Mouse Coronary Angiography In Vivo Using Synchrotron Radiation

2014 ◽  
Vol 24 (1) ◽  
pp. 1341-1349
Author(s):  
Lijun Xu ◽  
Andi Zhang ◽  
Guohao Du ◽  
Honglan Xie ◽  
Ying Chen
Keyword(s):  
Synchrotron Radiation ◽  
Coronary Angiography

scholarly journals Influence of ionic and non-ionic radiographic contrast media on leukocyte adhesion molecules

2003 ◽  
Vol 12 (5) ◽  
pp. 269-275 ◽  
Author(s):  
Guy L. J. Vermeiren ◽  
Roel Willems ◽  
Marc J. Claeys ◽  
Chris Vrints ◽  
Herman Slegers ◽  
...  
Keyword(s):  
Coronary Angiography ◽  
Contrast Media ◽  
Adhesion Molecules ◽  
Leukocyte Adhesion ◽  
Serum Samples ◽  
Cd11b Expression ◽  
Radiographic Contrast ◽  
Radiographic Contrast Media

Background:Many papers have focused on the importance of granulocytes in the process of reperfusion and ischemia. Most of the clinical studies measured several parameters of this process during and after coronary angiography, without taking into account the effect of the radiographic contrast media (RCM) used during this procedure.Materials and methods:We performed a randomized patient study(n=37)to evaluate the effect of ionic and non-ionic RCM on granulocyte adhesion during coronary angiography. We also evaluated the influence of the ionicity and osmolarity of the different substances on granulocyte adhesion molecules inin vitroexperiments.Results:The osmolarity of patient serum samples increased from 302±1 to 309±1 mOsm/kg(P<0.05)after infusion of RCM. The CD11b expression in the samples of the non-ionic RCM treated group increased from 221±21 MFI to 377±30 MFI(P<0.05)measured as the absolute mean fluorescence intensity (MFI), yet did not alter significantly in the ionic RCM group. In contrast, thein vitroexperiments showed a reduction of the CD11b expression from 360±70 MFI to 149±30 MFI(P<0.05)in the ionic RCM group.Conclusions:The upregulation of adhesion molecules was significantly reducedin vivowith ionic RCM, while ionic substances caused opposite effectsin vitro. This effect should be taken into account when performing leukocyte functional analysis of samples taken during angiography.

A dual line multicell ionization chamber for transvenous coronary angiography with synchrotron radiation

1995 ◽  
Vol 66 (2) ◽  
pp. 2327-2329 ◽  
Author(s):  
R. H. Menk ◽  
W.‐R. Dix ◽  
W. Graeff ◽  
G. Illing ◽  
B. Reime ◽  
...  
Keyword(s):  
Synchrotron Radiation ◽  
Coronary Angiography ◽  
Ionization Chamber

Renal contrast microangiography with synchrotron radiation: a novel method for visualizing structures within nephrons in vivo

2016 ◽  
Vol 58 (4) ◽  
pp. 505-510 ◽  
Author(s):  
Ken Miya ◽  
Shonosuke Matsushita ◽  
Kazuyuki Hyodo ◽  
Chiho Tokunaga ◽  
Hiroaki Sakamoto ◽  
...  
Keyword(s):  
Synchrotron Radiation ◽  
Ccd Camera ◽  
Average Diameter ◽  
Blocking Agent ◽  
Neuromuscular Blocking ◽  
Proximal Tubules ◽  
X Rays ◽  
Renal Microcirculation ◽  
Male Wistar Rats

Background No non-invasive method of observing renal microcirculation in vivo has been established as yet. Although angiography is considered to be ideally suited for the purpose, conventional X-rays cannot be used to image structures smaller than 100 µm. Purpose To develop a method for visualizing the renal arterioles, glomeruli, and proximal tubules of rats in vivo making use of synchrotron radiation. Material and Methods Male Wistar rats were anesthetized, and a catheter was inserted via laparotomy into the abdominal aorta with its tip placed above the renal arteries. The rats were paralyzed with a neuromuscular blocking agent and mechanically ventilated. An inorganic iodine contrast medium was injected via the catheter. The SR derived X-rays transmitted through the subjects were recorded with a CCD camera. Two-dimensional images with a pixel size of 9 µm were obtained. The exposure time was fixed at 50 ms, with a maximum acquisition rate of three images/s. Results Renal arterioles as small as 18 µm in diameter, glomeruli with an average diameter of 173 ± 21 µm, as well as proximal tubules, were clearly visualized. In addition, glomerular density at the peripheral renal cortex was measurable. Conclusion Rat renal microcirculation could be successfully observed in real-time, without exteriorization of the kidney in this study.

Comparison of intravenous coronary angiography using synchrotron radiation with selective coronary angiography

2003 ◽  
Vol 10 (3) ◽  
pp. 219-227 ◽  
Author(s):  
W.-R. Dix ◽  
W. Kupper ◽  
T. Dill ◽  
C. W. Hamm ◽  
H. Job ◽  
...  
Keyword(s):  
Synchrotron Radiation ◽  
Coronary Angiography ◽  
Selective Coronary Angiography

First human transvenous coronary angiography at the European Synchrotron Radiation Facility

2000 ◽  
Vol 45 (9) ◽  
pp. L39-L43 ◽  
Author(s):  
H Elleaume ◽  
S Fiedler ◽  
F Estève ◽  
B Bertrand ◽  
A M Charvet ◽  
...  
Keyword(s):  
Synchrotron Radiation ◽  
Coronary Angiography ◽  
European Synchrotron Radiation Facility

In vivo real-time microangiography of the liver in mice using synchrotron radiation

2004 ◽  
Vol 40 (3) ◽  
pp. 405-408 ◽  
Author(s):  
Shogo Kobayashi ◽  
Masatoshi Hori ◽  
Keizo Dono ◽  
Hiroaki Nagano ◽  
Koji Umeshita ◽  
...  
Keyword(s):  
Synchrotron Radiation ◽  
Real Time
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