The viscous characterization of hydroxyethyl starch (HES) plasma volume expanders in a non-Newtonian blood analog

Biorheology ◽  
2013 ◽  
Vol 50 (3-4) ◽  
pp. 177-190
Author(s):  
Andrew M. Walker ◽  
Yao Xiao ◽  
Clifton R. Johnston ◽  
David E. Rival
Keyword(s):  
Hydroxyethyl Starch ◽  
Plasma Volume

Characterization of Hydroxyethyl Starch by Polymer Analysis for Use as a Plasma Volume Expander

1993 ◽  
Vol 45 (12) ◽  
pp. 445-450 ◽  
Author(s):  
Werner-Michael Kulicke ◽  
Dierk Roessner ◽  
Wiebke Kull
Keyword(s):  
Hydroxyethyl Starch ◽  
Plasma Volume ◽  
Polymer Analysis ◽  
Plasma Volume Expander ◽  
Volume Expander

Impact of high molecular hydroxyethyl starch solutions on plasma volume and haemodynamics in porcine faecal peritonitis

2006 ◽  
Vol 23 (Supplement 37) ◽  
pp. 189
Author(s):  
T. P. Simon ◽  
T. Schuerholz ◽  
P. Petzel ◽  
S. P. Haugvik ◽  
C. Forberger ◽  
...  
Keyword(s):  
Hydroxyethyl Starch ◽  
Plasma Volume ◽  
Faecal Peritonitis

RESUSCITATION FROM SEPTIC SHOCK WITH CAPILLARY LEAKAGE: HYDROXYETHYL STARCH (130 KD), BUT NOT RINGER’S SOLUTION MAINTAINS PLASMA VOLUME AND SYSTEMIC OXYGENATION

Shock ◽  
2004 ◽  
Vol 21 (4) ◽  
pp. 336-341 ◽  
Author(s):  
Gernot Marx ◽  
Samantha Pedder ◽  
Linda Smith ◽  
Seshapillai Swaraj ◽  
Steve Grime ◽  
...  
Keyword(s):  
Septic Shock ◽  
Hydroxyethyl Starch ◽  
Plasma Volume ◽  
Capillary Leakage ◽  
Ringer’S Solution

Plasma volume expansion by medium molecular weight hydroxyethyl starch in neonates: A pilot study*

2003 ◽  
Vol 4 (3) ◽  
pp. 305-307 ◽  
Author(s):  
Jean-Michel Liet ◽  
Anne-Sophie Bellouin ◽  
C??cile Boscher ◽  
Corinne Lejus ◽  
Jean-Christophe Roz??
Keyword(s):  
Molecular Weight ◽  
Pilot Study ◽  
Hydroxyethyl Starch ◽  
Plasma Volume ◽  
Volume Expansion ◽  
Plasma Volume Expansion

Epidural Anesthesia, Hypotension, and Changes in Intravascular Volume

2004 ◽  
Vol 100 (2) ◽  
pp. 281-286 ◽  
Author(s):  
Kathrine Holte ◽  
Nicolai B. Foss ◽  
Christer Svensén ◽  
Claus Lund ◽  
Jan L. Madsen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Kinetic Analysis ◽  
Hydroxyethyl Starch ◽  
Plasma Volume ◽  
Epidural Anesthesia ◽  
Thoracic Epidural Anesthesia ◽  
Common Side Effect ◽  
Hemodynamic Effects ◽  
Thoracic Epidural ◽  
Per Se

Background The most common side effect of epidural or spinal anesthesia is hypotension with functional hypovolemia prompting fluid infusions or administration of vasopressors. Short-term studies (20 min) in patients undergoing lumbar epidural anesthesia suggest that plasma volume may increase when hypotension is present, which may have implications for the choice of treatment of hypotension. However, no long-term information or measurements of plasma volumes with or without hypotension after epidural anesthesia are available. Methods In 12 healthy volunteers, the authors assessed plasma (125I-albumin) and erythrocyte (51Cr-EDTA) volumes before and 90 min after administration of 10 ml bupivacaine, 0.5%, via a thoracic epidural catheter (T7-T10). After 90 min (t = 90), subjects were randomized to administration of fluid (7 ml/kg hydroxyethyl starch) or a vasopressor (0.2 mg/kg ephedrine), and 40 min later (t = 130), plasma and erythrocyte volumes were measured. At the same time points, mean corpuscular volume and hematocrit were measured. Systolic and diastolic blood pressure, heart rate, and hemoglobin were measured every 5 min throughout the study. Volume kinetic analysis was performed for the volunteers receiving hydroxyethyl starch. Results Plasma volume did not change per se after thoracic epidural anesthesia despite a decrease in blood pressure. Plasma volume increased with fluid administration but remained unchanged with vasopressors despite that both treatments had similar hemodynamic effects. Hemoglobin concentrations were not significantly altered by the epidural blockade or ephedrine administration but decreased significantly after hydroxyethyl starch administration. Volume kinetic analysis showed that the infused fluid expanded a rather small volume, approximately 1.5 l. The elimination constant was 56 ml/min. Conclusions Thoracic epidural anesthesia per se does not lead to changes in blood volumes despite a reduction in blood pressure. When fluid is infused, there is a dilution, and the fluid initially seems to be located centrally. Because administration of hydroxyethyl starch and ephedrine has similar hemodynamic effects, the latter may be preferred in patients with cardiopulmonary diseases in which perioperative fluid overload is undesirable.

Effect of Hydroxyethyl Starch and Dextran on Plasma Volume and Blood Hemostasis and Coagulation

1984 ◽  
Vol 24 (7) ◽  
pp. 273-282 ◽  
Author(s):  
K. KORTTILA ◽  
P. GRÖHN ◽  
A. GORDIN ◽  
S. SUNDBERG ◽  
H. SALO ◽  
...  
Keyword(s):  
Hydroxyethyl Starch ◽  
Plasma Volume

Development and characterization of amphiphilic hydroxyethyl starch derivatives

2016 ◽  
Vol 38 (3) ◽  
pp. 339-346
Author(s):  
Sheng Zhong ◽  
Shufen Zhang ◽  
Benzhi Ju ◽  
Kai Yang
Keyword(s):  
Hydroxyethyl Starch ◽  
Starch Derivatives

Hydroxyethyl starch 130/0.42/6:1 for perioperative plasma volume replacement in 1130 children: results of an European prospective multicenter observational postauthorization safety study (PASS)

2011 ◽  
Vol 22 (4) ◽  
pp. 371-378 ◽  
Author(s):  
Robert Sümpelmann ◽  
Franz-Josef Kretz ◽  
Robert Luntzer ◽  
Thomas G. de Leeuw ◽  
Vladimir Mixa ◽  
...  
Keyword(s):  
Hydroxyethyl Starch ◽  
Plasma Volume ◽  
Volume Replacement ◽  
Safety Study
Sign in / Sign up

Export Citation Format

Share Document