Cell Signaling Pathways and Iron Chelation in the Neurorestorative Activity of Green Tea Polyphenols: Special Reference to Epigallocatechin Gallate (EGCG)

2008 ◽  
Vol 15 (2) ◽  
pp. 211-222 ◽  
Author(s):  
Silvia A. Mandel ◽  
Tamar Amit ◽  
Limor Kalfon ◽  
Lydia Reznichenko ◽  
Orly Weinreb ◽  
...  
Keyword(s):  
Cell Signaling ◽  
Special Reference ◽  
Signaling Pathways ◽  
Green Tea ◽  
Epigallocatechin Gallate ◽  
Iron Chelation ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Cell Signaling Pathways

Separation of epigallocatechin gallate and epicatechin gallate from tea polyphenols by macroporous resin and crystallization

2021 ◽  
Author(s):  
Li Wang ◽  
Xin Huang ◽  
Huijuan Jing ◽  
Xin Ye ◽  
Chao Jiang ◽  
...  
Keyword(s):  
Green Tea ◽  
Epigallocatechin Gallate ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Macroporous Resin ◽  
Epicatechin Gallate

Epigallocatechin gallate (EGCG) and epicatechin gallate (ECG) are the most abundant ester catechins of green tea polyphenols (GTPs) with numerous potential bioactivities, which have a wide application prospect in the...

scholarly journals Epigallocatechin Gallate (EGCG), a Green Tea Polyphenol, Reduces Coronavirus Replication in a Mouse Model

Viruses ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2533
Author(s):  
Rackhyun Park ◽  
Minsu Jang ◽  
Yea-In Park ◽  
Yeonjeong Park ◽  
Woochul Jung ◽  
...  
Keyword(s):  
Mouse Model ◽  
Green Tea ◽  
Particle Production ◽  
Epigallocatechin Gallate ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Tea Polyphenol ◽  
Green Tea Polyphenol

The COVID-19 pandemic has resulted in a huge number of deaths from 2020 to 2021; however, effective antiviral drugs against SARS-CoV-2 are currently under development. Recent studies have demonstrated that green tea polyphenols, particularly EGCG, inhibit coronavirus enzymes as well as coronavirus replication in vitro. Herein, we examined the inhibitory effect of green tea polyphenols on coronavirus replication in a mouse model. We used epigallocatechin gallate (EGCG) and green tea polyphenols containing more than 60% catechin (GTP60) and human coronavirus OC43 (HCoV-OC43) as a surrogate for SARS-CoV-2. Scanning electron microscopy analysis results showed that HCoV-OC43 infection resulted in virion particle production in infected cells. EGCG and GTP60 treatment reduced coronavirus protein and virus production in the cells. Finally, EGCG- and GTP60-fed mice exhibited reduced levels of coronavirus RNA in mouse lungs. These results demonstrate that green tea polyphenol treatment is effective in decreasing the level of coronavirus in vivo.

scholarly journals Prospective randomized trial evaluating blood and prostate tissue concentrations of green tea polyphenols and quercetin in men with prostate cancer

2020 ◽  
Vol 11 (5) ◽  
pp. 4114-4122
Author(s):  
Susanne M. Henning ◽  
Piwen Wang ◽  
Ru-Po Lee ◽  
Amy Trang ◽  
George Husari ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Randomized Trial ◽  
Green Tea ◽  
Epigallocatechin Gallate ◽  
Potential Effect ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Prostate Tissue ◽  
Epicatechin Gallate ◽  
Tissue Concentrations

Epigallocatechin gallate, epicatechin gallate (Green Tea Polyphenols – GTPs) and quercetin (Q) were taken up in prostate tissue after Q and GTP consumption. Our findings herein suggest a potential effect of Q on GTP metabolism.

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