Radiological-Pathological Correlation in Alzheimer’s Disease: Systematic Review of Antemortem Magnetic Resonance Imaging Findings

2017 ◽  
Vol 57 (2) ◽  
pp. 575-601 ◽  
Author(s):  
Caroline Dallaire-Théroux ◽  
Brandy L. Callahan ◽  
Olivier Potvin ◽  
Stéphan Saikali ◽  
Simon Duchesne
Nanomedicine ◽  
2020 ◽  
Vol 15 (7) ◽  
pp. 725-743
Author(s):  
Marina Ulanova ◽  
Anne Poljak ◽  
Wei Wen ◽  
Andre Bongers ◽  
Lucy Gloag ◽  
...  

Nanoparticle (NP)-based magnetic contrast agents have opened the potential for MRI to be used for early diagnosis of Alzheimer’s disease (AD). This article aims to review the current progress of research in this field. A comprehensive literature search was performed based on PubMed, Medline, EMBASE, PsychINFO and Scopus databases using the following terms: ‘Alzheimer’s disease’ AND ‘nanoparticles’ AND ‘Magnetic Resonance Imaging.’ 33 studies were included that described the development and utility of various NPs for AD imaging, including their coating, functionalization, MRI relaxivity, toxicity and bioavailability. NPs show immense promise for neuroimaging, due to superior relaxivity and biocompatibility compared with currently available imaging agents. Consistent reporting is imperative for further progress in this field.


2015 ◽  
Vol 12 (10) ◽  
pp. 1006-1011 ◽  
Author(s):  
Minori Yasue ◽  
Saiko Sugiura ◽  
Yasue Uchida ◽  
Hironao Otake ◽  
Masaaki Teranishi ◽  
...  

2019 ◽  
Author(s):  
Clemens Kruse ◽  
Britney Larson ◽  
Reagan Wilkinson ◽  
Roger Samson ◽  
Taylor Castillo

BACKGROUND Incidence of AD continues to increase, making it the most common cause of dementia and the sixth-leading cause of death in the United States. 2018 numbers are expected to double by 2030. OBJECTIVE We examined the benefits of utilizing technology to identify and detect Alzheimer’s disease in the diagnostic process. METHODS We searched PubMed and CINAHL using key terms and filters to identify 30 articles for review. We analyzed these articles and reported them in accordance with the PRISMA guidelines. RESULTS We identified 11 technologies used in the detection of Alzheimer’s disease: 66% of which used some form of MIR. Functional, structural, and 7T magnetic resonance imaging were all used with structural being the most prevalent. CONCLUSIONS MRI is the best form of current technology being used in the detection of Alzheimer’s disease. MRI is a noninvasive approach that provides highly accurate results in the diagnostic process of Alzheimer’s disease.


2020 ◽  
Vol 16 (S5) ◽  
Author(s):  
Alexa Haeger ◽  
Arthur Coste ◽  
Cécile Lerman‐Rabrait ◽  
Julien Lagarde ◽  
Jörg B. Schulz ◽  
...  

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