scholarly journals Human Infection with Eurasian Avian-Like Swine Influenza A(H1N1) Virus, the Netherlands, September 2019

2021 ◽  
Vol 27 (3) ◽  
pp. 939-943
Author(s):  
Anna Parys ◽  
Elien Vandoorn ◽  
Jacqueline King ◽  
Annika Graaf ◽  
Anne Pohlmann ◽  
...  
Virology ◽  
2013 ◽  
Vol 446 (1-2) ◽  
pp. 49-55 ◽  
Author(s):  
Rongqiang Zu ◽  
Libo Dong ◽  
Xian Qi ◽  
Dayan Wang ◽  
Shumei Zou ◽  
...  

2003 ◽  
Vol 148 (4) ◽  
pp. 793-802 ◽  
Author(s):  
V. Gregory ◽  
M. Bennett ◽  
Y. Thomas ◽  
L. Kaiser ◽  
W. Wunderli ◽  
...  

2010 ◽  
Vol 201 (8) ◽  
pp. 1178-1182 ◽  
Author(s):  
Nathalie Bastien ◽  
Nick A. Antonishyn ◽  
Ken Brandt ◽  
Christine E. Wong ◽  
Khami Chokani ◽  
...  

2009 ◽  
Vol 14 (21) ◽  
Author(s):  
A Solovyov ◽  
G Palacios ◽  
T Briese ◽  
W I Lipkin ◽  
R Rabadan

In March and April 2009, a new strain of influenza A(H1N1) virus has been isolated in Mexico and the United States. Since the initial reports more than 10,000 cases have been reported to the World Health Organization, all around the world. Several hundred isolates have already been sequenced and deposited in public databases. We have studied the genetics of the new strain and identified its closest relatives through a cluster analysis approach. We show that the new virus combines genetic information related to different swine influenza viruses. Segments PB2, PB1, PA, HA, NP and NS are related to swine H1N2 and H3N2 influenza viruses isolated in North America. Segments NA and M are related to swine influenza viruses isolated in Eurasia.


2009 ◽  
Vol 181 (3-4) ◽  
pp. 159-163 ◽  
Author(s):  
J. Cutler ◽  
E. Schleihauf ◽  
T. F. Hatchette ◽  
B. Billard ◽  
G. Watson-Creed ◽  
...  

2013 ◽  
Vol 19 (10) ◽  
pp. 1709-1711 ◽  
Author(s):  
Da-Yan Wang ◽  
Shun-Xiang Qi ◽  
Xi-Yan Li ◽  
Jun-Feng Guo ◽  
Min-Ju Tan ◽  
...  

2010 ◽  
Vol 84 (9) ◽  
pp. 4194-4203 ◽  
Author(s):  
Jessica A. Belser ◽  
Debra A. Wadford ◽  
Claudia Pappas ◽  
Kortney M. Gustin ◽  
Taronna R. Maines ◽  
...  

ABSTRACT The pandemic H1N1 virus of 2009 (2009 H1N1) continues to cause illness worldwide, primarily in younger age groups. To better understand the pathogenesis of these viruses in mammals, we used a mouse model to evaluate the relative virulence of selected 2009 H1N1 viruses and compared them to a representative human triple-reassortant swine influenza virus that has circulated in pigs in the United States for over a decade preceding the current pandemic. Additional comparisons were made with the reconstructed 1918 virus, a 1976 H1N1 swine influenza virus, and a highly pathogenic H5N1 virus. Mice were inoculated intranasally with each virus and monitored for morbidity, mortality, viral replication, hemostatic parameters, cytokine production, and lung histology. All 2009 H1N1 viruses replicated efficiently in the lungs of mice and possessed a high degree of infectivity but did not cause lethal disease or exhibit extrapulmonary virus spread. Transient weight loss, lymphopenia, and proinflammatory cytokine and chemokine production were present following 2009 H1N1 virus infection, but these levels were generally muted compared with a triple-reassortant swine virus and the 1918 virus. 2009 H1N1 viruses isolated from fatal cases did not demonstrate enhanced virulence in this model compared with isolates from mild human cases. Histologically, infection with the 2009 viruses resulted in lesions in the lung varying from mild to moderate bronchiolitis with occasional necrosis of bronchiolar epithelium and mild to moderate peribronchiolar alveolitis. Taken together, these studies demonstrate that the 2009 H1N1 viruses exhibited mild to moderate virulence in mice compared with highly pathogenic viruses.


2018 ◽  
Vol 33 (3) ◽  
pp. 282-286 ◽  
Author(s):  
Jian-Feng Xie ◽  
Yan-Hua Zhang ◽  
Lin Zhao ◽  
Wen-Qiong Xiu ◽  
Hong-Bin Chen ◽  
...  

1995 ◽  
Vol 76 (10) ◽  
pp. 2539-2547 ◽  
Author(s):  
M. H. Bikour ◽  
E. H. Frost ◽  
S. Deslandes ◽  
B. Talbot ◽  
Y. Elazhary

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