scholarly journals Is comorbid depression related to weight gain during treatment of anorexia nervosa?

IJEDO ◽  
2020 ◽  
pp. 41-42
Author(s):  
Meule ◽  
Voderholzer ◽  
Schlegl
Keyword(s):  
Anorexia Nervosa ◽  
Weight Gain ◽  
Comorbid Depression

scholarly journals Comorbid depression as a negative predictor of weight gain during treatment of anorexia nervosa: A systematic scoping review

2020 ◽  
Vol 28 (6) ◽  
pp. 605-619
Author(s):  
Mia Eskild‐Jensen ◽  
René K. Støving ◽  
Christopher F. Flindt ◽  
Magnus Sjogren
Keyword(s):  
Anorexia Nervosa ◽  
Weight Gain ◽  
Scoping Review ◽  
Comorbid Depression ◽  
Negative Predictor

scholarly journals Overcoming limitations of self-report: an assessment of fear of weight gain in anorexia nervosa and healthy controls using implicit association tests

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Tiana Borgers ◽  
Nathalie Krüger ◽  
Silja Vocks ◽  
Jennifer J. Thomas ◽  
Franziska Plessow ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Weight Gain ◽  
Normal Weight ◽  
Self Report ◽  
Healthy Controls ◽  
Drive For Thinness ◽  
Implicit Association ◽  
Association Tests ◽  
Implicit Assessment ◽  
Fear Of Weight Gain

Abstract Background Fear of weight gain is a characteristic feature of anorexia nervosa (AN), and reducing this fear is often a main target of treatment. However, research shows that 20% of individuals with AN do not report fear of weight gain. Studies are needed that evaluate the centrality of fear of weight gain for AN with a method less susceptible to deception than self-report. Methods We approximated implicit fear of weight gain by measuring implicit drive for thinness using implicit association tests (IATs). We asked 64 participants (35 AN, 29 healthy controls [HCs]) to categorize statements as pro-dieting vs. non-dieting and true vs. false in a questionnaire-based IAT, and pictures of underweight vs. normal-weight models and positive vs. negative words in a picture-based IAT using two response keys. We tested for associations between implicit drive for thinness and explicitly reported psychopathology within AN as well as group differences between AN and HC groups. Results Correlation analyses within the AN group showed that higher implicit drive for thinness was associated with more pronounced eating disorder-specific psychopathology. Furthermore, the AN group showed a stronger implicit drive for thinness than HCs in both IATs. Conclusion The results highlight the relevance of considering fear of weight gain as a continuous construct. Our implicit assessment captures various degrees of fear of weight gain in AN, which might allow for more individually tailored interventions in the future.

scholarly journals Antimicrobial peptides in patients with anorexia nervosa: comparison with healthy controls and the impact of weight gain

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Marie-Christin Bendix ◽  
Michael Stephan ◽  
Mariel Nöhre ◽  
Wally Wünsch-Leiteritz ◽  
Hagen Schmidt ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Weight Gain ◽  
Antimicrobial Peptides ◽  
Pathogenic Bacteria ◽  
Innate Immune ◽  
Effect Sizes ◽  
Healthy Controls ◽  
Clinical Observations ◽  
The Impact

AbstractClinical observations show that patients with anorexia nervosa (AN) are surprisingly free from infectious diseases. There is evidence from studies in Drosophila melanogaster that starvation leads to an increased expression of antimicrobial peptides (AMPs). AMPs are part of the innate immune system and protect human surfaces from colonization with pathogenic bacteria, viruses and fungi. We compared the expression of AMPs between patients with AN and healthy controls (HC) and investigated the influence of weight gain. Using a standardized skin rinsing method, quantitative determination of the AMPs psoriasin and RNase 7 was carried out by ELISA. Even though non-significant, effect sizes revealed slightly higher AMP concentrations in HC. After a mean weight gain of 2.0 body mass index points, the concentration of psoriasin on the forehead of patients with AN increased significantly. We could not confirm our hypotheses of higher AMP concentrations in patients with AN that decrease after weight gain. On the contrary, weight gain seems to be associated with increasing AMP concentrations.

Vitamin D status in young Swedish women with anorexia nervosa during intensive weight gain therapy

2016 ◽  
Vol 56 (6) ◽  
pp. 2061-2067 ◽  
Author(s):  
Anna Svedlund ◽  
Cecilia Pettersson ◽  
Bojan Tubic ◽  
Per Magnusson ◽  
Diana Swolin-Eide
Keyword(s):  
Vitamin D ◽  
Anorexia Nervosa ◽  
Weight Gain ◽  
Vitamin D Status

Anorexia Nervosa in an Elderly Woman

2001 ◽  
Vol 35 (2) ◽  
pp. 246-248 ◽  
Author(s):  
Rosalie Hill ◽  
Christopher Haslett ◽  
Shailesh Kumar
Keyword(s):  
Anorexia Nervosa ◽  
Depressive Symptoms ◽  
Electroconvulsive Therapy ◽  
Clinical Picture ◽  
Elderly Woman ◽  
Eating Behaviour ◽  
The Elderly ◽  
Aggressive Treatment ◽  
Comorbid Depression ◽  
First Onset

Objective: To demonstrate a case of anorexia nervosa in the elderly and to highlight the need for broadening of current diagnostic criteria. Clinical picture: First onset of anorexia nervosa in a 72-year-old woman following bereavement of her husband. Treatment: Nine treatments of electroconvulsive therapy. Outcome: Treatment resulted in remission of the depressive symptoms and improvement of eating behaviour. Conclusions: Anorexia nervosa does occur in the elderly and can be difficult to detect. Where comorbid depression exists it requires aggressive treatment.

scholarly journals The Gut Microbiome Derived From Anorexia Nervosa Patients Impairs Weight Gain and Behavioral Performance in Female Mice

Endocrinology ◽  
2019 ◽  
Vol 160 (10) ◽  
pp. 2441-2452 ◽  
Author(s):  
Tomokazu Hata ◽  
Noriyuki Miyata ◽  
Shu Takakura ◽  
Kazufumi Yoshihara ◽  
Yasunari Asano ◽  
...  
Keyword(s):  
Body Weight ◽  
Anorexia Nervosa ◽  
Weight Gain ◽  
Food Intake ◽  
Brain Stem ◽  
Body Weight Gain ◽  
Field Tests ◽  
Compulsive Behavior ◽  
The Brain ◽  
Poor Weight Gain

Abstract Anorexia nervosa (AN) results in gut dysbiosis, but whether the dysbiosis contributes to AN-specific pathologies such as poor weight gain and neuropsychiatric abnormalities remains unclear. To address this, germ-free mice were reconstituted with the microbiota of four patients with restricting-type AN (gAN mice) and four healthy control individuals (gHC mice). The effects of gut microbes on weight gain and behavioral characteristics were examined. Fecal microbial profiles in recipient gnotobiotic mice were clustered with those of the human donors. Compared with gHC mice, gAN mice showed a decrease in body weight gain, concomitant with reduced food intake. Food efficiency ratio (body weight gain/food intake) was also significantly lower in gAN mice than in gHC mice, suggesting that decreased appetite as well as the capacity to convert ingested food to unit of body substance may contribute to poor weight gain. Both anxiety-related behavior measured by open-field tests and compulsive behavior measured by a marble-burying test were increased only in gAN mice but not in gHC mice. Serotonin levels in the brain stem of gAN mice were lower than those in the brain stem of gHC mice. Moreover, the genus Bacteroides showed the highest correlation with the number of buried marbles among all genera identified. Administration of Bacteroides vulgatus reversed compulsive behavior but failed to exert any substantial effect on body weight. Collectively, these results indicate that AN-specific dysbiosis may contribute to both poor weight gain and mental disorders in patients with AN.

Assessment of brain function in adolescent anorexia nervosa before and after weight gain

1997 ◽  
Vol 19 (1) ◽  
pp. 20-33 ◽  
Author(s):  
Susan J. Bradley ◽  
Margot J. Taylor ◽  
Joanne F. Rovet ◽  
Eudice Goldberg ◽  
Jane Hood ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Weight Gain ◽  
Brain Function ◽  
Before And After ◽  
Adolescent Anorexia Nervosa

Rate of Weight Gain of Inpatients with Anorexia Nervosa Under Two Behavioral Contracts

PEDIATRICS ◽  
1994 ◽  
Vol 93 (6) ◽  
pp. 989-991
Author(s):  
Mary V. Solanto ◽  
Stanley Hertz ◽  
Marc S. Jacobson ◽  
Neville H. Golden ◽  
Lenore Heller
Keyword(s):  
Anorexia Nervosa ◽  
Weight Gain ◽  
Female Gender ◽  
Analysis Of Covariance ◽  
Adolescent Medicine ◽  
Medical Illness ◽  
Chronic Medical Illness ◽  
Criterion Weight ◽  
Behavioral Contracts

Objective. To ascertain the rate of weight gain of inpatients with anorexia nervosa under two behavioral contracts, differing in criterion weight gain required to earn increasing privileges. Design. Follow-up comparison of cohorts receiving different interventions. Setting. Eating disorders service, operating on a general adolescent medicine unit. Patients. Patients admitted consecutively who met the following criteria: (1) weight at least 15% less than that expected for age, sex, and height; (2) female gender; (3) absence of chronic medical illness; (4) hospital stay of at least 28 days. Twenty-two patients meeting these criteria were treated between July 1987 and October 1988, when contract 1 was in effect. This cohort of patients was compared with a group of 31 patients, also meeting the these criteria, who were treated between November 1988 and December 1991, when contract 2 was in effect. Interventions. The behavioral contract, signed by the patient on admission, specifies the minimum 4-day weight gain necessary to earn increasing ward privileges, such as use of phone, frequency of visits, etc. Contracts 1 and 2 differed only in the 4-day weight gain criterion: 0.8 lb (0.36 kg) and 1.2 lb (0.55 kg), respectively. Results. The results of analysis of covariance, with admission weight as the covariate, revealed a significant interaction between contract and day, such that patients receiving contract 2 gained weight more rapidly (0.36 lb/d) than those receiving contract 1 (0.20 lb/d). There was no confounding difference between groups in the use of psychotropic medication, and no complications of refeeding in either group. Conclusion. Increasing the 4-day criterion weight gain from 0.8 to 12 lb in a behavioral contracting intervention was associated with a significant increase in the rate of weight gain, without an accompanying increase in complications of refeeding. This result simultaneously: (a) provides support for the efficacy of behavioral contracting and (b) reveals malleability in the rate of gain based on the targeted gain specified in the contract.

Weight gain in anorexia nervosa

1981 ◽  
Vol 34 (4) ◽  
pp. 599-599 ◽  
Author(s):  
George G. Graham
Keyword(s):  
Anorexia Nervosa ◽  
Weight Gain
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