scholarly journals Using non-nutritive sucking to support feeding development for premature infants: A commentary on approaches and current practice

2018 ◽  
Vol 11 (3) ◽  
pp. 147-152 ◽  
Author(s):  
C. Harding ◽  
H. Cockerill ◽  
C. Cane ◽  
J. Law
2006 ◽  
Vol 25 (3) ◽  
pp. 223-224 ◽  
Author(s):  
Elizabeth Pulsifer-Anderson ◽  
Ronnie Guillet

ARETROSPECTIVE ANALYSIS OF data from 11,000 preterm infants in neonatal intensive care units (NICUs) in the U.S. found that infants receiving H2 blockers such as Zantac, Tagamet, Pepcid, and Axid were more likely to develop necrotizing enterocolitis (NEC).1 The study was funded by the National Institutes of Health (NIH). As a result of the findings of this study, Elias A. Zerhouni, MD, Director of the National Institutes of Health, issued a press release in February, 2006, stating, “This study strongly suggests that the current practice of prescribing H2 blockers to prevent or treat acid reflux in premature infants needs to be carefully reevaluated by all concerned in light of these new findings.”2


Neonatology ◽  
1969 ◽  
Vol 14 (5-6) ◽  
pp. 270-278 ◽  
Author(s):  
J.M. Dubignon ◽  
D. Campbell ◽  
M.W. Partington

2020 ◽  
Vol 29 (2S) ◽  
pp. 1022-1029
Author(s):  
Ruby Bartolome ◽  
Tomoko Kaneko-Tarui ◽  
Jill Maron ◽  
Emily Zimmerman

Purpose Successful oral feeding and speech emergence are dependent upon the coordination of shared oral muscles and facial nerves. We aimed to determine if the speech-associated genes, forkhead box P2 (FOXP2) , contactin-associated protein-like 2 (CNTNAP2 ), glutamate receptor, ionotropic, N-methyl D-aspartate 2A (GRIN2A) , and neurexin 1, were detectable in neonatal saliva and could predict feeding outcomes in premature newborns. Method In this prospective, observational, preliminary study, saliva collected from 51 premature infants (gestational ages: 30–34 6/7 weeks) at different stages of oral feeding development underwent gene expression analysis. Binary (+/–) expression profiles were explored and examined in relation to days to achieve full oral feeds. Results GRIN2A and neurexin 1 rarely amplified in neonatal saliva and were not informative. Infants who amplified FOXP2 but not CNTNAP2 at the start of oral feeds achieved oral feeding success 3.20 (95% CI [−2.5, 8.9]) days sooner than other gene combinations. Conclusions FOXP2 and CNTNAP2 may be informative in predicting oral feeding outcomes in newborns. Salivary analysis at the start of oral feeding trials may inform feeding outcomes in this population and warrants further investigation.


2021 ◽  
Vol 14 (3) ◽  
pp. 379-387
Author(s):  
Alireza Alidad ◽  
Maryam Tarameshlu ◽  
Leila Ghelichi ◽  
Hamid Haghani

PURPOSE: Feeding problems are common in premature infants (PIs) and may lead to negative consequences such as malnutrition, dehydration, excessive weight loss, as well as developmental and psychological deficits. Moreover, they are associated with increased length of hospital stay/cost. There is not enough evidence on how feeding problems should be treated in PIs. The goal of this study was to investigate the effects of non-nutritive sucking combined with oral motor stimulation and oral support on feeding performance in PIs. METHODS: A single-blind randomized clinical trial was performed on 44 PIs with feeding problems. Patients were randomly categorized into two groups: (1) combined intervention (CI) and (2) non-nutritive sucking (NNS). The CI group received NNS, oral motor stimulation and oral support simultaneously. Infants in both groups received 14 treatment sessions for 14 consecutive days. The Preterm Oral Feeding Readiness Assessment Scale (POFRAS) was used as the primary outcome measure. Weight, volume of milk intake, time to achieve full oral feeding, and length of hospital stay were secondary outcome measures. All measures were assessed before treatment, after the 7th session, after the 14th session, and after 7 days after the end of treatment. RESULTS: Both groups improved in all outcome measures across time (P < 0.001). The improvements in the POFRAS, volume of milk intake, and time to achieve full oral feeding were significantly greater in the CI group than the NNS group (P < 0.001). The improvements attained in weight and length of hospital stay were not significantly different between the CI and NNS groups (P > 0.05). Large effect sizes were found for POFRAS score in both CI (d = 3.98) and NNS (d = 2.19) groups. CONCLUSION: The current study showed that the combined intervention including NNS, oral motor stimulation, and oral support significantly improved the feeding performance in PIs.


2020 ◽  
Vol 20 (2) ◽  
pp. 1028-1034
Author(s):  
Zobair Ebrahimi ◽  
Hadi Moradi ◽  
Shahin Jafarabadi Ashtiani

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