Role of Ciliary Neurotrophic Factor in the Proliferation and Differentiation of Neural Stem Cells

2013 ◽  
Vol 37 (3) ◽  
pp. 587-592 ◽  
Author(s):  
Jun Ding ◽  
Zhili He ◽  
Juan Ruan ◽  
Zilong Ma ◽  
Ying Liu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Neurotrophic Factor ◽  
Ciliary Neurotrophic Factor ◽  
Proliferation And Differentiation

scholarly journals Bioelectric State and Cell Cycle Control of Mammalian Neural Stem Cells

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Julieta Aprea ◽  
Federico Calegari
Keyword(s):  
Stem Cells ◽  
Membrane Potential ◽  
Ion Channels ◽  
Neural Stem Cells ◽  
Current Knowledge ◽  
Cell Cycle Control ◽  
Resting Membrane Potential ◽  
Excitable Cells ◽  
Proliferation And Differentiation

The concerted action of ion channels and pumps establishing a resting membrane potential has been most thoroughly studied in the context of excitable cells, most notably neurons, but emerging evidences indicate that they are also involved in controlling proliferation and differentiation of nonexcitable somatic stem cells. The importance of understanding stem cell contribution to tissue formation during embryonic development, adult homeostasis, and regeneration in disease has prompted many groups to study and manipulate the membrane potential of stem cells in a variety of systems. In this paper we aimed at summarizing the current knowledge on the role of ion channels and pumps in the context of mammalian corticogenesis with particular emphasis on their contribution to the switch of neural stem cells from proliferation to differentiation and generation of more committed progenitors and neurons, whose lineage during brain development has been recently elucidated.

The role of interleukin-6 (IL-6) in the proliferation and differentiation of human neural stem cells

2001 ◽  
Vol 29 (1) ◽  
pp. 1-14
Author(s):  
Stefano F. Pagano ◽  
Sabrina Lucchiari ◽  
Alessandra Bez ◽  
Dario Ponti ◽  
Marco Onofrj ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Interleukin 6 ◽  
Human Neural Stem Cells ◽  
Proliferation And Differentiation
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