Age-Related Changes in the Spatial Frequency Threshold of Male and Female 3xTg-AD Mice Using OptoMotry

2018 ◽  
Vol 62 (2) ◽  
pp. 591-596 ◽  
Author(s):  
Jillian L. King ◽  
Aimée A. Wong ◽  
Richard E. Brown
Keyword(s):  
Spatial Frequency ◽  
Male And Female ◽  
Age Related ◽  
Frequency Threshold ◽  
Age Related Changes

Age-related changes in ischemic tolerance in male and female mouse hearts

2005 ◽  
Vol 38 (2) ◽  
pp. 245-256 ◽  
Author(s):  
L WILLEMS ◽  
A ZATTA ◽  
K HOLMGREN ◽  
K ASHTON ◽  
J HEADRICK
Keyword(s):  
Female Mouse ◽  
Ischemic Tolerance ◽  
Male And Female ◽  
Age Related ◽  
Age Related Changes

Age-related changes in the carcass yield and meat quality of male and female nutrias ( Myocastor coypus ) under intensive production system

Meat Science ◽  
2017 ◽  
Vol 133 ◽  
pp. 51-55 ◽  
Author(s):  
Eva Tůmová ◽  
Darina Chodová ◽  
Jana Vlčková ◽  
Tomáš Němeček ◽  
Linda Uhlířová ◽  
...  
Keyword(s):  
Meat Quality ◽  
Production System ◽  
Myocastor Coypus ◽  
Male And Female ◽  
Carcass Yield ◽  
Intensive Production ◽  
Age Related ◽  
Age Related Changes

Changes with age of mammary glands in male and female soft-furred rat, Millardia meltada, in relation to prolactin and testosterone

1994 ◽  
Vol 28 (1) ◽  
pp. 35-43
Author(s):  
H. Nagasawa ◽  
T. Mori ◽  
S. Sakamoto ◽  
S. Sassa ◽  
Y. Yamamuro ◽  
...  
Keyword(s):  
Enzyme Activities ◽  
De Novo ◽  
Serum Levels ◽  
Mammary Glands ◽  
Ventral Prostate ◽  
Male And Female ◽  
Age Related ◽  
Males And Females ◽  
Salvage Pathways ◽  
Age Related Changes

The soft-furred rat, millardia ( Millardia meltada), is characterized by the development of androgen-dependent mammary tumours only in males. The age-related changes of the activities of thymidylate synthetase (TS) and thymidine kinase (TK), which contribute to DNA synthesis through de novo and salvage pathways, respectively, and structure in the mammary glands were studied in both males and females of this species between 5-28 months of age. While TK activity had no relation to age, TS activity decreased with age in males. In the females, TK activity increased with age, but not TS activity. These enzyme activities were generally higher in females than in males. The mammary glands of both sexes consisted of fine ducts with small end-buds and the glands of males contained mostly black pigments at any age examined. In either males or females, serum levels of prolactin and testosterone related little with age, DNA synthesizing enzyme activities or structure of the mammary glands. Furthermore, elevation by pituitary grafting of circulating prolactin affected neither DNA synthesizing enzyme activities nor structure of mammary glands in both sexes. The histological structures of adrenal, testis, ovary, ventral prostate and uterus of millardia were essentially similar to those of mice or rats.

AGE-RELATED CHANGES IN THE DEGRADATION OF THYROTROPHIN RELEASING HORMONE BY HUMAN AND RAT SERUM

1980 ◽  
Vol 86 (3) ◽  
pp. 397-402 ◽  
Author(s):  
NICKI WHITE ◽  
E. C. GRIFFITHS ◽  
S. L. JEFFCOATE ◽  
R. D. G. MILNER ◽  
M. A. PREECE
Keyword(s):  
Physiological Role ◽  
Serum Samples ◽  
Rat Serum ◽  
Thyrotrophin Releasing Hormone ◽  
Male And Female ◽  
Releasing Hormone ◽  
Clear Cut ◽  
Age Related ◽  
Age Related Changes

Changes in the rate of in-vitro degradation of thyrotrophin releasing hormone (TRH) in serum as related to age have been investigated in the rat and man. In rats, no inactivation was found up to the age of 15 days but thereafter an age-related increase in inactivation was detected with approximately 75% inactivation in 60 min at 40 days and reaching a maximum of 88–93% inactivation in adult male and female animals. The human serum samples studied (both male and female) showed a similar but less clear-cut pattern of inactivation of TRH compared with that found in the rat. A physiological role for these age-related changes in the degradation of TRH remains to be established but it has been concluded that the changes observed in both rat and man may be associated with growth and development, possibly by facilitating feedback control of thyrotrophin secretion through the degradation of TRH.

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