scholarly journals Concomitant Multidrug-resistant Pulmonary Tuberculosis and Susceptible Tuberculous Meningitis

2014 ◽  
Vol 20 (3) ◽  
pp. 506-507 ◽  
Author(s):  
Christine Bernard ◽  
Florence Brossier ◽  
Mathilde Fréchet-Jachym ◽  
Philippe C. Morand ◽  
Sophie Coignard ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Tuberculous Meningitis ◽  
Multidrug Resistant

scholarly journals EXTRAPLEURAL PNEUMOLYSIS FOR CAVITARY PULMONARY TUBERCULOSIS TREATMENT

2020 ◽  
pp. 15-20
Author(s):  
P. G. Gadzhieva ◽  
D. B. Giller ◽  
A. A. Glotov ◽  
O. Sh. Kesaev ◽  
V. V. Koroev ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
Pathological Process ◽  
Tuberculosis Treatment ◽  
Long Term Results ◽  
Filling Material ◽  
Different Types ◽  
Positive Effect ◽  
Observation Period

Objective. To increase efficiency of cavitary pulmonary tuberculosis treatment by developing modern indications and technology of extrapleural pneumolysis with filling material.Material and methods. We reviewed 25 patients with cavitary pulmonary tuberculosis and bacterial excretion who had undergone extrapleural pneumolysis with different types of filling material in 2004–2015. In 16 cases, we performed surgery in patients with one lung.Results. 56% of operated patients demonstrated extensively drug-resistant TB, 40% had multidrug-resistant TB. Cavities were closed and bacterial excretion ceased in 92% of patients at discharge. Long-term results with observation period from 1 to 12 years were analyzed in 24 patients, 17 (71%) of them had complete clinical efficacy.Conclusion. Extrapleural pneumolysis is a mini-invasive surgical treatment that can prove positive effect in patients with non-fibrotic changes in a cavity wall and pathological process in upper parts of the lungs. 

scholarly journals EXPERIENCE OF SURGICAL TREATMENT OF MULTIDRUG RESISTANT PULMONARY TUBERCULOSIS IN CHILDREN АND TEENAGERS

2018 ◽  
Vol 102 (4) ◽  
pp. 48-52
Author(s):  
М. S. Opanasenko ◽  
◽  
О. V. Tereshkovуch ◽  
O. І. Belogortseva ◽  
Т.V. Kyrylova ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Pulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
Tuberculosis In Children

scholarly journals Risk Factors for Multidrug-Resistant Tuberculosis among Patients with Pulmonary Tuberculosis at the Central Chest Institute of Thailand

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0139986 ◽  
Author(s):  
Charoen Chuchottaworn ◽  
Vipa Thanachartwet ◽  
Piamlarp Sangsayunh ◽  
Thu Zar Myint Than ◽  
Duangjai Sahassananda ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis

scholarly journals Evaluation of an In-House-Developed Radioassay Kit for Antibody Detection in Cases of Pulmonary Tuberculosis and Tuberculous Meningitis

2002 ◽  
Vol 9 (5) ◽  
pp. 987-993
Author(s):  
M. Kameswaran ◽  
K. Shetty ◽  
M. K. Ray ◽  
M. A. Jaleel ◽  
G. V. Kadival
Keyword(s):  
Pulmonary Tuberculosis ◽  
Tuberculous Meningitis ◽  
Clinical Sample ◽  
Antibody Detection ◽  
Serum Samples ◽  
Early Administration ◽  
Course Of Disease ◽  
Control Serum ◽  
Immunodeficiency Virus ◽  
User Friendly

ABSTRACT A radioassay for the detection of antitubercular antibody has been developed. The technique involves the addition of 125I-labeled Mycobacterium tuberculosis antigen as a tracer, diluted clinical sample (serum or cerebrospinal fluid [CSF]), and heat-inactivated Staphylococcus aureus to capture the antibody, incubation for 4 h, and quantitation of the amount of antibody present in the sample. A total of 330 serum samples from patients with pulmonary tuberculosis and 138 control serum samples from individuals who were vaccinated with M. bovis BCG and from patients with pulmonary disorders of nontubercular origin were analyzed. Also, 26 CSF samples from patients with tuberculous meningitis and 24 CSF samples as controls from patients with central nervous system disorders of nontuberculous origin were analyzed. Sensitivities of 80 and 73% were observed for patients with pulmonary tuberculosis and tuberculous meningitis, respectively, and specificities of 90 and 88% were seen for the two groups of patients, respectively. The sensitivity was lower, however, for human immunodeficiency virus-infected patients coinfected with M. tuberculosis. The control population could be differentiated from the patient population. This assay is rapid and user friendly and, with its good sensitivity and specificity, should benefit the population by providing diagnoses early in the course of disease and, hence, permit the early administration of appropriate chemotherapy.

Treatment of multidrug-resistant pulmonary tuberculosis with delamanid based on Japanese guideline recommendations

2020 ◽  
Vol 58 (2) ◽  
pp. 110-116 ◽  
Author(s):  
Masao Okumura ◽  
Takashi Yoshiyama ◽  
Hideo Ogata ◽  
Atsuyuki Kurashima ◽  
Kozo Yoshimori ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
Japanese Guideline
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