Downregulated circular RNA itchy E3 ubiquitin protein ligase correlates with advanced pathologic T stage, high lymph node metastasis risk and poor survivals in prostate cancer patients

2019 ◽  
Vol 26 (1) ◽  
pp. 41-50 ◽  
Author(s):  
Enying Huang ◽  
Xiaogang Chen ◽  
Yuan Yuan
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cancer Patients ◽  
Circular Rna ◽  
Ubiquitin Protein Ligase ◽  
Node Metastasis ◽  
T Stage ◽  
High Lymph Node

298 LONG-TERM OUTCOMES FOR PROSTATE CANCER PATIENTS WITH LYMPH NODE METASTASIS AFTER RADICAL PROSTATECTOMY

2011 ◽  
Vol 185 (4S) ◽  
Author(s):  
Clarisse Mazzola ◽  
Youness Ahallal ◽  
Tarek Ghoneim ◽  
Daniel Sjoberg ◽  
Bertrand Guillonneau ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Radical Prostatectomy ◽  
Lymph Node Metastasis ◽  
Cancer Patients ◽  
Long Term Outcomes ◽  
Node Metastasis

scholarly journals The immune checkpoint regulator PD-L1 expression are associated with clinical progression in prostate cancer

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Juan He ◽  
Min Yi ◽  
Lingfeng Tan ◽  
Jianghua Huang ◽  
Lin Huang
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Gleason Score ◽  
Tumour Cells ◽  
Node Metastasis ◽  
T Stage ◽  
Positive Expression ◽  
Programmed Death ◽  
Programmed Death 1

Abstract Background The programmed death 1 (PD-1)/programmed death-ligand 1 (PD-L1) have shown positive efficacy in several solid cancers due to their targeted antitumour effects. However, the frequency and clinical implication value in prostate cancer still remain unclear. Methods The PD-1/PD-L1 expression was detected by immunohistochemical (IHC) analysis in 96 retrospectively collected cases of prostatic cancer and 44 controls of benign prostatic hyperplasia (BPH). Its correlation with clinicopathological features including age, PSA level, Gleason score, lymph node metastasis, clinical T stage and risk factor grade in prostate cancer was also assessed. Results The PD-L1-positive expression was significantly higher in cancer cases compared with benign tissues, whereas no difference in PD-1 positive expression was found. Moreover, the PD-L1 expression in tumour cells or lymphocytes was associated with Gleason score, but not related to age, preoperative PSA level, clinical T-stage, lymph node metastasis and grade of risk factors. In addition, no association between the positive expression of PD-1 and PD-L1 in tumour cells and lymphocytes was found. Conclusions The expression of PD-L1 not PD-1 is highly prevalent in prostate cancer. PD-L1 is closely related to Gleason score and may be a co-factor associated with the progression of prostate cancer.

CELL PROLIFERATION IN PROSTATE CANCER PATIENTS WITH LYMPH NODE METASTASIS

1999 ◽  
pp. 175 ◽  
Author(s):  
Liang Cheng ◽  
Thomas J. Sebo ◽  
Bradley C. Leibovich ◽  
Dharamdas M. Ramnani ◽  
Beth G. Scherer ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Proliferation ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cancer Patients ◽  
Node Metastasis

The Value of 99mTc-PSMA SPECT/CT-Guided Surgery for Identifying and Locating Lymph Node Metastasis in Prostate Cancer Patients

2018 ◽  
Vol 26 (2) ◽  
pp. 653-659 ◽  
Author(s):  
Heng-chuan Su ◽  
Yao Zhu ◽  
Si-long Hu ◽  
Chang Liu ◽  
Guo-wen Lin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cancer Patients ◽  
Ct Guided ◽  
Guided Surgery ◽  
Node Metastasis
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