VueBox® perfusion analysis of contrast-enhanced ultrasound (CEUS) examinations in patients with primary hyperparathyroidism for preoperative detection of parathyroid gland adenoma

2019 ◽  
Vol 70 (4) ◽  
pp. 423-431 ◽  
Author(s):  
Natascha Platz Batista da Silva ◽  
Ernst Michael Jung ◽  
Friedrich Jung ◽  
Hans J. Schlitt ◽  
Matthias Hornung
Keyword(s):  
Primary Hyperparathyroidism ◽  
Parathyroid Gland ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

Utility of contrast-enhanced ultrasound in preoperative evaluation of primary hyperparathyroidism

2018 ◽  
Author(s):  
Paola Parra Ramirez ◽  
Patricia Martin Rojas Marcos ◽  
Antonio Santiago Hernando ◽  
Arturo Lisbona Catalan ◽  
Alejandro Casto Calvo ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Preoperative Evaluation ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

Contrast-enhanced ultrasound (CEUS) and perfusion imaging using VueBox®

2021 ◽  
pp. 1-12
Author(s):  
Isabel Wiesinger ◽  
Friedrich Jung ◽  
Ernst Michael Jung
Keyword(s):  
Quantitative Analysis ◽  
Thyroid Gland ◽  
Parathyroid Gland ◽  
Perfusion Imaging ◽  
Cystic Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

The external perfusion software (VueBox™) for contrast-enhanced ultrasound (CEUS), enables the quantitative analysis of micro-vascularization within non-cystic lesions in terms of characterization and detection. This review summarizes our work about parathyroid gland, thyroid gland, liver, prostate and other tissues as well as original studies in the use of parametric perfusion imaging. Useful perfusion parameters are introduced.

scholarly journals Contrast-Enhanced Ultrasound Qualitative and Quantitative Characteristics of Parathyroid Gland Lesions

Medicina ◽  
2021 ◽  
Vol 58 (1) ◽  
pp. 2
Author(s):  
Sergejs Pavlovics ◽  
Maija Radzina ◽  
Rita Niciporuka ◽  
Madara Ratniece ◽  
Madara Mikelsone ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Contrast Media ◽  
Parathyroid Gland ◽  
Predictive Value ◽  
Contrast Enhanced Ultrasound ◽  
Qualitative And Quantitative ◽  
Contrast Enhanced ◽  
Quantitative Characteristics ◽  
Parathyroid Lesions ◽  
Qualitative And Quantitative Characteristics

Background and Objectives: preoperative differentiation of enlarged parathyroid glands may be challenging in conventional B-mode ultrasound. The aim of our study was to analyse qualitative and quantitative characteristics of parathyroid gland lesions, using multiparametric ultrasound protocol—B-mode, Colour Doppler (CD), and contrast-enhanced ultrasound (CEUS)—and to evaluate correlation with morphology in patients with hyperparathyroidism (HPT). Materials and Methods: consecutive 75 patients with 88 parathyroid lesions and biochemically confirmed HPT prior to parathyroidectomy were enrolled in the prospective study. B-mode ultrasound, CD, and CEUS were performed with the subsequent qualitative and quantitative evaluation of acquired data. We used 1 mL or 2 mL of intravenous ultrasound contrast agent during the CEUS examination. Correlation with post-surgical morphology was evaluated. Results: seventy parathyroid adenomas were hypoechoic and well contoured with increased central echogenicity (44.3%), peripheral-central vascularization (47%), and polar feeding vessel (100%). Twelve hyperplasias presented with similar ultrasound appearance and were smaller in volume (p = 0.036). Hyperplasias had a tendency for homogenous, marked intense enhancement vs. peripherally enhanced adenomas with central wash-out in CEUS after quantitative analysis. No significant difference was observed in contrasting dynamics, regardless of contrast media volume use (1 mL vs. 2 mL). We achieved 90.9% sensitivity and 72.7% specificity, 93% positive predictive value (PPV), 87.3% negative predictive value (NPV), and 87.3% accuracy in the differentiation of parathyroid lesions prior to post-processing. In a quantitative lesion analysis, our sensitivity increased up to 98%, specificity 80%, PPV 98%, and NPV 80% with an accuracy of 96.4%. Conclusions: CEUS of parathyroid lesions shows potential in the differentiation of adenoma from hyperplasia, regardless of the amount of contrast media injected. The quantitative analysis improved the sensitivity and specificity of differentiation between parathyroid lesions. Hyperplasia was characterized by homogeneous enhancement, fast uptake, and homogeneous wash-out appearance; adenoma—by peripheral uptake, central wash-out, and reduced hemodynamics. The use of CEUS quantification methods are advised to improve the ultrasound diagnostic role in suspected parathyroid lesions.

Potential Utility of Contrast‐Enhanced Ultrasound in the Preoperative Evaluation of Primary Hyperparathyroidism

2019 ◽  
Vol 38 (10) ◽  
pp. 2565-2571 ◽  
Author(s):  
Paola Parra Ramírez ◽  
Antonio Santiago Hernando ◽  
Beatriz Barquiel Alcalá ◽  
Patricia Martín Rojas‐Marcos ◽  
Arturo Lisbona Catalán ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Preoperative Evaluation ◽  
Potential Utility ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

1687: Directed Prostate Biopsies Utilizing Microflow Imaging During Microbubble Contrast-Enhanced Ultrasound

2007 ◽  
Vol 177 (4S) ◽  
pp. 560-560
Author(s):  
Robert A. Linden ◽  
Paul R. Gittens ◽  
Flemming Forsberg ◽  
Edouard J. Trabulsi ◽  
Leonard G. Gomella ◽  
...  
Keyword(s):  
Contrast Enhanced Ultrasound ◽  
Prostate Biopsies ◽  
Contrast Enhanced

1929: Contrast Enhanced Ultrasound Monitoring of Radiofrequency Ablation

2004 ◽  
Vol 171 (4S) ◽  
pp. 509-510
Author(s):  
D Brooke Johnson ◽  
David A. Duchene ◽  
Grant D. Taylor ◽  
Jeffrey A. Cadeddu
Keyword(s):  
Radiofrequency Ablation ◽  
Contrast Enhanced Ultrasound ◽  
Ultrasound Monitoring ◽  
Contrast Enhanced
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