Diagnostic performance of thyroid imaging reporting and data system (TI-RADS) alone and in combination with contrast-enhanced ultrasonography for the characterization of thyroid nodules

2019 ◽  
Vol 72 (1) ◽  
pp. 95-106 ◽  
Author(s):  
Huaqun Zhao ◽  
Xueling Liu ◽  
Bei Lei ◽  
Ping Cheng ◽  
Jian Li ◽  
...  
2020 ◽  
Vol 2020 ◽  
pp. 1-11 ◽  
Author(s):  
Shufang Pei ◽  
Bin Zhang ◽  
Shuzhen Cong ◽  
Juanjuan Liu ◽  
Suqing Wu ◽  
...  

Background. To explore the correlation between the ultrasound elasticity score (ES) of real-time tissue elastography (RTE) and the malignant risk stratification of the Thyroid Imaging Reporting and Data System (TI-RADS) and to evaluate the added value of RTE to TI-RADS in differentiating malignant nodules from benign ones. Methods. A total of 1,498 patients (885 women and 613 men; mean age of 43.5 ± 12.4 years) with 1,525 confirmed thyroid nodules (D = maximum diameter, D ≤ 2.5 cm) confirmed by fine-needle aspiration (FNA) and/or surgery were included. The nodules were divided into four groups based on their sizes (D ≤ 0.5 cm, 0.5 < D ≤ 1.0 cm, 1.0 < D ≤ 2.0 cm, and 2.0 < D ≤ 2.5 cm). We assigned an ES of RTE and malignant risk stratification of the TI-RADS category to each nodule. The correlation between the ES of RTE and the malignant risk stratification of TI-RADS category was analyzed by the Spearman’s rank correlation. The diagnostic performances of RTE, TI-RADS, and their combination were compared by the receiver operator characteristic (ROC) analysis. Results. The ES of RTE and the malignant risk stratification of TI-RADS showed a strong correlation in the size intervals of 0.5 < D ≤ 1.0 cm, 1.0 < D ≤ 2.0 cm, and 2.0 < D ≤ 2.5 cm (r = 0.768, 0.711, and 0.743, respectively). The diagnostic performance of their combination for each size interval was always better than RTE or TI-RADS alone (for all, P<0.001). Conclusions. Overall, The ES of RTE was strongly correlated with the malignant risk stratification of TI-RADS. The diagnostic performance of the combination of RTE and TI-RADS outperformed RTE or TI-RADS alone. Therefore, RTE may be an adjunctive tool to the current TI-RADS system for differentiating malignant from benign thyroid nodules.


Head & Neck ◽  
2012 ◽  
Vol 35 (4) ◽  
pp. 541-547 ◽  
Author(s):  
Shih-Ping Cheng ◽  
Jie-Jen Lee ◽  
Jiun-Lu Lin ◽  
Shih-Ming Chuang ◽  
Ming-Nan Chien ◽  
...  

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