Expression of Microtubule Associated Protein Tau in Mouse Pancreatic Islets Is Restricted to Autonomic Nerve Fibers

2020 ◽  
Vol 75 (4) ◽  
pp. 1339-1349 ◽  
Author(s):  
Ranran Zhou ◽  
Wen Hu ◽  
Chun-Ling Dai ◽  
Cheng-Xin Gong ◽  
Khalid Iqbal ◽  
...  
Keyword(s):  
Pancreatic Islets ◽  
Nerve Fibers ◽  
Autonomic Nerve ◽  
Protein Tau ◽  
Microtubule Associated Protein Tau ◽  
Mouse Pancreatic Islets

Innervation of endoneurial microvessels in human sural nerve

1992 ◽  
Vol 50 (1) ◽  
pp. 920-921
Author(s):  
John L. Beggs ◽  
Peter C. Johnson ◽  
Astrid G. Olafsen ◽  
C. Jane Watkins
Keyword(s):  
Blood Flow ◽  
Blood Vessels ◽  
Blood Supply ◽  
Peripheral Nerves ◽  
Sural Nerve ◽  
Nerve Fibers ◽  
Arterial Supply ◽  
Autonomic Nerve ◽  
Vasa Nervorum ◽  
Endoneurial Blood Flow

The blood supply (vasa nervorum) to peripheral nerves is composed of an interconnected dual circulation. The endoneurium of nerve fascicles is maintained by the intrinsic circulation which is composed of microvessels primarily of capillary caliber. Transperineurial arterioles link the intrinsic circulation with the extrinsic arterial supply located in the epineurium. Blood flow in the vasa nervorum is neurogenically influenced (1,2). Although a recent hypothesis proposes that endoneurial blood flow is controlled by the action of autonomic nerve fibers associated with epineurial arterioles (2), our recent studies (3) show that in addition to epineurial arterioles other segments of the vasa nervorum are also innervated. In this study, we examine blood vessels of the endoneurium for possible innervation.

Slow [Ca2+]i oscillations induced by ketoisocaproate in single mouse pancreatic islets

Diabetes ◽  
1995 ◽  
Vol 44 (3) ◽  
pp. 300-305 ◽  
Author(s):  
F. Martin ◽  
J. V. Sanchez-Andres ◽  
B. Soria
Keyword(s):  
Pancreatic Islets ◽  
Mouse Pancreatic Islets

scholarly journals MELANOPHORE BANDS AND AREAS DUE TO NERVE CUTTING, IN RELATION TO THE PROTRACTED ACTIVITY OF NERVES

1941 ◽  
Vol 24 (4) ◽  
pp. 483-504 ◽  
Author(s):  
G. H. Parker
Keyword(s):  
Pituitary Gland ◽  
Olive Oil ◽  
Magnesium Sulfate ◽  
Nerve Fibers ◽  
Autonomic Nerve ◽  
Color Changes ◽  
The Third ◽  
Limited Degree ◽  
Adrenergic Fibers

1. When appropriate chromatic nerves are cut caudal bands, cephalic areas, and the pelvic fins of the catfish Ameiurus darken. In pale fishes all these areas will sooner or later blanch. By recutting their nerves all such blanched areas will darken again. 2. These observations show that the darkening of caudal bands, areas, and fins on cutting their nerves is not due to paralysis (Brücke), to the obstruction of central influences such as inhibition (Zoond and Eyre), nor to vasomotor disturbances (Hogben), but to activities emanating from the cut itself. 3. The chief agents concerned with the color changes in Ameiurus are three: intermedin from the pituitary gland, acetylcholine from the dispersing nerves (cholinergic fibers), and adrenalin from the concentrating nerves (adrenergic fibers). The first two darken the fish; the third blanches it. In darkening the dispersing nerves appear to initiate the process and to be followed and substantially supplemented by intermedin. 4. Caudal bands blanch by lateral invasion, cephalic areas by lateral invasion and internal disintegration, and pelvic fins by a uniform process of general loss of tint equivalent to internal disintegration. 5. Adrenalin may be carried in such an oil as olive oil and may therefore act as a lipohumor; it is soluble in water and hence may act as a hydrohumor. In lateral invasion (caudal bands, cephalic areas) it probably acts as a lipohumor and in internal disintegration (cephalic areas, pelvic fins) it probably plays the part of a hydrohumor. 6. The duration of the activity of dispersing nerves after they had been cut was tested by means of the oscillograph, by anesthetizing blocks, and by cold-blocks. The nerves of Ameiurus proved to be unsatisfactory for oscillograph tests. An anesthetizing block, magnesium sulfate, is only partly satisfactory. A cold-block, 0°C., is successful to a limited degree. 7. By means of a cold-block it can be shown that dispersing autonomic nerve fibers in Ameiurus can continue in activity for at least 6½ hours. It is not known how much longer they may remain active. So far as the duration of their activity is concerned dispersing nerve fibers in this fish are unlike other types of nerve fibers usually studied.

scholarly journals Oligomerization of the microtubule-associated protein tau is mediated by its N-terminal sequences: implications for normal and pathological tau action

2016 ◽  
Vol 137 (6) ◽  
pp. 939-954 ◽  
Author(s):  
H. Eric Feinstein ◽  
Sarah J. Benbow ◽  
Nichole E. LaPointe ◽  
Nirav Patel ◽  
Srinivasan Ramachandran ◽  
...  
Keyword(s):  
Protein Tau ◽  
Microtubule Associated Protein Tau
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