Discovery and validation of ovarian cancer biomarkers utilizing high density antibody microarrays

2011 ◽  
Vol 8 (4-5) ◽  
pp. 293-307 ◽  
Author(s):  
Arturo B. Ramirez ◽  
Paul D. Lampe
Keyword(s):  
Ovarian Cancer ◽  
Cancer Biomarkers ◽  
High Density ◽  
Antibody Microarrays

scholarly journals Discovery of sialyl Lewis A and Lewis X modified protein cancer biomarkers using high density antibody arrays

2014 ◽  
Vol 96 ◽  
pp. 291-299 ◽  
Author(s):  
Jung-hyun Rho ◽  
Judson R. Mead ◽  
W. Shea Wright ◽  
Dean E. Brenner ◽  
James W. Stave ◽  
...  
Keyword(s):  
Cancer Biomarkers ◽  
High Density ◽  
Lewis X ◽  
Sialyl Lewis ◽  
Sialyl Lewis A ◽  
Antibody Arrays ◽  
Lewis A

The utility of additional ovarian cancer biomarkers to the dual marker combination of HE4 and CA-125 for the detection of cancer

2018 ◽  
Vol 149 ◽  
pp. 67-68 ◽  
Author(s):  
A.M. Blackman ◽  
M.C. Miller ◽  
E. Eklund ◽  
R.M. Strongin ◽  
G. Messerlian ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Biomarkers ◽  
Ca 125 ◽  
Marker Combination

scholarly journals Changes in Tumorigenesis- and Angiogenesis-related Gene Transcript Abundance Profiles in Ovarian Cancer Detected by Tailored High Density cDNA Arrays

2000 ◽  
Vol 6 (9) ◽  
pp. 750-765 ◽  
Author(s):  
Ann-Marie Martoglio ◽  
Brian D. M. Tom ◽  
Michael Starkey ◽  
Anthony N. Corps ◽  
D. Stephen Charnock-Jones ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Transcript Abundance ◽  
High Density ◽  
Gene Transcript ◽  
Related Gene ◽  
Cdna Arrays ◽  
Angiogenesis Related Gene

Multi-omics in high-grade serous ovarian cancer: Biomarkers from genome to the immunome

2018 ◽  
Vol 80 (2) ◽  
pp. e12975 ◽  
Author(s):  
Cole Clifford ◽  
Natasha Vitkin ◽  
Sarah Nersesian ◽  
Gillian Reid-Schachter ◽  
Julie-Ann Francis ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Biomarkers ◽  
High Grade ◽  
Serous Ovarian Cancer

Abstract 1570: Early Detection Research Network (EDRN) validation of circulating ovarian cancer biomarkers

2015 ◽  
Author(s):  
Steven J. Skates ◽  
Karen S. Anderson ◽  
Tao Liu ◽  
Vathany Kulasingam ◽  
Dustin Rabideau ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Early Detection ◽  
Cancer Biomarkers ◽  
Research Network

Abstract B13: Discovery of novel subtype-specific ovarian cancer biomarkers via integrated tissue proteomics.

2016 ◽  
Author(s):  
Felix Leung ◽  
Marcus Q. Bernardini ◽  
Blaise Clarke ◽  
Marjan Rouzbahman ◽  
Eleftherios P. Diamandis ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Biomarkers ◽  
Tissue Proteomics

scholarly journals Ovarian Cancer Biomarkers: Current Options and Future Promise

2008 ◽  
Vol 6 (8) ◽  
pp. 795-802 ◽  
Author(s):  
Christine M. Coticchia ◽  
Jiang Yang ◽  
Marsha A. Moses
Keyword(s):  
Ovarian Cancer ◽  
Disease Progression ◽  
Cancer Detection ◽  
Therapeutic Efficacy ◽  
Cancer Biomarkers ◽  
Cancer Diagnostics ◽  
Early Disease ◽  
Molecular Approaches ◽  
Ovarian Cancer Diagnostics ◽  
Potential Biomarkers

As more effective, less toxic cancer drugs reach patients, the need for accurate and reliable cancer diagnostics and prognostics has become widely appreciated. Nowhere is this need more dire than in ovarian cancer; here most women are diagnosed late in disease progression. The ability to sensitively and specifically predict the presence of early disease and its status, stage, and associated therapeutic efficacy has the potential to revolutionize ovarian cancer detection and treatment. This article reviews current ovarian cancer diagnostics and prognostics and potential biomarkers that are being studied and validated. Some of the most recent molecular approaches being used to identify genes and proteins are presented, which may represent the next generation of ovarian cancer diagnostics and prognostics.

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