A feature selection method using fixed-point algorithm for DNA microarray gene expression data

2014 ◽  
Vol 18 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Alok Sharma ◽  
Kuldip K. Paliwal ◽  
Seiya Imoto ◽  
Satoru Miyano ◽  
Vandana Sharma ◽  
...  
Keyword(s):  
Gene Expression ◽  
Fixed Point ◽  
Feature Selection ◽  
Feature Selection Method ◽  
Microarray Gene Expression Data ◽  
Selection Method ◽  
Expression Data ◽  
Microarray Gene Expression ◽  
Fixed Point Algorithm ◽  
Microarray Gene

scholarly journals Microarray Gene Expression Data Classification using a Hybrid Algorithm: MRMRAGA

2019 ◽  
Vol 8 (10) ◽  
pp. 706-713
Keyword(s):  
Gene Expression ◽  
Genetic Algorithm ◽  
Feature Selection ◽  
Gene Expression Data ◽  
Feature Selection Method ◽  
Small Sample ◽  
Adaptive Genetic Algorithm ◽  
Expression Data ◽  
Microarray Gene Expression ◽  
Microarray Gene

In the field of microarray gene expression research, the high dimension of the features with a comparatively small sample size of these data became necessary for the development of a robust and efficient feature selection method in order to perform classification task more precisely on gene expression data. We propose the hybrid feature selection (mRMRAGA) approach in this paper, which combines the minimum redundancy and maximum relevance (mRMR) with the adaptive genetic algorithm (AGA). The mRMR method is frequently used to identify the characteristics more accurately for gene and its phenotypes. Then their relevance is narrowed down which is described in pairing with its relevant feature selection. This approach is known as Minimum Redundancy and Maximum Relevance. The Genetic Algorithm (GA) has been propelled with the procedure of natural selection and it is based on heuristic search method. And the adaptive genetic algorithm is improvised one which gives better performance. We have conducted an experiment on four benchmarked dataset using our proposed approach and then classified using four well-known classification approaches. The accuracy was measured and observed that it gives better performance compared to the other conventional feature selection methods.

Hybrid Feature Selection Algorithm mRMR-ICA for Cancer Classification from Microarray Gene Expression Data

2018 ◽  
Vol 21 (6) ◽  
pp. 420-430 ◽  
Author(s):  
Shuaiqun Wang ◽  
Wei Kong ◽  
Aorigele ◽  
Jin Deng ◽  
Shangce Gao ◽  
...  
Keyword(s):  
Gene Expression ◽  
Feature Selection ◽  
Gene Expression Data ◽  
Classification Accuracy ◽  
Microarray Gene Expression Data ◽  
Cancer Classification ◽  
Expression Data ◽  
Microarray Gene Expression ◽  
Redundant Genes ◽  
Microarray Gene

Aims and Objective: Redundant information of microarray gene expression data makes it difficult for cancer classification. Hence, it is very important for researchers to find appropriate ways to select informative genes for better identification of cancer. This study was undertaken to present a hybrid feature selection method mRMR-ICA which combines minimum redundancy maximum relevance (mRMR) with imperialist competition algorithm (ICA) for cancer classification in this paper. Materials and Methods: The presented algorithm mRMR-ICA utilizes mRMR to delete redundant genes as preprocessing and provide the small datasets for ICA for feature selection. It will use support vector machine (SVM) to evaluate the classification accuracy for feature genes. The fitness function includes classification accuracy and the number of selected genes. Results: Ten benchmark microarray gene expression datasets are used to test the performance of mRMR-ICA. Experimental results including the accuracy of cancer classification and the number of informative genes are improved for mRMR-ICA compared with the original ICA and other evolutionary algorithms. Conclusion: The comparison results demonstrate that mRMR-ICA can effectively delete redundant genes to ensure that the algorithm selects fewer informative genes to get better classification results. It also can shorten calculation time and improve efficiency.

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