scholarly journals Effects of Compression on the Temperature Distribution of a Tissue-Mimicking Material During High-Intensity Focused Ultrasound (HIFU) Ablation

2013 ◽  
Author(s):  
Austin Robbins Roth
Keyword(s):  
Temperature Distribution ◽  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Hifu Ablation ◽  
Tissue Mimicking Material

Single-session high-intensity focused ultrasound (HIFU) ablation for benign thyroid nodules: a systematic review

2020 ◽  
Vol 17 (8) ◽  
pp. 759-771
Author(s):  
Eleftherios Spartalis ◽  
Sotirios P. Karagiannis ◽  
Nikolaos Plakopitis ◽  
Maria Anna Theodori ◽  
Dimosthenis Chrysikos ◽  
...  
Keyword(s):  
Systematic Review ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Thyroid Nodules ◽  
High Intensity Focused Ultrasound ◽  
Single Session ◽  
Hifu Ablation ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

scholarly journals V4-07 CONTRAST-ENHANCED ULTRASOUND (CEUS): EVALUATION OF HIGH INTENSITY FOCUSED ULTRASOUND (HIFU) ABLATION OF THE PROSTATE

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Andre Luis Abreu ◽  
Daniel Freitas ◽  
Daniel Park ◽  
Toshitaka Shin ◽  
Masakatsu Oishi ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Contrast Enhanced Ultrasound ◽  
Hifu Ablation ◽  
Contrast Enhanced

Immune response after high-intensity focused ultrasound ablation for H22 tumor

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 21169-21169 ◽  
Author(s):  
P. Zhou ◽  
M. Fu ◽  
J. Bai ◽  
Z. Wang ◽  
F. Wu
Keyword(s):  
Immune Response ◽  
Tumor Immunity ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Survival Rates ◽  
High Intensity Focused Ultrasound ◽  
Control Group ◽  
Term Survival ◽  
Hifu Ablation ◽  
Significant Difference

21169 Background: Previous results have shown that high intensity focused ultrasound (HIFU) ablation can potentially activate a host anti-tumor immunity. This study was to investigate whether acoustic cavitaion may enhance host immune responses after HIFU treatment for solid malignancy, and to explore the potential mechanisms regarding the enhanced anti-tumor immunity. Methods: (1) Tumor cell vaccine preparation: H22 cells were irradiated with HIFU (0.8MHz, 1050W/cm2, 90s); H22 cells were heated for one hour in 65°C water bath. (2) Animal study: 150 KM mice were randomly divided into three groups: control group, thermal group, and HIFU group. Each group had 50 mice for immune experiments. By using hypodermic injection, the mice in thermal group and HIFU group received either 0.2ml heat-treated H22 vaccine or 0.2ml HIFU-treated H22 vaccine in the left flank of each mouse. Those in control group received only injection with same amount of saline solution. The vaccination times were 4 sessions, once a week for 4 consecutive weeks. One week after last vaccination, each mouse was challenged with H22 tumor cells. All mice were followed up to observe the long-term survival in each group, and peripheral blood was collected to detect changes in T lymphocytes and their subsets by flow cytometry technique. Results: The tumor incidences and 6-week survival rates were observed 100% and 88% of mice in control group, 72.5% and 40% in thermal group, and 42.5% and 14% in HIFU group respectively. Compared to the values in either control group or thermal group, there was a significant decrease of tumor incidences and 6-week survival rates in HIFU group. The volume of tumor was obviously lower in HIFU group, and a significant difference was observed between HIFU group and thermal group or control group. Compared to the values in control group, there were a significant increase of CD4+ levels and CD4+/CD8+ ratio, and a significant decrease of CD8+ level in both HIFU group and thermal group. Conclusions: Antitumor immune response could be enhanced after HIFU ablation for H22 implanted tumor in mice, and acoustic cavitation could play an important role to stimulate host antitumor immune system. No significant financial relationships to disclose.

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