scholarly journals Preservation of Musical Memory Throughout the Progression of Alzheimer’s Disease? Toward a Reconciliation of Theoretical, Clinical, and Neuroimaging Evidence

2019 ◽  
Vol 68 (3) ◽  
pp. 857-883 ◽  
Author(s):  
Mathilde Groussard ◽  
Tyler G. Chan ◽  
Renaud Coppalle ◽  
Hervé Platel
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Musical Memory

scholarly journals The functional neuroanatomy of musical memory in Alzheimer's disease

Cortex ◽  
2019 ◽  
Vol 115 ◽  
pp. 357-370 ◽  
Author(s):  
Catherine F. Slattery ◽  
Jennifer L. Agustus ◽  
Ross W. Paterson ◽  
Oliver McCallion ◽  
Alexander J.M. Foulkes ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Functional Neuroanatomy ◽  
Musical Memory

scholarly journals Preservation of musical memory in Alzheimer's disease.

1989 ◽  
Vol 52 (12) ◽  
pp. 1415-1416 ◽  
Author(s):  
H A Crystal ◽  
E Grober ◽  
D Masur
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Musical Memory

scholarly journals Why musical memory can be preserved in advanced Alzheimer’s disease

Brain ◽  
2015 ◽  
Vol 138 (8) ◽  
pp. 2438-2450 ◽  
Author(s):  
Jörn-Henrik Jacobsen ◽  
Johannes Stelzer ◽  
Thomas Hans Fritz ◽  
Gael Chételat ◽  
Renaud La Joie ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Musical Memory

scholarly journals [P-166]: Preservation of episodic and semantic musical memory in severe Alzheimer's disease

2005 ◽  
Vol 1 ◽  
pp. S62-S62
Author(s):  
Luis Fornazzari ◽  
Tonya Castle ◽  
Shailesh Nadkarni ◽  
Dielle Miranda ◽  
Nina Apanasiewicz ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Musical Memory

Episodic and Semantic Memory for Melodies in Alzheimer's Disease

2012 ◽  
Vol 29 (5) ◽  
pp. 501-507 ◽  
Author(s):  
Ashley D. Vanstone ◽  
Ritu Sikka ◽  
Leila Tangness ◽  
Rosalind Sham ◽  
Angeles Garcia ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Episodic Memory ◽  
Semantic Memory ◽  
Memory Task ◽  
Younger Adults ◽  
The Difference ◽  
Novel Target ◽  
Musical Memory

the present study addressed episodic and semantic memory for melodies in three groups of participants: 35 younger adults, 40 older adults, and 10 individuals with mild to moderate Alzheimer's disease (AD). To assess episodic memory, a study list of eight novel target melodies was presented three times, followed by a test trial in which target melodies were mixed with foil (previously unheard) melodies. Both explicit and implicit measures were obtained. Explicit memory was assessed by the accuracy of discrimination of the target melodies from the foils. Younger adults were significantly more accurate than older adults, who in turn had significantly higher scores than AD adults. Implicit memory was assessed by examining the difference in pleasantness ratings between target and foil melodies. Younger adults showed significantly greater differences in pleasantness ratings than older adults and AD adults; scores for the two latter groups did not differ. To assess semantic memory, participants were asked to identify traditional melodies within a series of traditional and novel melodies. In contrast to the episodic memory results, all three groups showed very high scores on the semantic memory task with no significant differences among groups. The results support the notion that, though other forms of musical memory may be compromised, semantic memory for melody may be preserved in normal aging and in AD.

Cognitive control constrains memory attributions

2019 ◽  
Vol 42 ◽  
Author(s):  
Colleen M. Kelley ◽  
Larry L. Jacoby
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Control

Abstract Cognitive control constrains retrieval processing and so restricts what comes to mind as input to the attribution system. We review evidence that older adults, patients with Alzheimer's disease, and people with traumatic brain injury exert less cognitive control during retrieval, and so are susceptible to memory misattributions in the form of dramatic levels of false remembering.

Formation of paired helical filaments in Alzheimer's disease

1984 ◽  
Vol 42 ◽  
pp. 302-303
Author(s):  
J. Metuzals ◽  
D. F. Clapin ◽  
V. Montpetit
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Frontal Lobe ◽  
Giant Axon ◽  
Paired Helical Filaments ◽  
Normal Brain ◽  
Protein Assemblies ◽  
Electron Microscopic ◽  
Helical Symmetry ◽  
Structural Levels

Information on the conformation of paired helical filaments (PHF) and the neurofilamentous (NF) network is essential for an understanding of the mechanisms involved in the formation of the primary lesions of Alzheimer's disease (AD): tangles and plaques. The structural and chemical relationships between the NF and the PHF have to be clarified in order to discover the etiological factors of this disease. We are investigating by stereo electron microscopic and biochemical techniques frontal lobe biopsies from patients with AD and squid giant axon preparations. The helical nature of the lesion in AD is related to pathological alterations of basic properties of the nervous system due to the helical symmetry that exists at all hierarchic structural levels in the normal brain. Because of this helical symmetry of NF protein assemblies and PHF, the employment of structure reconstruction techniques to determine the conformation, particularly the handedness of these structures, is most promising. Figs. 1-3 are frontal lobe biopsies.

Computer-aided methods for 3-D visualization of serial sections and thick biological specimens

1992 ◽  
Vol 50 (2) ◽  
pp. 1060-1061
Author(s):  
Mark Ellisman ◽  
Maryann Martone ◽  
Gabriel Soto ◽  
Eleizer Masliah ◽  
David Hessler ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Three Dimensional ◽  
Neuritic Plaque ◽  
Dimensional Structure ◽  
Data Sets ◽  
Molecular Physiology ◽  
Research Activities ◽  
Computer Aided ◽  
Dimensional Reconstruction

Structurally-oriented biologists examine cells, tissues, organelles and macromolecules in order to gain insight into cellular and molecular physiology by relating structure to function. The understanding of these structures can be greatly enhanced by the use of techniques for the visualization and quantitative analysis of three-dimensional structure. Three projects from current research activities will be presented in order to illustrate both the present capabilities of computer aided techniques as well as their limitations and future possibilities.The first project concerns the three-dimensional reconstruction of the neuritic plaques found in the brains of patients with Alzheimer's disease. We have developed a software package “Synu” for investigation of 3D data sets which has been used in conjunction with laser confocal light microscopy to study the structure of the neuritic plaque. Tissue sections of autopsy samples from patients with Alzheimer's disease were double-labeled for tau, a cytoskeletal marker for abnormal neurites, and synaptophysin, a marker of presynaptic terminals.

Sign in / Sign up

Export Citation Format

Share Document