Effects of Nigerian black finger millet (Eleusine coracana L. Gaertn.) seed coat supplementation on streptozotocin-induced diabetic rats

2015 ◽  
Vol 8 (2) ◽  
pp. 93-100 ◽  
Author(s):  
Onyike Elewechi ◽  
Okoyomoh Kingsley ◽  
Ndidi Uche Samuel ◽  
Olowoniyi Olufunsho Dayo ◽  
Adejo Godwin Ojochogu ◽  
...  
Keyword(s):  
Seed Coat ◽  
Finger Millet ◽  
Diabetic Rats ◽  
Eleusine Coracana

scholarly journals Amelioration of hyperglycaemia and its associated complications by finger millet (Eleusine coracanaL.) seed coat matter in streptozotocin-induced diabetic rats

2010 ◽  
Vol 104 (12) ◽  
pp. 1787-1795 ◽  
Author(s):  
Shanmugam Shobana ◽  
Mysore R. Harsha ◽  
Kalpana Platel ◽  
Krishnapura Srinivasan ◽  
Nagappa G. Malleshi
Keyword(s):  
Seed Coat ◽  
Finger Millet ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Tubular Structures ◽  
Glycation End Products ◽  
Body Weights ◽  
Millet Seed ◽  
Effect Of Feeding ◽  
Partial Reversal

Finger millet (Eleusine coracana) is extensively cultivated and consumed in India and Africa. The millet seed coat is a rich source of dietary fibre and phenolic compounds. The effect of feeding a diet containing 20 % finger millet seed coat matter (SCM) was examined in streptozotocin-induced diabetic rats. Diabetic rats maintained on the millet SCM diet (diabetic experimental (DE) group) for 6 weeks exhibited a lesser degree of fasting hyperglycaemia and partial reversal of abnormalities in serum albumin, urea and creatinine compared with the diabetic control (DC) group. The DE group of rats excreted comparatively lesser amounts of glucose, protein, urea and creatinine and was accompanied by improved body weights compared with their corresponding controls. Hypercholesterolaemia and hypertriacylglycerolaemia associated with diabetes were also notably reversed in the DE group. Slit lamp examination of the eye lens revealed an immature subcapsular cataract with mild lenticular opacity in the DE group of rats compared to the mature cataract with significant lenticular opacity and corneal vascularisation in the DC group. Lower activity of lens aldose reductase, serum advanced glycation end products and blood glycosylated Hb levels were observed in the DE group. The millet SCM feeding showed pronounced ameliorating effects on kidney pathology as reflected by near normal glomerular and tubular structures and lower glomerular filtration rate compared with the shrunken glomerulus, tubular vacuolations in the DC group. Thus, the present animal study evidenced the hypoglycaemic, hypocholesterolaemic, nephroprotective and anti-cataractogenic properties of finger millet SCM, suggesting its utility as a functional ingredient in diets for diabetics.

Dephytinization of seed coat matter of finger millet (Eleusine coracana) by Lactobacillus pentosus CFR3 to improve zinc bioavailability

LWT ◽  
2018 ◽  
Vol 87 ◽  
pp. 562-566 ◽  
Author(s):  
Girish K. Amritha ◽  
Usha Dharmaraj ◽  
Prakash M. Halami ◽  
G. Venkateswaran
Keyword(s):  
Seed Coat ◽  
Finger Millet ◽  
Eleusine Coracana ◽  
Lactobacillus Pentosus ◽  
Zinc Bioavailability

Improved oxidative stability of peanut oil through addition of finger millet ( Eleusine coracana ) seed coat polyphenols

2019 ◽  
Vol 43 (3) ◽  
Author(s):  
Velur Geetha Balasubramaniam ◽  
Saravanapandian Sathvika ◽  
Palaniappan Ayyappan ◽  
Usha Antony
Keyword(s):  
Oxidative Stability ◽  
Seed Coat ◽  
Finger Millet ◽  
Eleusine Coracana ◽  
Peanut Oil

scholarly journals Antidiabetic and Hypolipidaemic Action of Finger Millet (Eleusine coracana)-Enriched Probiotic Fermented Milk

2020 ◽  
Vol 58 (2) ◽  
pp. 192-202
Author(s):  
Jinal Kesharbhai Chaudhary ◽  
Sreeja Mudgal
Keyword(s):  
Body Mass ◽  
Finger Millet ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Fermented Milk ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Eleusine Coracana ◽  
Lactobacillus Helveticus ◽  
Enriched Milk

Research background. Diabetes is a chronic multi-system disease having long term consequences to the health of people suffering from it. This study investigates the role of finger millet (Eleusine coracana)-enriched probiotic fermented milk in alleviating the diabetic complications in streptozotocin-induced diabetic rats. Experimental approach. The probiotic strain used in the study was Lactobacillus helveticus MTCC 5463. Study comprised six groups each containing 6 Sprague Dawley rats: two controls (nondiabetic and diabetic), and four diabetic groups fed finger millet-enriched probiotic fermented milk, probiotic fermented milk, finger millet flour or metformin (standard drug). Samples were administered orally for four weeks, and parameters associated with diabetic disorders were studied. Results and conclusions. Oral administration of finger millet-enriched milk significantly (p<0.001) decreased (64.26 %) the fasting blood glucose level of diabetic rats compared to metformin (56.43 %) and diabetic groups receiving the probiotic fermented milk (18.88 %) and finger millet flour (47.14 %) after four weeks of treatment. The finger millet-enriched milk significantly ameliorated the diabetic symptoms polyphagia and polydipsia and improved body mass. In diabetic control group, body mass was reduced up to 15.60 % at the end of experiment, while in the group receiving the probiotic fermented milk, body mass significantly (p<0.0001) increased by about 5-30 %. Significant (p<0.0001) reduction in total cholesterol, triglyceride levels in the groups treated with finger millet flour, finger millet-enriched probiotic fermented milk and probiotic fermented milk was observed compared to diabetic control rats. The probiotic fermented milk enriched with finger millet caused significant (p<0.05) decrease in low-density lipoprotein and very-low-density lipoprotein levels (p<0.0001) and insignificant increase in high-density lipoprotein level. A reversal of altered activities of hepatic marker enzymes aspartate transaminase and alanine transaminase was observed in the group receiving the probiotic milk enriched with finger millet. Histological observations of pancreatic tissues and liver showed that the enriched milk prevents more severe changes in the acinar cells and ameliorated the inflammation and alteration in the liver structure to some extent. Therefore, the finger millet-enriched probiotic fermented milk can be a potential functional food in the management of diabetes. Novelty and scientific contribution. This is the only paper reporting about the antidiabetic potential of finger millet-enriched milk fermented using probiotic Lactobacillus helveticus MTCC 5463 and Streptococcus thermophilus MTCC 5460. It also shows the synergistic antidiabetic effect of milk and finger millet used in combination, thus offering a novel functional food.

Assessment of genome origins and genetic diversity in the genus Eleusine with DNA markers

Genome ◽  
1995 ◽  
Vol 38 (4) ◽  
pp. 757-763 ◽  
Author(s):  
Shanmukhaswami S. Salimath ◽  
Antonio C. de Oliveira ◽  
Jeffrey L. Bennetzen ◽  
Ian D. Godwin
Keyword(s):  
Restriction Fragment Length Polymorphism ◽  
Length Polymorphism ◽  
Fragment Length ◽  
Finger Millet ◽  
Dna Marker ◽  
Fragment Length Polymorphism ◽  
Eleusine Coracana ◽  
Randomly Amplified Polymorphic Dna ◽  
Simple Sequence ◽  
Restriction Fragment Length

Finger millet (Eleusine coracana), an allotetraploid cereal, is widely cultivated in the arid and semiarid regions of the world. Three DNA marker techniques, restriction fragment length polymorphism (RFLP), randomly amplified polymorphic DNA (RAPD), and inter simple sequence repeat amplification (ISSR), were employed to analyze 22 accessions belonging to 5 species of Eleusine. An 8 probe – 3 enzyme RFLP combination, 18 RAPD primers, and 6 ISSR primers, respectively, revealed 14, 10, and 26% polymorphism in 17 accessions of E. coracana from Africa and Asia. These results indicated a very low level of DNA sequence variability in the finger millets but did allow each line to be distinguished. The different Eleusine species could be easily identified by DNA marker technology and the 16% intraspecific polymorphism exhibited by the two analyzed accessions of E. floccifolia suggested a much higher level of diversity in this species than in E. coracana. Between species, E. coracana and E. indica shared the most markers, while E. indica and E. tristachya shared a considerable number of markers, indicating that these three species form a close genetic assemblage within the Eleusine. Eleusine floccifolia and E. compressa were found to be the most divergent among the species examined. Comparison of RFLP, RAPD, and ISSR technologies, in terms of the quantity and quality of data output, indicated that ISSRs are particularly promising for the analysis of plant genome diversity.Key words: Eleusine coracana, finger millet, genome analysis, microsatellites, randomly amplified polymorphic DNA, restriction fragment length polymorphism, simple sequence repeats.

scholarly journals Gene Discovery and Advances in Finger Millet [Eleusine coracana (L.) Gaertn.] Genomics—An Important Nutri-Cereal of Future

2016 ◽  
Vol 7 ◽  
Author(s):  
Salej Sood ◽  
Anil Kumar ◽  
B. Kalyana Babu ◽  
Vikram S. Gaur ◽  
Dinesh Pandey ◽  
...  
Keyword(s):  
Finger Millet ◽  
Gene Discovery ◽  
Eleusine Coracana
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