Diffusion tensor imaging findings in neurologically asymptomatic patients with end stage renal disease

2011 ◽  
Vol 29 (1) ◽  
pp. 111-116 ◽  
Author(s):  
Han Sun Kim ◽  
Jong Won Park ◽  
Dai Seg Bai ◽  
Jin Young Jeong ◽  
Ji Heon Hong ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Diffusion Tensor ◽  
Imaging Findings ◽  
Asymptomatic Patients ◽  
Stage Renal Disease ◽  
End Stage

End-Stage Renal Disease: In Vivo Diffusion-Tensor Imaging of Silent White Matter Damage

Radiology ◽  
2009 ◽  
Vol 252 (2) ◽  
pp. 518-525 ◽  
Author(s):  
Tsyh-Jyi Hsieh ◽  
Jer-Ming Chang ◽  
Hung-Yi Chuang ◽  
Chih-Hung Ko ◽  
Miao-Ling Hsieh ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Diffusion Tensor ◽  
White Matter Damage ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Prognostic Value of Troponin T and I Among Asymptomatic Patients With End-Stage Renal Disease

Circulation ◽  
2005 ◽  
Vol 112 (20) ◽  
pp. 3088-3096 ◽  
Author(s):  
Nadia A. Khan ◽  
Brenda R. Hemmelgarn ◽  
Marcello Tonelli ◽  
Christopher R. Thompson ◽  
Adeera Levin
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Prognostic Value ◽  
Troponin T ◽  
Asymptomatic Patients ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Investigating the utility of COVID-19 antibody testing in end-stage renal disease patients receiving haemodialysis: a cohort study in the United Kingdom

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Olivia Wickens ◽  
Rajkumar Chinnadurai ◽  
Fahmida Mannan ◽  
Frida Svendsen ◽  
Mirza Yasar Baig ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Humoral Response ◽  
Infection Prevention And Control ◽  
Serological Testing ◽  
Antibody Testing ◽  
Asymptomatic Patients ◽  
Chi Squared ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background End-stage renal disease (ESRD) patients receiving haemodialysis (HD) are a vulnerable group of patients with increased mortality from COVID-19. Despite improved understanding, the duration of host immunity following COVID-19 infection and role of serological testing alone or in addition to real-time reverse transcription polymerase chain reaction (rRT-PCR) testing in the HD population is not fully understood, which this study aimed to investigate. Methods There were two parts to this study. Between 15th March 2020 to 15th July 2020, patients receiving HD who tested positive on rRT-PCR for SARS-CoV-2 were recruited into the COVID-19 arm, whilst asymptomatic patients without a previous diagnosis of COVID-19 were recruited to the epidemiological arm of the Salford Kidney Study (SKS). All patients underwent monthly testing for anti-SARS-CoV-2 antibodies as per routine clinical practice since August 2020. The aims were twofold: firstly, to determine seroprevalence and COVID-19 exposure in the epidemiological arm; secondly, to assess duration of the antibody response in the COVID-19 arm. Baseline characteristics were reviewed between groups. Statistical analysis was performed using SPSS. Mann-Whitney U and Chi-squared tests were used for testing significance of difference between groups. Results In our total HD population of 411 patients, 32 were PCR-positive for COVID-19. Of the remaining patients, 237 were recruited into the SKS study, of whom 12 (5.1%) had detectable anti-SARS-CoV-2 antibodies. Of the 32 PCR-positive patients, 27 (84.4%) were symptomatic and 25 patients admitted to hospital due to their symptoms. Of the 22 patients in COVID-19 arm that underwent testing for anti-SARS-CoV-2 IgG antibodies beyond 7 months, all had detectable antibodies. A higher proportion of the patients with COVID-19 were frail compared to patients without a diagnosis of COVID-19 (64.3% vs 34.1%, p = 0.003). Other characteristics were similar between the groups. Over a median follow up of 7 months, a higher number of deaths were recorded in patients with a diagnosis of COVID-19 compared to those without (18.7% vs 5.9%, p = 0.003). Conclusions Serological testing in the HD population is a valuable tool to determine seroprevalence, monitor exposure, and guide improvements for infection prevention and control (IPC) measures to help prevent local outbreaks. This study revealed HD patients mount a humoral response detectable until at least 7 months after COVID-19 infection and provides hope of similar protection with the vaccines recently approved.

scholarly journals Aberrant Functional Connectome in Neurologically Asymptomatic Patients with End-Stage Renal Disease

PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0121085 ◽  
Author(s):  
Xiaofen Ma ◽  
Guihua Jiang ◽  
Shumei Li ◽  
Jinhui Wang ◽  
Wenfeng Zhan ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Functional Connectome ◽  
Asymptomatic Patients ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Abnormal Interhemispheric Functional Connectivity in Neurologically Asymptomatic Patients With End-Stage Renal Disease

2021 ◽  
Author(s):  
Yan Xue ◽  
Zhuanzhuan Wu ◽  
Shuyan Li ◽  
Bo Li ◽  
Gang Sun ◽  
...  
Keyword(s):  
Functional Connectivity ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Brain Regions ◽  
Maintenance Hemodialysis ◽  
Precentral Gyrus ◽  
Asymptomatic Patients ◽  
Potential Biomarker ◽  
Stage Renal Disease ◽  
End Stage

Abstract Objective: This study aims to investigate the alterations in interhemispheric functional connectivity in neurologically asymptomatic patients with end-stage renal disease (ESRD) undergoing maintenance hemodialysis (HD) using resting-state functional magnetic resonance imaging (rs-fMRI) with voxel-mirrored homotopic connectivity (VMHC) algorithm. Methods: The rs-fMRI data were acquired from 40 neurologically asymptomatic patients with ESRD and 34 matched healthy control (HC) subjects. All subjects underwent neuropsychological tests, and patients with ESRD underwent laboratory tests. Intergroup VMHC differences in the voxel manner were analyzed. Correlation analysis was performed to evaluate the relationships between VMHC values and clinical variables in patients with ESRD. We further performed a receptive operation characteristic (ROC) analysis to confirm the sensitivity and specificity of our results.Results: Compared with HCs, patients with ESRD exhibited significantly decreased VMHC values in the inferior parietal lobule (IPL), superior temporal gyrus (STG), insula, precentral gyrus (PreCG), middle occipital gyrus (MOG), and calcarine/lingual/cuneus. Patients with ESRD did not exhibit increased VMHC values in any brain regions compared with HCs. Furthermore, the VMHC value of MOG was positively correlated with hemoglobin levels in patients with ESRD.Conclusions: The results revealed that the impairment of interhemispheric coordination in patients with ESRD, which provided preliminary evidence of VMHC as a potential biomarker of patients with ESRD.

scholarly journals Prevalence of Peripheral Arterial Disease among End Stage Renal Disease Patients

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
R R W Morkos ◽  
A M Shahan ◽  
A S Elserafy ◽  
H F Hanna
Keyword(s):  
Peripheral Arterial Disease ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Arterial Disease ◽  
Control Group ◽  
Asymptomatic Patients ◽  
Peripheral Arterial ◽  
Stage Renal Disease ◽  
End Stage ◽  
Regular Hemodialysis

Abstract Background Patients with End Stage Renal Disease are more susceptible to develop Peripheral Arterial Disease. So, screening is helpful for early diagnosis. Objectives The aim of this study is to screen and calculate the prevalence of asymptomatic patients on regular hemodialysis for presence of PAD. Methods The study included 100 asymptomatic patients on regular hemodialysis and below 60 years old to be screened for presence of PAD. All selected patients have been subjected to ABI assessment using the Doppler. It was found that the prevalence of PAD among ESRD patients is 26% of which 80.8% had bilateral PAD and 19.2% had unilateral disease. The results showed that females had statistically significant higher risk of developing PAD than males. The study showed also that A1C level in patients who have no diabetes carries statistically significant results. The mean A1C level for the study group was 5.56 ± 0.70 and the control group was 4.92 ± 0.73. The p value was 0.000. The A1C level cut off value was > 5.3. Conclusion Renal impairment is an important risk factor for developing PAD in absence of traditional risk factors such as DM, hypertension, or dyslipidemia. Prevalence of PAD was 26% in our study. ABI is a simple non-invasive modality of screening for PAD. Females are at higher risk to develop PAD than males by ∼ 2.7 fold. Although diabetes is absent, A1C level > 5.3 is significantly correlating with the risk of PAD.

Sign in / Sign up

Export Citation Format

Share Document