Effects of resistance exercise on antioxidant enzyme activities and apoptosis-related protein expression of hippocampus in OLETF rats

2018 ◽  
Vol 26 (3) ◽  
pp. 457-467 ◽  
Author(s):  
Min-Ki Lee ◽  
Chun-Seop Jung ◽  
Jin-Hwan Yoon ◽  
Namju Lee
Keyword(s):  
Protein Expression ◽  
Resistance Exercise ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Antioxidant Enzyme Activities ◽  
Related Protein ◽  
Oletf Rats ◽  
Apoptosis Related Protein

Effect of dietary curcumin and capsaicin on testicular and hepatic oxidant–antioxidant status in rats fed a high-fat diet

2019 ◽  
Vol 44 (7) ◽  
pp. 774-782 ◽  
Author(s):  
Sevda Tanrıkulu-Küçük ◽  
Canan Başaran-Küçükgergin ◽  
Muhammed Seyithanoğlu ◽  
Semra Doğru-Abbasoğlu ◽  
Hikmet Koçak ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protein Expression ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
High Fat Diet ◽  
Antioxidant Status ◽  
Control Group ◽  
Antioxidant Enzyme Activities ◽  
Transferase Activity ◽  
High Fat

This study investigated the effects of curcumin and capsaicin on testicular and hepatic oxidant–antioxidant status in rats fed a high-fat diet (HFD). Male Sprague–Dawley rats were divided into 5 groups (8 rats per group). The control group was fed a normal control diet (standard laboratory chow), the HFD group was fed HFD (60% of total calories from fat), the HFD+CUR group received HFD supplemented with curcumin (1.5 g curcumin/kg HFD), the HFD+CAP group was given HFD supplemented with capsaicin (0.15 g capsaicin/kg HFD), and the HFD+CUR+CAP group received HFD supplemented with curcumin and capsaicin for 16 weeks. Hepatic and testicular thiobarbituric acid reactive substances (TBARS), reactive oxygen species (ROS), glutathione (GSH) levels, glutathione transferase activity, and Cu-Zn superoxide dismutase, glutathione peroxidase, and catalase protein expression and enzyme activities were measured. Protein expression was determined by Western blotting. GSH levels and antioxidant enzyme activities were measured with colorimetric methods. HFD slightly increased hepatic and testicular oxidative stress parameters. GSH levels did not change between groups. TBARS and ROS levels were significantly reduced in the HFD+CUR+CAP group compared with the HFD group. Liver and testis antioxidant enzyme activities and expression increased significantly with combined capsaicin and curcumin treatment. Curcumin and capsaicin treatment attenuated testicular and hepatic oxidative stress and enhanced the antioxidant defense system. The combination of capsaicin and curcumin with HFD seems to have some remarkable and beneficial effects on testicular oxidative damage in the fatty liver rat model.

Brain antioxidant responses to acute iron and copper intoxications in rats

Metallomics ◽  
2014 ◽  
Vol 6 (11) ◽  
pp. 2083-2089 ◽  
Author(s):  
Jimena Semprine ◽  
Nidia Ferrarotti ◽  
Rosario Musacco-Sebio ◽  
Christian Saporito-Magriñá ◽  
Julián Fuda ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protein Expression ◽  
Antioxidant Enzyme ◽  
Antioxidant System ◽  
Enzyme Activities ◽  
Antioxidant Enzyme Activities ◽  
Antioxidant Responses

The response of brain antioxidant system to the oxidative stress following Fe and Cu overloads involves: antioxidant consumption and an adaptive increase in antioxidant enzyme activities and protein expression.

scholarly journals Keratocyte apoptosis and corneal antioxidant enzyme activities after refractive corneal surgery

Eye ◽  
2002 ◽  
Vol 16 (1) ◽  
pp. 63-68 ◽  
Author(s):  
K Bilgihan ◽  
A Bilgihan ◽  
U Adiguzel ◽  
C Sezer ◽  
O Yis ◽  
...  
Keyword(s):  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Antioxidant Enzyme Activities ◽  
Corneal Surgery
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