Motor outcome prediction using diffusion tensor tractography of the corticospinal tract in large middle cerebral artery territory infarct

2013 ◽  
Vol 32 (3) ◽  
pp. 583-590 ◽  
Author(s):  
Eun Hyuk Kim ◽  
Jun Lee ◽  
Sung Ho Jang
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Outcome Prediction ◽  
Corticospinal Tract ◽  
Diffusion Tensor ◽  
Diffusion Tensor Tractography ◽  
Middle Cerebral Artery Territory ◽  
Motor Outcome

Motor outcome prediction using diffusion tensor tractography in pontine infarct

2008 ◽  
Vol 64 (4) ◽  
pp. 460-465 ◽  
Author(s):  
Sung Ho Jang ◽  
Daiseg Bai ◽  
Su Min Son ◽  
Jun Lee ◽  
Dae-Shik Kim ◽  
...  
Keyword(s):  
Outcome Prediction ◽  
Diffusion Tensor ◽  
Diffusion Tensor Tractography ◽  
Motor Outcome ◽  
Pontine Infarct

scholarly journals The anesthetic approach for endovascular recanalization therapy depends on the lesion site in acute ischemic stroke

2021 ◽  
Author(s):  
Kilian Fröhlich ◽  
Gabriela Siedler ◽  
Svenja Stoll ◽  
Kosmas Macha ◽  
Thomas M. Kinfe ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Middle Cerebral Artery ◽  
Acute Ischemic Stroke ◽  
Cerebral Artery ◽  
Posterior Circulation ◽  
Neurological Deficits ◽  
Stroke Severity ◽  
Lesion Volume ◽  
Middle Cerebral Artery Territory ◽  
Cerebral Lesion

Abstract Purpose Endovascular therapy (EVT) of large-vessel occlusion in acute ischemic stroke (AIS) may be performed in general anesthesia (GA) or conscious sedation (CS). We intended to determine the contribution of ischemic cerebral lesion sites on the physician’s decision between GA and CS using voxel-based lesion symptom mapping (VLSM). Methods In a prospective local database, we sought patients with documented AIS and EVT. Age, stroke severity, lesion volume, vigilance, and aphasia scores were compared between EVT patients with GA and CS. The ischemic lesions were analyzed on CT or MRI scans and transformed into stereotaxic space. We determined the lesion overlap and assessed whether GA or CS is associated with specific cerebral lesion sites using the voxel-wise Liebermeister test. Results One hundred seventy-nine patients with AIS and EVT were included in the analysis. The VLSM analysis yielded associations between GA and ischemic lesions in the left hemispheric middle cerebral artery territory and posterior circulation areas. Stroke severity and lesion volume were significantly higher in the GA group. The prevalence of aphasia and aphasia severity was significantly higher and parameters of vigilance lower in the GA group. Conclusions The VLSM analysis showed associations between GA and ischemic lesions in the left hemispheric middle cerebral artery territory and posterior circulation areas including the thalamus that are known to cause neurologic deficits, such as aphasia or compromised vigilance, in AIS-patients with EVT. Our data suggest that higher disability, clinical impairment due to neurological deficits like aphasia, or reduced alertness of affected patients may influence the physician’s decision on using GA in EVT.

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