Animal Cell Diagram

2018 ◽  
Author(s):  
Daniel Nelson
Keyword(s):  
Animal Cell

scholarly journals Preliminary Techno-Economic Assessment of Animal Cell-Based Meat

Foods ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 3
Author(s):  
Derrick Risner ◽  
Fangzhou Li ◽  
Jason S. Fell ◽  
Sara A. Pace ◽  
Justin B. Siegel ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Chemical Engineering ◽  
Animal Cell ◽  
Economic Assessment ◽  
The United States ◽  
Economic Viability ◽  
Monoclonal Antibody Production ◽  
Technological Performance ◽  
Low Volume ◽  
Cost Factors

Interest in animal cell-based meat (ACBM) or laboratory-grown meat has been increasing; however, the economic viability of these potential products has not been thoroughly vetted. Recent studies suggest monoclonal antibody production technology can be adapted for the industrialization of ACBM production. This study provides a scenario-based assessment of the projected cost per kilogram of ACBM produced in the United States based on cellular metabolic requirements and process/chemical engineering conventions. A sensitivity analysis of the model identified the nine most influential cost factors for ACBM production out of 67 initial parameters. The results indicate that technological performance will need to approach technical limits for ACBM to achieve profitably as a commodity. However, the model also suggests that low-volume high-value specialty products could be viable based on current technology.

scholarly journals Evidence for an essential role of long chain acyl-CoA synthetase in animal cell proliferation

1991 ◽  
Vol 266 (7) ◽  
pp. 4214-4219
Author(s):  
H Tomoda ◽  
K Igarashi ◽  
J C Cyong ◽  
S Omura
Keyword(s):  
Cell Proliferation ◽  
Essential Role ◽  
Animal Cell ◽  
Chain Acyl ◽  
Long Chain

Simulation of Cell Cycle Dependent Growth and Metabolism in Animal Cell Fermentation

1995 ◽  
Vol 28 (3) ◽  
pp. 326-329
Author(s):  
B. Szperalski ◽  
F. Geipel ◽  
U. Behrendt ◽  
J. Wahl
Keyword(s):  
Cell Cycle ◽  
Animal Cell ◽  
Dependent Growth ◽  
Cycle Dependent

scholarly journals Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteins

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alexander Pralow ◽  
Alexander Nikolay ◽  
Arnaud Leon ◽  
Yvonne Genzel ◽  
Erdmann Rapp ◽  
...  
Keyword(s):  
Zika Virus ◽  
Animal Cell ◽  
Gradient Centrifugation ◽  
Viral Envelope ◽  
Protein Glycosylation ◽  
High Yield ◽  
Structural Protein ◽  
Site Specific ◽  
E Protein ◽  
The Impact

AbstractHere, we present for the first time, a site-specific N-glycosylation analysis of proteins from a Brazilian Zika virus (ZIKV) strain. The virus was propagated with high yield in an embryo-derived stem cell line (EB66, Valneva SE), and concentrated by g-force step-gradient centrifugation. Subsequently, the sample was proteolytically digested with different enzymes, measured via a LC–MS/MS-based workflow, and analyzed in a semi-automated way using the in-house developed glyXtoolMS software. The viral non-structural protein 1 (NS1) was glycosylated exclusively with high-mannose structures on both potential N-glycosylation sites. In case of the viral envelope (E) protein, no specific N-glycans could be identified with this method. Nevertheless, N-glycosylation could be proved by enzymatic de-N-glycosylation with PNGase F, resulting in a strong MS-signal of the former glycopeptide with deamidated asparagine at the potential N-glycosylation site N444. This confirmed that this site of the ZIKV E protein is highly N-glycosylated but with very high micro-heterogeneity. Our study clearly demonstrates the progress made towards site-specific N-glycosylation analysis of viral proteins, i.e. for Brazilian ZIKV. It allows to better characterize viral isolates, and to monitor glycosylation of major antigens. The method established can be applied for detailed studies regarding the impact of protein glycosylation on antigenicity and human pathogenicity of many viruses including influenza virus, HIV and corona virus.

An Animal Protection Sponsor's View of MEIC

1997 ◽  
Vol 25 (3) ◽  
pp. 343-345
Author(s):  
Ethel Thurston
Keyword(s):  
Gold Standard ◽  
Animal Cell ◽  
Scientific Evidence ◽  
In Vitro Cytotoxicity ◽  
In Vitro Tests ◽  
Blood Concentrations ◽  
Animal Protection ◽  
Animal Tests ◽  
Lethal Blood

The Multicenter Evaluation of In Vitro Cytotoxicity programme is most important to animal protection, since it has validated 64 in vitro tests using advanced human data for 50 chemicals as the “gold standard”. Therefore, it has been able to compare animal cell tests, human cell tests and whole-animal tests fairly with unbiased scientific evidence. Added bonuses have included the identification and development of missing in vitro information (“missing tests”), publication of time-related lethal blood concentrations for all 50 chemicals, and some preliminary plans to resolve the 50,000 untested (or poorly tested) chemicals in the chemical mountain.

scholarly journals Multiple Effects of Rifamycin Derivatives on Animal-Cell Metabolism of Macromolecules

1973 ◽  
Vol 35 (2) ◽  
pp. 251-258 ◽  
Author(s):  
Enzo Busiello ◽  
Adele Di Girolamo ◽  
Mario Di Girolamo ◽  
Lia Fischer-Fantuzzi ◽  
Cesare Vesco
Keyword(s):  
Animal Cell ◽  
Cell Metabolism
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