Factors associated with long-term mechanical ventilation in extremely preterm infants

2018 ◽  
Vol 11 (1) ◽  
pp. 29-35 ◽  
Author(s):  
Lina Yossef ◽  
Edward G. Shepherd ◽  
Susan Lynch ◽  
Kristina M. Reber ◽  
Leif D. Nelin
Keyword(s):  
Mechanical Ventilation ◽  
Preterm Infants ◽  
Factors Associated ◽  
Extremely Preterm ◽  
Extremely Preterm Infants

scholarly journals Short- and Long-Term Outcomes of Extremely Preterm Infants in Japan According to Outborn/Inborn Birth Status*

2019 ◽  
Vol 20 (10) ◽  
pp. 963-969 ◽  
Author(s):  
Yoshihito Sasaki ◽  
Kaoru Ishikawa ◽  
Akira Yokoi ◽  
Tomoaki Ikeda ◽  
Kazuo Sengoku ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Long Term Outcomes ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Short And Long Term

scholarly journals Bronchopulmonary Dysplasia: Can We Agree on a Definition?

2018 ◽  
Vol 35 (06) ◽  
pp. 537-540 ◽  
Author(s):  
Deepak Jain ◽  
Eduardo Bancalari
Keyword(s):  
Respiratory Failure ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Nasal Cannula ◽  
Clinical Practices ◽  
Unique Challenge ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Respiratory Outcomes

AbstractThe advances in obstetric and neonatal care over the last half century have resulted in changes in pathophysiology and clinical presentation of bronchopulmonary dysplasia (BPD). In contrast to the original description of BPD by Northway et al as a severe lung injury in relatively mature preterm infants, the most common form of BPD currently is characterized by chronic respiratory insufficiency in extremely preterm infants. This evolution in the presentation of BPD, along with changes in respiratory support strategies such as increased use of nasal cannula oxygen, has presented a unique challenge to find a definition that describes the severity of lung damage and predict the long-term respiratory outcomes with some accuracy.The limitations of current definitions of BPD include inconsistent correlation with long-term respiratory outcomes, inability to classify infants dying from severe respiratory failure prior to 36 weeks' postmenstrual age, and potential inappropriate categorization of infants on nasal cannula oxygen or with extrapulmonary causes of respiratory failure. In the long term, the aim for a new definition of BPD is to develop a classification based on the pathophysiology and objective lung function evaluation providing a more accurate assessment for individual patients. Until then, a consensus definition that encompasses current clinical practices, provides reasonable prediction of later respiratory outcomes, and is relatively simple to use should be achieved.

Early inhaled budesonide in extremely preterm infants decreases long‐term respiratory morbidity

2020 ◽  
Vol 55 (5) ◽  
pp. 1124-1130 ◽  
Author(s):  
Jana Tukova ◽  
Jan Smisek ◽  
Blanka Zlatohlavkova ◽  
Richard Plavka ◽  
Daniela Markova
Keyword(s):  
Preterm Infants ◽  
Respiratory Morbidity ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Inhaled Budesonide

scholarly journals Factors Associated With Feeding Progression in Extremely Preterm Infants

2015 ◽  
Vol 64 (3) ◽  
pp. 159-167 ◽  
Author(s):  
Jinhee Park ◽  
George Knafl ◽  
Suzanne Thoyre ◽  
Debra Brandon
Keyword(s):  
Preterm Infants ◽  
Factors Associated ◽  
Extremely Preterm ◽  
Extremely Preterm Infants

scholarly journals Systemic inflammation associated with mechanical ventilation among extremely preterm infants

Cytokine ◽  
2013 ◽  
Vol 61 (1) ◽  
pp. 315-322 ◽  
Author(s):  
Carl L. Bose ◽  
Matthew M. Laughon ◽  
Elizabeth N. Allred ◽  
T. Michael O’Shea ◽  
Linda J. Van Marter ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Preterm Infants ◽  
Systemic Inflammation ◽  
Extremely Preterm ◽  
Extremely Preterm Infants

Tracheomegaly among Extremely Preterm Infants on Prolonged Mechanical Ventilation

2020 ◽  
Vol 218 ◽  
pp. 231-233.e1
Author(s):  
Hussnain Mirza ◽  
Laura Varich ◽  
William F. Sensakovic ◽  
Kharina Guruvadoo ◽  
Ivey Royall ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Preterm Infants ◽  
Prolonged Mechanical Ventilation ◽  
Extremely Preterm ◽  
Extremely Preterm Infants

Prolonged Mechanical Ventilation: Challenges to Nurses and Outcome in Extremely Preterm Babies

2015 ◽  
Vol 35 (4) ◽  
pp. 58-66 ◽  
Author(s):  
Rachel A. Joseph
Keyword(s):  
Mechanical Ventilation ◽  
Prolonged Mechanical Ventilation ◽  
Invasive Mechanical Ventilation ◽  
Technological Advances ◽  
Improved Outcomes ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Careful Handling ◽  
Preterm Babies

Worldwide, about 15 million infants are born prematurely each year. Technological advances, including invasive mechanical ventilation, play a major role in the survival of extremely preterm babies. Those who survive may have prolonged morbid conditions that result in long-term sequelae. Nurses face several challenges during the hospitalization of these infants. Vigilant care, monitoring, and careful handling of the infants can prevent infections and long-term complications. Newer, less invasive technologies are promising for improved outcomes in extremely preterm infants.

scholarly journals Indications for and Risks of Noninvasive Respiratory Support

Neonatology ◽  
2021 ◽  
pp. 1-9
Author(s):  
Kirsten Glaser ◽  
Clyde J. Wright
Keyword(s):  
Mechanical Ventilation ◽  
Lung Injury ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Invasive Mechanical Ventilation ◽  
Respiratory Support ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Neonatal Lung ◽  
The Individual

Within the last decades, therapeutic advances have significantly improved the survival of extremely preterm infants. In contrast, the incidence of major neonatal morbidities, including bronchopulmonary dysplasia, has not declined. Given the well-established relationship between exposure to invasive mechanical ventilation and neonatal lung injury, neonatologists have sought for effective strategies of noninvasive respiratory support in high-risk infants. Continuous positive airway pressure has replaced invasive mechanical ventilation for the initial stabilization and the treatment of respiratory distress syndrome. Today, noninvasive respiratory support has been adopted even in the tiniest babies with the highest risk of lung injury. Moreover, different modes of noninvasive respiratory support supplemented by a number of adjunctive measures and rescue strategies have entered clinical practice with the goal of preventing intubation or reintubation. However, does this unquestionably important paradigm shift to strategies focused on noninvasive support lull us into a false sense of security? Can we do better in (i) identifying those very immature preterm infants best equipped for noninvasive stabilization, can we improve (ii) determinants of failure of noninvasive respiratory support in the individual infant and underlying etiology, and can we enhance (iii) success of noninvasive respiratory support and (iv) better prevent ultimate harm to the developing lung? With increased survival of infants at the highest risk of developing lung injury and an unchanging burden of bronchopulmonary dysplasia, we should question indiscriminate use of noninvasive respiratory support and address the above issues.

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