PolyNaSS bioactivation of LARS artificial ligament promotes human ligament fibroblast colonisation in vitro

2013 ◽  
Vol 23 (4) ◽  
pp. 289-297
Author(s):  
Soucounda Lessim ◽  
Véronique Migonney ◽  
Patricia Thoreux ◽  
Didier Lutomski ◽  
Sylvie Changotade
Keyword(s):  
Artificial Ligament ◽  
Lars Artificial Ligament

In Vitro and In Vivo Degradation, Mechanical Properties, and Histocompatibility of Weft-Knitted Silk Mesh-Like Grafts

2022 ◽  
Vol 12 (2) ◽  
pp. 411-416
Author(s):  
Liang Tang ◽  
Si-Yu Zhao ◽  
Ya-Dong Yang ◽  
Geng Yang ◽  
Wen-Yuan Zhang ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Degradation Rate ◽  
Maximum Load ◽  
Artificial Ligament ◽  
In Vivo Degradation

To investigate the degradation, mechanical properties, and histocompatibility of weft-knitted silk mesh-like grafts, we carried out the In Vitro and In Vivo silk grafts degradation assay. The In Vitro degradation experiment was performed by immersing the silk grafts in simulated body fluid for 1 year, and the results showed that the degradation rate of the silk mesh-like grafts was very slow, and there were few changes in the mechanical properties and quality of the silk mesh-like graft. In Vivo degradation assay was taken by implantation of the silk mesh-like grafts into the subcutaneous muscles of rabbits. At 3, 6, and 12 months postoperation, the rate of mass loss was 19.36%, 31.84%, and 58.77%, respectively, and the maximum load was 63.85%, 34.63%, and 10.76%, respectively of that prior to degradation. The results showed that the degradation rate of the silk graft and the loss of mechanical properties In Vivo were faster than the results obtained in the In Vitro experiments. In addition, there were no significant differences in secretion of serum IL-6 and TNF-α between the experimental and normal rabbits (P >0.05), suggesting no obvious inflammatory reaction. The findings suggest that the weft-knitted silk mesh-like grafts have good mechanical properties, histocompatibility, and In Vivo degradation rate, and therefore represent a candidate material for artificial ligament

The biochemical and histological effects of artificial ligament wear particles: In vitro and in vivo studies

1988 ◽  
Vol 16 (6) ◽  
pp. 558-570 ◽  
Author(s):  
Eric J. Olson ◽  
James D. Kang ◽  
Freddie H. Fu ◽  
Helga I. Georgescu ◽  
Gregg C. Mason ◽  
...  
Keyword(s):  
In Vivo Studies ◽  
Wear Particles ◽  
Artificial Ligament

Outcomes of Arthroscopic Double-bundle PCL Reconstruction Using the LARS Artificial Ligament

Orthopedics ◽  
2012 ◽  
Vol 35 (6) ◽  
pp. e800-e806 ◽  
Author(s):  
Chao-Ping Chen ◽  
Yu-Min Lin ◽  
Yung-Cheng Chiu ◽  
Hong-Wen Wu ◽  
Cheng-Hung Lee ◽  
...  
Keyword(s):  
Double Bundle ◽  
Pcl Reconstruction ◽  
Artificial Ligament ◽  
Lars Artificial Ligament
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