of circular vection (CV) was measured for each stimulus presentation. CV latencies for upward rotational stimulation were significantly longer than those for downward rotational stimulation under both types of stimulus conditions. There was no significant difference in CV latency between rightward and leftward rotational stimulation. For most subjects, the magnitudes of the perceived CV for rightward rotational stimulation were equal to those for leftward rotational stimulation, whereas the magnitudes of the perceived CV for vertical stimulation showed large intersubject variability. These results provide additional evidence that fundamental differences exist between different types of self-motion. Possible explanations for the directional asymmetry in vertical perception of self-motion will also be discussed.

scholarly journals Self-Motion Signals in Vestibular Nuclei Neurons Projecting to the Thalamus in the Alert Squirrel Monkey

2009 ◽  
Vol 101 (4) ◽  
pp. 1730-1741 ◽  
Author(s):  
Vladimir Marlinski ◽  
Robert A. McCrea
Keyword(s):  
Electrical Stimulation ◽  
Vertical Axis ◽  
Vestibular Nuclei ◽  
Head Movements ◽  
Stimulus Velocity ◽  
The Earth ◽  
The Mean ◽  
Self Motion ◽  
Head Rotations ◽  
Stimulation Of

Sixty vestibular nuclei neurons antidromically activated by electrical stimulation of the ventroposterior thalamus were recorded in two alert squirrel monkeys. The majority of these neurons were monosynaptically activated by vestibular nerve electrical stimulation. Forty-seven neurons responded to animal rotations around the earth-vertical axis; 16 of them also responded to translations in the horizontal plane. The mean sensitivity to 0.5-Hz rotations of 80°/s velocity was 0.40 ± 0.31 spikes·s−1·deg−1·s−1. Rotational responses were in phase with stimulus velocity. Sensitivities to 0.5-Hz translations of 0.1 g acceleration varied from 92.2 to 359 spikes·s−1· g−1 and response phases varied from 10.1° lead to −98° lag. The firing behavior in 28 neurons was studied during rotation of the whole animal, of the trunk, and voluntary and involuntary rotations of the head. Two classes of vestibulothalamic neurons were distinguished. One class of neurons generated signals related to movement of the head that were similar either when the head and trunk move together or when the head moves on the stationary trunk. A fraction of these neurons fired during involuntary head movements only. A second class of neurons generated signals related to movement of the trunk. They responded when the trunk moved alone or simultaneously with the head, but did not respond to head rotations while the trunk was stationary.

Self-motion perception during conflicting visual-vestibular acceleration

2009 ◽  
Vol 18 (5-6) ◽  
pp. 267-272
Author(s):  
Masayuki Ishida ◽  
Hiroaki Fushiki ◽  
Hiroshi Nishida ◽  
Yukio Watanabe
Keyword(s):  
Visual Information ◽  
Angular Acceleration ◽  
Vertical Axis ◽  
The Body ◽  
Whole Body ◽  
Large Field ◽  
Constant Acceleration ◽  
Conflicting Information ◽  
The Subject ◽  
Self Motion

Self-motion is known to be falsely perceived during exposure to the movement of visual surroundings. This illusory perception of visually-induced self-motion is known as "vection." The present study was conducted to examine the relative strengths of vection versus whole-body angular acceleration as they determine perceived self-rotation under conditions in which they individually provide conflicting information. Each subject was rotated for 90 s about a vertical axis at a constant acceleration, and a large-field visual surround in front of the subject was simultaneously rotated at a constant acceleration in the same direction, but at a magnitude of acceleration twice that of the body. This stimulus condition creates a sensory conflict between information from the vestibular/somatosensory systems and information from the visual system with respect to the direction of self-rotation. The subject eventually perceived self-acceleration in the direction of circular vection (CV), even though he or she was actually being accelerated in the direction opposite to CV. When the magnitude of contradictory chair acceleration exceeded the vestibular perceptual threshold, the onset latency of CV was significantly delayed. Our results suggest that visual information contributes to the perception of self-acceleration, and that illusory self-motion could overwhelm the feeling of self-acceleration due to inertial motion. CV would thus be a significant factor in determining spatial orientation in certain operational environments and flight conditions.

Drift Forces on a Floating Body of Simple Geometry Due to Second Order Interactions Between Pairs of Harmonics With Different Frequencies

2009 ◽  
Author(s):  
Joa˜o Pessoa ◽  
Nuno Fonseca ◽  
C. Guedes Soares
Keyword(s):  
Vertical Cylinder ◽  
Vertical Axis ◽  
Second Order ◽  
The Body ◽  
Floating Body ◽  
Order Problem ◽  
Simple Geometry ◽  
The Mean ◽  
Order Quantities ◽  
Drift Forces

The paper presents an investigation of the slowly varying second order drift forces on a floating body of simple geometry. The body is axis-symmetric about the vertical axis, like a vertical cylinder with a rounded bottom and a ratio of diameter to draft of 3.25. The hydrodynamic problem is solved with a second order boundary element method. The second order problem is due to interactions between pairs of incident harmonic waves with different frequencies, therefore the calculations are carried out for several difference frequencies with the mean frequency covering the whole frequency range of interest. Results include the surge drift force and pitch drift moment. The results are presented in several stages in order to assess the influence of different phenomena contributing to the global second order responses. Firstly the body is restrained and secondly it is free to move at the wave frequency. The second order results include the contribution associated with quadratic products of first order quantities, the total second order force, and the contribution associated to the free surface forcing.

Comparative Analysis of the Exposure and Surgical Freedom of the Endoscopic Extended Minipterional Craniotomy and the Transorbital Endoscopic Approach to the Anterior and Middle Cranial Fossae

2018 ◽  
Vol 17 (2) ◽  
pp. 174-181 ◽  
Author(s):  
Raywat Noiphithak ◽  
Juan C Yanez-Siller ◽  
Juan M Revuelta Barbero ◽  
Raymond I Cho ◽  
Bradley A Otto ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Standard Deviation ◽  
Minimally Invasive ◽  
Vertical Axis ◽  
Endoscopic Approach ◽  
Extended Version ◽  
Specific Approach ◽  
Significant Difference ◽  
Surgical Application ◽  
The Mean

AbstractBACKGROUNDNumerous minimally invasive approaches to the skull base have been successively developed. Knowledge of the surgical nuances of a specific approach may facilitate approach selection. This study sought to compare the nuances of an extended version of the minipterional craniotomy (EMPT) with those of the transorbital endoscopic approach (TOEA) to the anterior and middle cranial fossae (ACF and MCF, respectively).OBJECTIVETo quantitatively analyze and compare the area of exposure and surgical freedom between EMPT and TOEA to the ACF and MCF.METHODSEMPT and TOEA were carried out in 5 latex-injected cadaveric heads, bilaterally (10 sides). For each approach, the area of exposure, surgical freedom, and angle of attack were obtained with neuronavigation and statistically compared.RESULTSNo significant difference was found between the mean area of exposure of EMPT and TOEA at the ACF and MCF (P = .709 and .317, respectively). The mean exposure area at the ACF was of 13.4 ± 2.6 cm2 (mean ± standard deviation) and 13.0 ± 1.9 cm2 for EMPT and TOEA, respectively. Except for the crista galli, EMPT afforded a larger area of surgical freedom at all targets. EMPT also achieved significantly greater attack angles in vertical axis except to the crista galli. The horizontal attack angles to all targets were similar between approaches.CONCLUSIONEMPT and TOEA offer a comparable area of exposure at the ACF and MCF in the cadaver; however, the instrument maneuverability afforded by EMPT is superior. Further studies are necessary to better define their precise surgical application.

The Excretion of Isotope in Urea and Ammonia for Estimating Protein Turnover in Man with [15N]Glycine

1981 ◽  
Vol 61 (2) ◽  
pp. 217-228 ◽  
Author(s):  
E. B. Fern ◽  
P. J. Garlick ◽  
Margaret A. McNurlan ◽  
J. C. Waterlow
Keyword(s):  
Protein Metabolism ◽  
Protein Turnover ◽  
Mean Value ◽  
Intravenous Dose ◽  
Whole Body ◽  
Body Protein ◽  
End Products ◽  
The Mean ◽  
15N Urea ◽  
Normal Adults

1. Four normal adults were given [15N]-glycine in a single dose either orally or intravenously. Rates of whole-body protein turnover were estimated from the excretion of 15N in ammonia and in urea during the following 9 h. The rate derived from urea took account of the [15N]urea retained in body water. 2. In postabsorptive subjects the rates of protein synthesis given by ammonia were equal to those from urea, when the isotope was given orally, but lower when an intravenous dose was given. 3. In subjects receiving equal portions of food every 2 h rates of synthesis calculated from ammonia were much lower than those from urea whether an oral or intravenous isotope was given. Comparison of rates obtained during the post-absorptive and absorptive periods indicated regulation by food intake primarily of synthesis when measurements were made on urea, but regulation primarily of breakdown when measurements were made on ammonia. 4. These inconsistencies suggest that changes in protein metabolism might be assessed better by correlating results given by different end-products, and it is suggested that the mean value given by urea and ammonia will be useful for this purpose.

scholarly journals Differences in Demographic and Radiographic Characteristics between Patients with Visible and Invisible T1 Slopes on Lateral Cervical Radiographic Images

2022 ◽  
Vol 11 (2) ◽  
pp. 411
Author(s):  
Sadayuki Ito ◽  
Hiroaki Nakashima ◽  
Akiyuki Matsumoto ◽  
Kei Ando ◽  
Masaaki Machino ◽  
...  
Keyword(s):  
Pilot Study ◽  
Surgical Planning ◽  
Vertical Axis ◽  
Sagittal Vertical Axis ◽  
Radiographic Images ◽  
T1 Slope ◽  
Group I ◽  
Significant Difference ◽  
The Mean ◽  
Flexion And Extension

Introduction: The T1 slope is important for cervical surgical planning, and it may be invisible on radiographic images. The prevalence of T1 invisible cases and the differences in demographic and radiographic characteristics between patients whose T1 slopes are visible or invisible remains unexplored. Methods: This pilot study aimed to evaluate the differences in these characteristics between outpatients whose T1 slopes were visible or invisible on radiographic images. Patients (n = 60) who underwent cervical radiography, whose T1 slope was confirmed clearly, were divided into the visible (V) group and invisible (I) group. The following radiographic parameters were measured: (1) C2-7 sagittal vertical axis (SVA), (2) C2-7 angle in neutral, flexion, and extension positions. Results: Based on the T1 slope visibility, 46.7% of patients were included in group I. The I group had significantly larger C2-7 SVA than the V group for males (p < 0.05). The C2-7 SVA tended to be larger in the I group, without significant difference for females (p = 0.362). Discussion: The mean C2-7 angle in neutral and flexion positions was not significantly different between the V and I groups for either sex. The mean C2-7 angle in the extension position was greater in the V group. The T1 slope was invisible in males with high C2-7 SVA.

The directions of nystagmus and apparent self-motion evoked by caloric tests and angular accelerations

2002 ◽  
Vol 11 (6) ◽  
pp. 349-355
Author(s):  
Ognyan I. Kolev
Keyword(s):  
Motion Perception ◽  
Frontal Plane ◽  
Vertical Axis ◽  
The Body ◽  
The Self ◽  
Whole Body ◽  
Caloric Stimulation ◽  
Infrared Video ◽  
Axis Rotation ◽  
Self Motion

Purpose: To further investigate the direction of (I) nystagmus and (II) self-motion perception induced by two stimuli: (a) caloric vestibular stimulations and (b) a sudden halt during vertical axis rotation. Subjects and methods: Twelve normal humans received caloric stimulation at 44°C, 30°C, and 20°C while in a supine position with the head inclined 30° upwards. In a second test they were rotated around the vertical axis with the head randomly placed in two positions: tilted 30° forward or tilted 60° backward, at a constant velocity of 90°/sec for 2 minutes and then suddenly stopped. After both tests they were asked to describe their sensations of self-motion. Eye movements were recorded with an infrared video-technique. Results: Caloric stimulation evoked only horizontal nystagmus in all subjects and induced a non-uniform complex perception of angular in frontal and transverse planes (the former dominated) and linear movements along the antero-posterior axis (sinking dominated) of the subject's coordinates. The self-motion was felt with the whole body or with a part of the body. Generally the perception evoked by cold (30°C) and warm (44°C) calorics was similar, although there were some differences. The stronger stimulus (20°C) evoked not only quantitative but also qualitative differences in perception. The abrupt halt of rotation induced self-motion perception and nystagmus only in the plane of rotation. The self-motion was felt with the whole body. Conclusion: There was no difference in the nystagmus evoked by caloric stimulation and a sudden halt of vertical axis rotation (in head positions to stimulate the horizontal canals); however, the two stimuli evoked different perceptions of self-motion. Calorics provoked the sensation of self-rotation in the frontal plane and linear motion, which did not correspond to the direction of nystagmus, as well as arcing and a reset phenomenon during angular and linear self-motion, caloric-induced self-motion can be felt predominantly or only with a part of the body, depending on the self-motion intensity. The findings indicate that, unlike the self-motion induced by sudden halt of vertical axis rotation, several mechanisms take part in generating caloric-induced self-motion.

Sensorimotor aspects of high-speed artificial gravity: II. The effect of head position on illusory self motion

2003 ◽  
Vol 12 (5-6) ◽  
pp. 283-289
Author(s):  
Fred W. Mast ◽  
Nathaniel J. Newby ◽  
Laurence R. Young
Keyword(s):  
Healthy Subjects ◽  
Horizontal Plane ◽  
High Speed ◽  
Semicircular Canals ◽  
Vertical Axis ◽  
Head Position ◽  
Artificial Gravity ◽  
Axis Of Rotation ◽  
Self Motion

The effects of cross-coupled stimuli on the semicircular canals are shown to be influenced by the position of the subject's head with respect to gravity and the axis of rotation, but not by the subject's head position relative to the trunk. Seventeen healthy subjects made head yaw movements out of the horizontal plane while lying on a horizontal platform (MIT short radius centrifuge) rotating at 23 rpm about an earth-vertical axis. The subjects reported the magnitude and duration of the illusory pitch or roll sensations elicited by the cross-coupled rotational stimuli acting on the semicircular canals. The results suggest an influence of head position relative to gravity. The magnitude estimation is higher and the sensation decays more slowly when the head's final position is toward nose-up (gravity in the subject's head x-z-plane) compared to when the head is turned toward the side (gravity in the subject's head y-z-plane). The results are discussed with respect to artificial gravity in space and the possible role of pre-adaptation to cross-coupled angular accelerations on earth.

scholarly journals Intact transferrin receptors in human plasma and their relation to erythropoiesis

Blood ◽  
1990 ◽  
Vol 75 (1) ◽  
pp. 102-107 ◽  
Author(s):  
HA Huebers ◽  
Y Beguin ◽  
P Pootrakul ◽  
D Einspahr ◽  
CA Finch
Keyword(s):  
Human Plasma ◽  
Polyclonal Antibodies ◽  
Close Correlation ◽  
Enzyme Linked Immunosorbent Assay ◽  
Transferrin Receptors ◽  
Erythroid Hyperplasia ◽  
The Mean ◽  
Tissue Receptors ◽  
Mean Concentration ◽  
Normal Adults

Abstract Intact transferrin receptor molecules complexed with transferrin were found in human plasma. The concentration of receptors was determined by an enzyme-linked immunosorbent assay that uses polyclonal antibodies. The mean concentration of 8,279 micrograms/L in 56 normal adults appears to be unrelated to age or sex. Additional receptor measurements were performed on plasmas from 260 subjects with erythropoietic disorders. Decreased concentration of plasma receptors was found in patients with erythroid hypoplasia and increased numbers in those with erythroid hyperplasia. Ferrokinetic measurements of erythropoiesis were compared with numbers of receptors in 148 subjects, and a close correlation was found (r = .86). Both sets of values, measured in different conditions and expressed in relation to normal, were consistent with expected values. Receptor values were unproportionally increased only in conditions of iron deficiency. It is concluded that plasma receptors have a constant relationship to tissue receptors, and their number in most instances reflects the rate of erythropoiesis.

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