scholarly journals Erlangen Score Predicts Cognitive and Neuroimaging Progression in Mild Cognitive Impairment Stage of Alzheimer’s Disease

2019 ◽  
Vol 69 (2) ◽  
pp. 551-559
Author(s):  
Tobias Skillbäck ◽  
Johannes Kornhuber ◽  
Kaj Blennow ◽  
Henrik Zetterberg ◽  
Piotr Lewczuk ◽  
...  
2001 ◽  
Vol 172 (2) ◽  
pp. 433-436 ◽  
Author(s):  
Masahiro Maruyama ◽  
Hiroyuki Arai ◽  
Mitsunori Sugita ◽  
Haruko Tanji ◽  
Makoto Higuchi ◽  
...  

Brain ◽  
2015 ◽  
Vol 138 (5) ◽  
pp. 1327-1338 ◽  
Author(s):  
Stephanie J. B. Vos ◽  
Frans Verhey ◽  
Lutz Frölich ◽  
Johannes Kornhuber ◽  
Jens Wiltfang ◽  
...  

Author(s):  
John T. O’Brien ◽  
Louise Grayson

Mild cognitive impairment is a term used to describe a condition or conditions where subjects have recognisable degrees of objective cognitive impairment which fall short of current standardised definitions for either a dementia syndrome in general, or for particular disorders such as Alzheimer’s disease, dementia with Lewy bodies or frontotemporal dementia. This chapter summarises some of the key issues surrounding the historical development of pre-dementia syndromes, considers the conceptual issues related to the use of the term mild cognitive impairment as a diagnosis, summarises what is known regarding epidemiology, clinical features, pathophysiology, prognosis, therapeutics and outlines current clinical practice in the area. The chapter concludes with a review of recent research developments and looks at the new diagnostic criteria, in particular the potential use of biomarkers to allow diagnosis of Alzheimer’s disease (AD) at an early, or mild cognitive impairment, stage.


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