scholarly journals The Role of Lifestyle Factors and Sleep Duration for Late-Onset Dementia: A Cohort Study

2018 ◽  
Vol 66 (2) ◽  
pp. 579-586 ◽  
Author(s):  
Susanna C. Larsson ◽  
Alicja Wolk
Keyword(s):  
Cohort Study ◽  
Sleep Duration ◽  
Late Onset ◽  
Lifestyle Factors ◽  
Late Onset Dementia

The plasticity of late‐onset dementia: A nationwide cohort study in Denmark

2021 ◽  
Author(s):  
Emilie R. Hegelund ◽  
Amar J. Mehta ◽  
Laust H. Mortensen ◽  
Rudi G. J. Westendorp
Keyword(s):  
Cohort Study ◽  
Late Onset ◽  
Late Onset Dementia

scholarly journals Lifestyle factors and reversion to normoglycaemia by prediabetes type in PREDAPS study.

2019 ◽  
Author(s):  
LUCIA CEA SORIANO ◽  
Carolina Giráldez-García ◽  
Romana Albadalejo ◽  
Josep Franch-Nadal ◽  
Manel Mata-Cases ◽  
...  
Keyword(s):  
Cohort Study ◽  
Healthy Lifestyle ◽  
Lifestyle Factors ◽  
Glucose Regulation ◽  
Lifestyle Factor ◽  
Observational Prospective Cohort Study ◽  
Normal Glucose ◽  
Normal Glucose Regulation ◽  
Relationship Of

Abstract Background There is little evidence on how healthy lifestyle factors can explain the variation in the proportion of patients reverting to normal glucose regulation according to type of prediabetesAims To study the role of lifestyle factors on the reversion to normal glucose regulation according to type of prediabetes.Design and Setting Observational prospective cohort study. The Cohort study in Primary Health Care on the Evolution of Patients with Prediabetes from2012-2015Methods Participants were classified, according to the definition established by ADA using either fasting plasma glucose (FPG) levels between 100-125 mg/dL or HbA1c between 39-47 mmol/mol (5.7%–6.4%), in three groups. Reversion to normal glucose regulation was calculated at third year of follow-up. Relationship of lifestyle factor and type of prediabetes with reversion was estimated by means of Odds Ratios (OR) using three sequential models.Results Proportion of reversion rates were 31% for FPG group, 31% for HbA1c group and 7.9% for both altered parameters group, respectively. BMI<25 kg/m2[OR (95% CI): 1.90 (1.20-3.01)], high adherence to Mediterranean diet 1.78 (1.21-2.63) and absence of abdominal obesity 1.70 (1.19-2.43) were the strongest lifestyle predictors for reversion. Compared with those with both altered parameters, OR of reversion of prediabetes was 4.87 (3.10-7.65) for FPG group and 3.72 (2.39-5.78) for HbA1c group. These estimates remained almost the same after further adjustment for biochemical parameters and lifestyle factors.Conclusions Although optimal lifestyle factors showed to be a positive predictor, those do not seem to explain the differences according to the type of prediabetes.

scholarly journals Lifestyle factors and reversion to normoglycaemia by prediabetes type in PREDAPS study.

2020 ◽  
Author(s):  
Carolina Giráldez-García ◽  
LUCIA CEA SORIANO ◽  
Romana Albadalejo ◽  
Josep Franch-Nadal ◽  
Manel Mata-Cases ◽  
...  
Keyword(s):  
Cohort Study ◽  
Biochemical Parameters ◽  
Healthy Lifestyle ◽  
Lifestyle Factors ◽  
Glucose Regulation ◽  
Lifestyle Factor ◽  
Normal Glucose ◽  
Normal Glucose Regulation ◽  
Healthy Lifestyle Interventions

Abstract Background: Healthy lifestyle interventions and drug therapies are proven to have a positive preventative influence on normal glucose regulation in prediabetes; however, there is little evidence to support the role of these factors according to the various stage of the prediabetes stateAims: This study aims to investigate the role of lifestyle factors on the reversion to normal glucose regulation according to the different stage of the prediabetes state based on most up-to-date American Diabetes Association (ADA) guidelines.Design and Setting: Observational prospective cohort study. The Cohort study in Primary Health Care on the Evolution of Patients with Prediabetes from 2012-2015Methods: A total of 1184 individuals aged 30 to 74 years old were included and classified based on the ADA in three mutually exclusive groups using either fasting plasma glucose (FPG) levels (from 100-125 mg/dl, FPG group), HbA1c (5.7%–6.4%, HbA1c group) or both impaired parameters group. Information on lifestyle factors and biochemical parameters were collected at baseline Reversion to normal glucose regulation was calculated at third year of follow-up. Relationship of lifestyle factor and type of prediabetes with reversion were estimated using odds ratios (ORs) with 95% confidence intervals (CIs) adjusting by different groups of confounders.Results: Proportion of reversion rates were 31% for FPG group, 31% for HbA1c group and 7.9% for both altered parameters group, respectively. Optimal life style factors such as BMI<25 kg/m2[OR (95% CI): 1.90 (1.20-3.01)], high adherence to Mediterranean diet 1.78 (1.21-2.63) and absence of abdominal obesity 1.70 (1.19-2.43) were the strongest predictors for reversion to normal glucose. ORs of reversion to normal glucose were 4.87 (3.10-7.65) for FPG group and 3.72 (2.39-5.78) for HbA1c group, taking as reference those with both impaired parameters. These estimates remained almost the same after further adjustment for biochemical parameters and lifestyle factors.Conclusions: Although optimal lifestyle factors showed to be a positive predictor for reversion to normal glucose regulation, they do not seem to explain the differences according to the type of prediabetes.

scholarly journals 206 - Suicide and euthanasia in young onset dementia

2020 ◽  
Vol 32 (S1) ◽  
pp. 42-42
Keyword(s):  
Suicide Ideation ◽  
Late Onset ◽  
Brain Disorders ◽  
Life Situation ◽  
Young Onset ◽  
Great Transformation ◽  
Young Onset Dementia ◽  
Scientific Purpose ◽  
Late Onset Dementia

BackgroundDementia affects people that have not reached the age of 65 years. Persons diagnosed with dementia before this age, are often referred to as people with “young onset dementia". They are normally diagnosed in a later stage of the disorder compared to their older peers. This, probably due to a larger variety of brain disorders causing dementia among young persons compared to what is the case among elderly. People with young onset dementia experience a great transformation of existential life. Studies have shown that they are more aware of the disease and depressed than people with late onset dementia. The awareness of disease increases the risk of suicide ideation in this population. Health personnel should therefore be more trained to detect and diagnose young persons with dementia at an earlier stage, to meet their needs. Providing tailored services to them and their families may contribute to prevent suicide and adequately address thoughts about ending life.Content of the SessionWe will organize four lectures with speakers from Brazil, Norway, the Netherlands and Portugal. The first lecture will contain results focusing on awareness of the disease and suicide ideation and the different awareness between persons with young onset of dementia and late onset dementia. The second and third lecture will report results from two qualitative studies, in which young persons with dementia have been interviewed express ideas about suicide and end of life. The last one will build on a case report to discuss the role of family interventions in the clinical context of YOD, including scenarios involving including scenarios involving suicidality and challenges related with the legalization of euthanasia.Scientific PurposeTo contribute to the development of knowledge and understanding of the situation of young persons with dementia and their life situation based on three scientific studies and a clinically based discussion of the topic.

scholarly journals Lifestyle factors and reversion to normoglycaemia by prediabetes type in PREDAPS study.

2020 ◽  
Author(s):  
LUCIA CEA SORIANO ◽  
Carolina Giráldez-García ◽  
Romana Albadalejo ◽  
Josep Franch-Nadal ◽  
Manel Mata-Cases ◽  
...  
Keyword(s):  
Cohort Study ◽  
Biochemical Parameters ◽  
Healthy Lifestyle ◽  
Lifestyle Factors ◽  
Glucose Regulation ◽  
Lifestyle Factor ◽  
Normal Glucose ◽  
Normal Glucose Regulation ◽  
Healthy Lifestyle Interventions

Abstract Background: Healthy lifestyle interventions and drug therapies are proven to have a positive preventative influence on normal glucose regulation in prediabetes; however, there is little evidence to support the role of these factors according to the various stage of the prediabetes state. Aims : This study aims to investigate the role of lifestyle factors on the reversion to normal glucose regulation according to the different stage of the prediabetes state based on most up-to-date American Diabetes Association (ADA) guidelines. Design and Setting: Observational prospective cohort study. The Cohort study in Primary Health Care on the Evolution of Patients with Prediabetes from 2012-2015 Methods: A total of 1184 individuals aged 30 to 74 years old were included and classified based on the ADA in three mutually exclusive groups using either fasting plasma glucose (FPG) levels (from 100-125 mg/dl, FPG group), (HbA 1c (5.7%–6.4%, HbA1c group) or both impaired parameters group. Information on lifestyle factors and biochemical parameters were collected at baseline Reversion to normal glucose regulation was calculated at third year of follow-up. Relationship of lifestyle factor and type of prediabetes with reversion were estimated using odds ratios (ORs) with 95% confidence intervals (CIs) adjusting by different groups of confounders. Results: Proportion of reversion rates were 31% for FPG group, 31% for HbA1c group and 7.9% for both altered parameters group, respectively. Optimal life style factors such as BMI<25 kg/m 2 [OR (95% CI): 1.90 (1.20-3.01)], high adherence to Mediterranean diet 1.78 (1.21-2.63) and absence of abdominal obesity 1.70 (1.19-2.43) were the strongest predictors for reversion to normal glucose. ORs of reversion to normal glucose were 4.87 (3.10-7.65) for FPG group and 3.72 (2.39-5.78) for HbA1c group, taking as reference those with both impaired parameters. These estimates remained almost the same after further adjustment for biochemical parameters and lifestyle factors. Conclusions: Although optimal lifestyle factors showed to be a positive predictor for reversion to normal glucose regulation, they do not seem to explain the differences according to the type of prediabetes.

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