scholarly journals Use of Malaria Rapid Diagnostic Test to Identify Plasmodium knowlesi Infection

2008 ◽  
Vol 14 (11) ◽  
pp. 1750-1752 ◽  
Author(s):  
Thomas F. McCutchan
Keyword(s):  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Plasmodium Knowlesi ◽  
Malaria Rapid Diagnostic Test

scholarly journals Malaria rapid diagnostic test (HRP2/pLDH) positivity, incidence, care accessibility and impact of community WASH Action programme in DR Congo: mixed method study involving 625 households

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Nlandu Roger Ngatu ◽  
Basilua Andre Muzembo ◽  
Nattadech Choomplang ◽  
Sakiko Kanbara ◽  
Roger Wumba ◽  
...  
Keyword(s):  
Action Research ◽  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Mixed Method ◽  
Malaria Incidence ◽  
Control Site ◽  
Malaria Rapid Diagnostic Test ◽  
Post Intervention ◽  
Referral Hospitals ◽  
Action Programme

Abstract Background Malaria is one of the most prevalent and deadliest illnesses in sub-Saharan Africa. Despite recent gains made towards its control, many African countries still have endemic malaria transmission. This study aimed to assess malaria burden at household level in Kongo central province, Democratic Republic of Congo (DRC), and the impact of community participatory Water, Sanitation and Hygiene (WASH) Action programme. Methods Mixed method research was conducted in two semi-rural towns, Mbanza-Ngungu (a WASH action site) and Kasangulu (a WASH control site) in DRC between 1 January 2017 through March 2018, involving 625 households (3,712 household members). Baseline and post-intervention malaria surveys were conducted with the use of World Bank/WHO Malaria Indicator Questionnaire. An action research consisting of a six-month study was carried out which comprised two interventions: a community participatory WASH action programme aiming at eliminating mosquito breeding areas in the residential environment and a community anti-malaria education campaign. The latter was implemented at both study sites. In addition, baseline and post-intervention malaria rapid diagnostic test (RDT) was performed among the respondents. Furthermore, a six-month hospital-based epidemiological study was conducted at selected referral hospitals at each site from 1 January through June 2017 to determine malaria trend. Results Long-lasting insecticide-treated net (LLIN) was the most commonly used preventive measure (55%); 24% of households did not use any measures. Baseline malaria survey showed that 96% of respondents (heads of households) reported at least one episode occurring in the previous six months; of them only 66.5% received malaria care at a health setting. In the Action Research, mean incident household malaria cases decreased significantly at WASH action site (2.3 ± 2.2 cases vs. 1.2 ± 0.7 cases, respectively; p < 0.05), whereas it remained unchanged at the Control site. Similar findings were observed with RDT results. Data collected from referral hospitals showed high malaria incidence rate, 67.4%. Low household income (ORa = 2.37; 95%CI: 1.05–3.12; p < 0.05), proximity to high risk area for malaria (ORa = 5.13; 95%CI: 2–29-8.07; p < 0.001), poor WASH (ORa = 4.10; 95%CI: 2.11–7.08; p < 0.001) were predictors of household malaria. Conclusion This research showed high prevalence of positive malaria RDT among the responders and high household malaria incidence, which were reduced by a 6-month WASH intervention. DRC government should scale up malaria control strategy by integrating efficient indoor and outdoor preventive measures and improve malaria care accessibility.

scholarly journals Clinical overlap between malaria and pneumonia: can malaria rapid diagnostic test play a role?

2011 ◽  
Vol 5 (03) ◽  
pp. 199-203 ◽  
Author(s):  
Kingsley Nnanna Ukwaja ◽  
Olufemi B Aina ◽  
Ademola A Talabi
Keyword(s):  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Diagnostic Tests ◽  
Health Centre ◽  
Rapid Diagnostic Tests ◽  
Case Definition ◽  
Sub Saharan Africa ◽  
Malaria Rapid Diagnostic Test ◽  
Chi Square ◽  
Symptom Overlap

Introduction: Malaria and pneumonia account for 40% of mortality among children under five years of age in sub-Saharan Africa. Due to lack of diagnostic facilities, their management is based on the integrated management of childhood illnesses (IMCI) strategy. Symptoms of malaria and pneumonia overlap in African children, necessitating dual IMCI classifications at health centres and treatment with both antibiotics and antimalarials. This study determined the prevalence of malaria-pneumonia symptom overlap and confirmed the diagnosis of malaria in these cases using a rapid diagnostic test. Methodology: Consecutive consultations of 1,216 children (two months to five years old) were documented over a three-month period in a comprehensive health centre. Malaria rapid diagnostic tests were conducted only for children who had symptom overlap. Results: Of the 1,216 children enrolled, 1,090 (90%) reported cough or fever. Among the children fulfilling the malaria case definition, 284 (30%) also met the pneumonia case definition. Twenty-three percent (284) of all children enrolled met the criteria for both malaria and pneumonia. However, only 130 (46%) of them had a positive result for malaria using a malaria rapid diagnostic test. During a malaria-pneumonia overlap, female children (chi-square 5.9, P = 0.01) and children ≥ one year (chi-square 4.8, P = 0.003) were more likely to seek care within two days of fever. Conclusion: Dual treatment with antimalarials and antibiotics in children with malaria-pneumonia overlap may result in unnecessary over-prescription of antimalarial medications. Use of rapid diagnostic tests in their management can potentially avoid over-prescribing of malaria medications.

scholarly journals Malaria Rapid Diagnostic Test (RDTs)

2018 ◽  
Vol 06 (04) ◽  
Author(s):  
Emmanuel Ifeanyi Obeagu ◽  
Chijioke UO ◽  
Ekelozie IS
Keyword(s):  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Malaria Rapid Diagnostic Test

scholarly journals Genetic variation of pfhrp2 in Plasmodium falciparum isolates from Yemen and the performance of HRP2-based malaria rapid diagnostic test

2015 ◽  
Vol 8 (1) ◽  
Author(s):  
Wahib M. Atroosh ◽  
Hesham M. Al-Mekhlafi ◽  
Adel Al-Jasari ◽  
Hany Sady ◽  
Ahmed K. Al-Delaimy ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Genetic Variation ◽  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Malaria Rapid Diagnostic Test
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