scholarly journals Glutathione loaded solid lipid nanoparticles: Preparation and in vitro evaluation as delivery systems of the antioxidant peptide to immunocompetent fish cells

2016 ◽  
Vol 2 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Adriana Trapani ◽  
Giuseppe Tripodo ◽  
Delia Mandracchia ◽  
Nicola Cioffi ◽  
Nicoletta Ditaranto ◽  
...  
Keyword(s):  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Delivery Systems ◽  
Antioxidant Peptide ◽  
In Vitro Evaluation ◽  
Solid Lipid ◽  
Fish Cells

scholarly journals In vitro Evaluation of Mannosylated Paromomycin-Loaded Solid Lipid Nanoparticles on Acute Toxoplasmosis

2020 ◽  
Vol 10 ◽  
Author(s):  
Mojdeh Khosravi ◽  
Hanieh Mohammad Rahimi ◽  
Delaram Doroud ◽  
Elnaz Sadat Mirsamadi ◽  
Hamed Mirjalali ◽  
...  
Keyword(s):  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
In Vitro Evaluation ◽  
Solid Lipid ◽  
Acute Toxoplasmosis

Preparation, Characterization, and In vitro Evaluation of Curcumin- and Resveratrol-Loaded Solid Lipid Nanoparticles

2019 ◽  
Vol 20 (4) ◽  
Author(s):  
Ashwini Gumireddy ◽  
Ryann Christman ◽  
Dunesh Kumari ◽  
Amit Tiwari ◽  
E. Jeffrey North ◽  
...  
Keyword(s):  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
In Vitro Evaluation ◽  
Solid Lipid

scholarly journals Development of Solid Lipid Nanoparticles by Cold Dilution of Microemulsions: Curcumin Loading, Preliminary In Vitro Studies, and Biodistribution

Nanomaterials ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 230 ◽  
Author(s):  
Daniela Chirio ◽  
Elena Peira ◽  
Chiara Dianzani ◽  
Elisabetta Muntoni ◽  
Casimiro Gigliotti ◽  
...  
Keyword(s):  
Chemical Stability ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Delivery Systems ◽  
Dependent Manner ◽  
Solid Lipid ◽  
Cytotoxicity Studies ◽  
Over Time

Background: Solid lipid nanoparticles (SLNs) are attractive drug delivery systems for lipophilic molecules like curcumin (CURC) with low chemical stability. Methods: A simple, innovative, and cold-operating method, named “cold dilution of microemulsion” is developed by the authors to produce SLNs. An oil-in-water microemulsion (µE), whose disperse phase consisted of a solution of trilaurin in a partially water-miscible solvent, was prepared after mutually saturating solvent and water. Trilaurin SLNs precipitated following solvent removal upon water dilution of the µE. After SLN characterization (mean size, Zeta potential, CURC entrapment efficiency, and over time stability), they were tested for in vitro cytotoxicity studies on pancreatic adenocarcinoma cell lines and for in vivo preliminary biodistribution studies in Wistar healthy rats. Results: CURC loaded SLNs (SLN-CURC) had mean diameters around 200 nm, were negatively charged, stable over time, and able to entrap CURC up to almost 90%, consequently improving its stability. SLN-CURC inhibited in vitro pancreatic carcinoma cell growth in concentration-dependent manner. Their in vivo intravenous administration suggested a possible long circulation. Conclusions: These results, according to a concomitant study on chitosan-coated SLNs, confirm the possibility to apply the developed SLN-based delivery systems as a means to entrap CURC, to improve both its water dispersibility and chemical stability, facilitating its application in therapy.

scholarly journals Design, characterization and in vitro evaluation of linalool-loaded solid lipid nanoparticles as potent tool in cancer therapy

2017 ◽  
Vol 154 ◽  
pp. 123-132 ◽  
Author(s):  
Boris Rodenak-Kladniew ◽  
German A. Islan ◽  
Margarita G. de Bravo ◽  
Nelson Durán ◽  
Guillermo R. Castro
Keyword(s):  
Cancer Therapy ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
In Vitro Evaluation ◽  
Solid Lipid

scholarly journals In vitro evaluation of chloroquine-loaded and heparin surface-functionalized solid lipid nanoparticles

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Joseph O. Muga ◽  
Jeremiah W. Gathirwa ◽  
Matshawandile Tukulula ◽  
Walter G. Z. O. Jura
Keyword(s):  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
In Vitro Evaluation ◽  
Solid Lipid

scholarly journals Indomethacin-Loaded Solid Lipid Nanoparticles for Ocular Delivery: Development, Characterization, and In Vitro Evaluation

2013 ◽  
Vol 29 (2) ◽  
pp. 216-228 ◽  
Author(s):  
Ketan Hippalgaonkar ◽  
Goutham R. Adelli ◽  
Kanchan Hippalgaonkar ◽  
Michael A. Repka ◽  
Soumyajit Majumdar
Keyword(s):  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Ocular Delivery ◽  
In Vitro Evaluation ◽  
Solid Lipid
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