Ultrasound elastography in diagnosis and follow-up for patients with chronic recurrent parotitis

2017 ◽  
Vol 67 (3-4) ◽  
pp. 389-397 ◽  
Author(s):  
Pamela Zengel ◽  
Christoph Andreas Reichel ◽  
Teresa Vincek ◽  
Dirk André Clevert
Keyword(s):  
Ultrasound Elastography ◽  
Chronic Recurrent Parotitis

Prospective Evaluation of Semiquantitative Strain Ratio and Quantitative 2D Ultrasound Shear Wave Elastography (SWE) in Association with TIRADS Classification for Thyroid Nodule Characterization

2019 ◽  
Vol 40 (04) ◽  
pp. 495-503 ◽  
Author(s):  
Vito Cantisani ◽  
Emanuele David ◽  
Hektor Grazhdani ◽  
Antonello Rubini ◽  
Maija Radzina ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Shear Wave ◽  
Diagnostic Performance ◽  
Thyroid Nodules ◽  
Shear Wave Elastography ◽  
Strain Ratio ◽  
Ultrasound Elastography ◽  
Prospective Evaluation ◽  
2D Ultrasound

Abstract Purpose To evaluate the diagnostic performance of strain ratio elastography (SRE) and shear wave elastography (SWE) alone and in combination with Thyroid Imaging Reporting and Data System (TIRADS) classification parameters to improve differentiation between benign and malignant thyroid nodules. Materials and Methods In this prospective study benign (n = 191) and malignant (n = 52) thyroid nodules were examined with high-resolution ultrasound (US) features using the TIRADS lexicon and SRE semiquantitative and SWE quantitative findings using histology or cytology as the gold standard with a 12-month follow-up. Sensitivity (Se), specificity (Sp) and the area under the ROC curve (AUROC) were used to evaluate the diagnostic performance of each feature and combinations of the methods. Results TIRADS score showed a sensitivity of 59.6 %, a specificity of 83.8 % with an AUROC of 0.717, a PPV of 50.0 % and an NPV of 88.4 %. SRE yielded the highest performance with a sensitivity of 82.7 %, a specificity of 92.7 % with AUROC of 0.877, a PPV 75.4 % and an NPV of 95.2 %. SWE (kPa) had a sensitivity and specificity of 67.3 % and 82.7 %, respectively, with an AUROC of 0.750, a PPV of 51.5 % and an NPV of 90.3 %. Differences were significant for SRE only but not for SWE. Conclusion Ultrasound elastography may improve thyroid nodule discrimination. In particular, SRE has a better performance than TIRADS classification, while their combination improves sensitivity.

SONOGRAPHIC FOLLOW-UP OF PATIENTS WITH DIFFERENTIATED THYROID CARCINOMA: A COMPARISON OF THE ULTRASOUND ELASTOGRAPHY, POWER DOPPLER ULTRASOUND, AND B-MODE ULTRASOUND FEATURES IN DETECTING MALIGNANT LYMPH NODES

2019 ◽  
Vol 25 (10) ◽  
pp. 1049-1055
Author(s):  
Berna İmge Aydoğan ◽  
Ugur Ünlütürk ◽  
Funda Seher Özalp Ateş ◽  
Murat Faik Erdoğan
Keyword(s):  
Thyroid Cancer ◽  
Lymph Node ◽  
Positive Predictive Value ◽  
Lymph Nodes ◽  
Predictive Value ◽  
Differentiated Thyroid Cancer ◽  
Power Doppler ◽  
Ultrasound Elastography ◽  
Malignant Lymph Nodes

Objective: The aim of this study was to assess and compare the diagnostic power of B-mode ultrasonography (US), power Doppler US (PD), and ultrasound elastography (USE) in detecting malignant lymph nodes (LNs) during follow-up of patients who were operated on for differentiated thyroid cancer (DTC). Methods: In this prospective study, a total of 103 cervical LNs having suspicious malignant features from 72 patients with DTC were examined using US, PD, and USE. USE scores were classified from 1 to 3 according to the presence of elasticity (1, soft; 2, intermediate; 3, hard). The strain ratios (SRs) of all LNs were calculated according to adjacent muscle tissue. Results: The most-sensitive ultrasonographic features were hilum loss and hypoechogenicity, with 94.4% and 80.6% sensitivity and 93.5% and 84.4% negative predictive value, respectively. The most-specific feature was the presence of cystic component, with 98.5% specificity and 85.7% positive predictive value. Presence of diffuse/chaotic or irregular vascularity in PD had 47.2% sensitivity and 83.6% specificity in predicting metastasis. In USE, the sensitivity and specificity of score 3 were 56.7% and 74.2%, respectively. The median SR of metastatic LNs was higher than that of benign LNs (median SR [min–max], 3.0 [0.16 and 29] vs. 1.89 [0.26 and 37.9]), but the difference was not significant ( P = .07). Multivariate logistic regression analyses revealed 4.9-, 6.6-, and 10-fold increases in metastasis risk for short/long axis ratio ≥0.5, nodal vascularity, and score 3 USE, respectively ( P<.05). Conclusion: While USE had higher sensitivity, PD had higher specificity in detecting malignant LNs, but none of these techniques was as sensitive and specific as gray-scale US features. Abbreviations: CI = confidence interval; DTC = differentiated thyroid cancer; LN = lymph node; LN-Tg = lymph node–thyroglobulin; NPV = negative predictive value; PD = power Doppler; PPV = positive predictive value; ROI = region of interest; SR = strain ratio; US = ultrasonography; USE = ultrasound elastography

Value of the Ultrasound Elastography in the Diagnosis of Thyroid Nodules

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
T I A Ouf ◽  
H H Hanna ◽  
A M B Ghaly
Keyword(s):  
Predictive Value ◽  
Thyroid Nodules ◽  
Nodular Goiter ◽  
Ultrasound Elastography ◽  
University Hospital ◽  
Common Occurrence ◽  
Ethical Committee Approval ◽  
High Negative Predictive Value ◽  
High Positive Predictive Value

Abstract Background Thyroid disease is of common occurrence, especially in iodine deficient areas. Thyroid nodules have been reported in as many as 50% of the population, at autopsy. They may be discovered in up to 41% of the patients at ultrasonography (US). Aim of the Work The aim of this study is to evaluate the value of Ultrasound- Elastography in the Diagnosis of thyroid nodules for reducing the number of unnecessary Thyroidectomises which add burden to the patient and community, consequently the complications of this surgery will be reduced. Patients and Methods This prospective cohort study was conducted at El Demerdash, Ain Shams University Hospital on Fifty (50) patients with the diagnosis of multi-nodular goiter, who were treated by total thyroidectomy between November 2016 and November 2018 with minimum follow up of one month postoperatively. An informed consent was taken from all patients who accepted to participate in our study after ethical committee approval. Results Elastography has 100% sensitivity and 95.5% specificity as it suspected malignancy (positive suspecting findings) in 8 patients; six of them were proved to be malignant and two of them were benign by histopathology accounting for high positive predictive value (75%) and it suspected benignity (negative suspecting findings) in 42 patients; all of them were perfectly correlated with the histopathology accounting for high negative predictive value (100%). These results showed nearly the same values of the Elastography in the previous studies had been done regarding this concern. Conclusion Conclusively, In the future, FNAC perhaps will not be used for the diagnosis of malignancy in patients presented with multi-nodular goitres who were diagnosed as suspicious of malignancy by Sono-elastography.

Noninvasive vascular ultrasound elastography applied to the characterization of experimental aneurysms and follow-up after endovascular repair

2008 ◽  
Vol 53 (22) ◽  
pp. 6475-6490 ◽  
Author(s):  
Jérémie Fromageau ◽  
Sophie Lerouge ◽  
Roch Listz Maurice ◽  
Gilles Soulez ◽  
Guy Cloutier
Keyword(s):  
Endovascular Repair ◽  
Ultrasound Elastography ◽  
Vascular Ultrasound

scholarly journals Staging liver fibrosis after severe yellow fever with ultrasound elastography in Brazil: A six-month follow-up study

2021 ◽  
Vol 15 (7) ◽  
pp. e0009594
Author(s):  
Yuri Costa Sarno Neves ◽  
Victor Augusto Camarinha de Castro-Lima ◽  
Davi Jorge Fontoura Solla ◽  
Vivian Simone de Medeiros Ogata ◽  
Fernando Linhares Pereira ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Yellow Fever ◽  
Previous History ◽  
Liver Stiffness ◽  
Shear Wave Elastography ◽  
Liver Parenchyma ◽  
Ultrasound Elastography ◽  
Hemorrhagic Disease ◽  
Saps 3

Background Yellow fever (YF) is a hemorrhagic disease caused by an arbovirus endemic in South America, with recent outbreaks in the last years. Severe cases exhibit fulminant hepatitis, but there are no studies regarding its late-term effects on liver parenchyma. Thus, the aim of this study was to determine the frequency and grade of liver fibrosis in patients who recovered from severe YF and to point out potential predictors of this outcome. Methodology/Principal findings We followed-up 18 patients who survived severe YF during a recent outbreak (January-April 2018) in Brazil using ultrasound (US) with shear-wave elastography (SWE) at 6 months after symptoms onset. No patient had previous history of liver disease. Median liver stiffness (LS) was 5.3 (4.6–6.4) kPa. 2 (11.1%) patients were classified as Metavir F2, 1 (8.3%) as F3 and 1 (8.3%) as F4; these two last patients had features of cardiogenic liver congestion on Doppler analysis. Age and cardiac failure were associated with increased LS (p = 0.036 and p = 0.024, respectively). SAPS-3 at ICU admission showed a tendency of association with significant fibrosis (≥ F2; p = 0.053). 7 patients used sofosbuvir in a research protocol, of which none showed liver fibrosis (p = 0.119). Conclusions/Significance We found a low frequency of liver fibrosis in severe YF survivors. US with SWE may have a role in the follow up of patients of age and / or with comorbidities after hospital discharge in severe YF, a rare but reemergent disease.

Ambroxol chaperone therapy for Gaucher disease type I-associated liver cirrhosis and portal hypertension: a case report

2021 ◽  
Vol 21 ◽  
Author(s):  
Peng Zhang ◽  
Mei-Fang Zheng ◽  
Shi-Yuan Cui ◽  
Wei Zhang ◽  
Run-Ping Gao
Keyword(s):  
Liver Cirrhosis ◽  
Case Report ◽  
Portal Hypertension ◽  
Gaucher Disease ◽  
Liver Stiffness ◽  
Ultrasound Elastography ◽  
High Dose ◽  
Type I ◽  
Long Term Treatment

Background: Gaucher disease (GD) is a rare autosomal recessive inherited disease caused by the deficiency of glucocerebrosidase and characterized by a broad spectrum of clinical manifestations, including hepatosplenomegaly, bone infiltration, and cytopenia. Moreover, it is even involved in the central nervous system. GD is classified into three phenotypes on the ground of neurologic involvement: type 1 (GD1), the commonly adult-onset, non-neuropathic variant; type 2 (GD2), the acute neuropathic form; and type 3 (GD3), the severe chronic neuro-visceral form. Recently, several studies have shown a promising outcome of ambroxol chaperone therapy for the treatment of GD, but its therapeutic role in GD1-associated liver cirrhosis and portal hypertension was not verified. Case presentation: A 36-year-old male patient was admitted for esophageal varices lasting for one year with a 34-year history of liver and spleen enlargement. The patient was diagnosed with GD1 with cirrhosis and portal hypertension based on the identification of Gaucher cells and advanced fibrosis in the liver biopsy tissue and two known pathogenic mutations on the glucocerebrosidase (GBA) gene. The patient received 660 mg/d of ambroxol for up to two years. At his six-month follow-up, the patient exhibited a remarkable increase in GBA activity (+35.5%) and decrease in liver stiffness (-19.5%) and portal vein diameter (-41.2%) as examined by ultrasound elastography and computer tomography, respectively. At two-year follow-up, the liver stiffness was further reduced (-55.5%) in comparison with untreated patients. Conclusion: This case report suggests that long-term treatment with high dose ambroxol may play a role in the reduction of hepatic fibrosis in GD1.

6F-4 Ultrasound Elastography for the Non-invasive Healing Follow-Up of Abdominal Aneurysms

2006 ◽  
Author(s):  
J. Fromageau ◽  
S. Lerouge ◽  
R. L. Maurice ◽  
G. Soulez ◽  
G. Cloutier
Keyword(s):  
Ultrasound Elastography ◽  
Non Invasive

scholarly journals Ultrasound elastography techniques for diagnosis and follow-up of hepatic veno-occlusive disease

2019 ◽  
Vol 54 (7) ◽  
pp. 1145-1147 ◽  
Author(s):  
Lorenzo Lazzari ◽  
Paolo Marra ◽  
Raffaella Greco ◽  
Fabio Giglio ◽  
Daniela Clerici ◽  
...  
Keyword(s):  
Occlusive Disease ◽  
Ultrasound Elastography
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