scholarly journals Digital Therapeutics in Parkinson’s Disease: Practical Applications and Future Potential

2021 ◽  
pp. 1-7
Author(s):  
Terry D. Ellis ◽  
Gammon M. Earhart
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Healthy Lifestyle ◽  
Modern Technology ◽  
Self Management ◽  
Lifestyle Behaviors ◽  
Practical Applications ◽  
Barriers To Access ◽  
Future Potential ◽  
Interdisciplinary Interventions

Digital therapeutics, treatments delivered remotely and enabled by modern technology, facilitate the provision of personalized, evidence-based, interdisciplinary interventions to manage the complexities associated with Parkinson’s disease. In the context of the COVID-19 pandemic, the need for digital therapeutics has arguably never been greater. However, despite new advances in technology and a heightened interest due to the pandemic, digital therapeutics remain underdeveloped and underutilized. In this paper, we briefly review practical applications and emerging advances in digital therapeutic platforms that target motor and non-motor signs and healthy lifestyle behaviors such as regular exercise, a healthy diet and optimal sleep hygiene habits. Future applications which could transform personalized self-management and patient care are presented. Opportunities, drawbacks and barriers to access are discussed.

scholarly journals Nonpharmacological Modulation of Chronic Inflammation in Parkinson’s Disease: Role of Diet Interventions

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Stefania Kalampokini ◽  
Anouck Becker ◽  
Klaus Fassbender ◽  
Epameinondas Lyros ◽  
Marcus M. Unger
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Chronic Inflammation ◽  
Healthy Lifestyle ◽  
Future Research ◽  
Dietary Interventions ◽  
Lifestyle Modifications ◽  
Proinflammatory Response ◽  
Beneficial Effects ◽  
Mediators Of Inflammation

Neuroinflammation is increasingly recognized as an important pathophysiological feature of neurodegenerative diseases such as Parkinson’s disease (PD). Recent evidence suggests that neuroinflammation in PD might originate in the intestine and the bidirectional communication between the central and enteric nervous system, the so-called “gut-brain axis,” has received growing attention due to its contribution to the pathogenesis of neurological disorders. Diet targets mediators of inflammation with various mechanisms and combined with dopaminergic treatment can exert various beneficial effects in PD. Food-based therapies may favorably modulate gut microbiota composition and enhance the intestinal epithelial integrity or decrease the proinflammatory response by direct effects on immune cells. Diets rich in pre- and probiotics, polyunsaturated fatty acids, phenols including flavonoids, and vitamins, such as the Mediterranean diet or a plant-based diet, may attenuate chronic inflammation and positively influence PD symptoms and even progression of the disease. Dietary strategies should be encouraged in the context of a healthy lifestyle with physical activity, which also has neuroimmune-modifying properties. Thus, diet adaptation appears to be an effective additive, nonpharmacological therapeutic strategy that can attenuate the chronic inflammation implicated in PD, potentially slow down degeneration, and thereby modify the course of the disease. PD patients should be highly encouraged to adopt corresponding lifestyle modifications, in order to improve not only PD symptoms, but also general quality of life. Future research should focus on planning larger clinical trials with dietary interventions in PD in order to obtain hard evidence for the hypothesized beneficial effects.

Factors supporting self-management in Parkinson’s disease: implications for nursing practice

2008 ◽  
Vol 3 (3) ◽  
pp. 187-193 ◽  
Author(s):  
Lynn Chenoweth ◽  
Robyn Gallagher ◽  
June N. Sheriff ◽  
Judith Donoghue ◽  
Jane Stein-Parbury
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Nursing Practice ◽  
Self Management

Nursing Research in Parkinson’s Disease From 2006 to 2015

2016 ◽  
Vol 26 (2) ◽  
pp. 142-156 ◽  
Author(s):  
Ju Young Shin ◽  
Barbara Habermann
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Family Caregiving ◽  
Symptom Management ◽  
Family Members ◽  
Theoretical Models ◽  
Self Management ◽  
Nursing Research

Most people with Parkinson’s disease (PD) reside in their homes with their family members. Nurses are in a good position to partner with people with PD and their family members for better self-management of the disease and improved quality of life. The purpose of this systematic review was to assess the state of the science of nursing research related to PD during the 10-year period, 2006 to 2015. A total of 27 studies were included in this review. Family caregiving was the most studied topic, followed by symptom management/medication adherence, quality of life, end-of-life/palliative care, and functional status/improving function. Recommendations for future studies in PD include (a) developing and testing interventions based on theoretical models in the areas of self-management, symptom management, and function improvement in people with PD and for caregivers caring for people with advanced stage PD, and (b) building programs of research with interprofessional teams.

scholarly journals Acceptability and practicability of self-management for patients with Parkinson's disease based on smartphone applications in China

2019 ◽  
Author(s):  
Jie Hu ◽  
Dezhi Yuan ◽  
Qiuye Zhao ◽  
Xuefei Wang ◽  
Xiaotian Zhang ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Chronic Condition ◽  
Positive Attitude ◽  
Medication Compliance ◽  
Self Management ◽  
Smartphone Apps ◽  
Smartphone Applications ◽  
Promising Strategy ◽  
Initial Stage

Abstract Background China has had about 1.2 billion mobile-phone users, and usage continues to grow. However, mobile-health services (mHealth) are currently in the initial stage, and have not yet prevailed in China. Additionally, the prevalence of Parkinson's disease (PD) in China is 190/100,000. Indeed, these PD patients would benefit from mHealth to manage their disease. Therefore, we designed a study to determine attitudes toward smartphone applications (apps) for chronic condition self-management, and to discover the practicality of these apps among PD patients in China.Methods We selected 204 participants with PD between 52 and 87 years old and surveyed their attitudes concerning the use of smartphone apps for chronic condition management via questionnaires.Results Among the participants, 65.19％ had smartphones. Among these smartphone users, 82.84％ expressed a preference for using apps for PD management. This group tended to be younger and more frequent web users with higher education and better medication compliance, and they tended to have a longer PD course and worse conditions (P < 0.001, P = 0.001, P < 0.001, P = 0.041, P < 0.001, P = 0.013.) Additionally, the willingness to apply apps for PD self-management was positively related to education (P < 0.001) and negatively related to age and PD course (P = 0.017, P < 0.001).Conclusion In China, patients with PD have a generally positive attitude towards self-management through smartphone apps. Consequently, improving the coverage of smartphones with practical and handy apps is a promising strategy for PD self-management.

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