Dialogues in Clinical Neuroscience

10.31887/dcns ◽  
2020 ◽  
2021 ◽  
pp. 9-37
Author(s):  
Ayol Samuels ◽  
Matthew L. Baum ◽  
Joseph Luchsinger ◽  
Robert G. Mealer ◽  
Rachel A. Ross

Author(s):  
Julie Royo ◽  
Stephanie J. Forkel ◽  
Pierre Pouget ◽  
Michel Thiebaut de Schotten

2015 ◽  
Vol 46 (02) ◽  
pp. 088-097 ◽  
Author(s):  
Raneem Rajjoub ◽  
Carmelina Trimboli-Heidler ◽  
Amy Waldman ◽  
Robert Avery

2021 ◽  
Author(s):  
Frank Hillary ◽  
Sarah Rajtmajer

Abstract:This critical review discusses evidence for the replication crisis in the clinical neuroscience literature with focus on the size of the literature and how scientific hypotheses are framed and tested. We aim to reinvigorate discussions born from philosophy of science regarding falsification (see Popper, 1959;1962) but with hope to bring pragmatic application that might give real leverage to attempts to address scientific reproducibility. The surging publication rate has not translated to unparalleled scientific progress so the current “science-by-volume” approach requires new perspective for determining scientific ground truths. We describe an example from the network neurosciences in the study of traumatic brain injury where there has been little effort to refute two prominent hypotheses leading to a literature without resolution. Based upon this example, we discuss how building strong hypotheses and then designing efforts to falsify them can bring greater precision to the clinical neurosciences. With falsification as the goal, we can harness big data and computational power to identify the fitness of each theory to advance the neurosciences.


2021 ◽  
Author(s):  
David S. Warner ◽  
Michael M. Todd

David Warner, M.D., and Michael Todd, M.D., first met in 1985. They began working together at the University of Iowa (Iowa City, Iowa) a year later with a shared interest in both laboratory and clinical neuroscience—and in the operative care of neurosurgical patients. That collaboration has now lasted for 35 yr, resulting in more than 70 joint publications. More importantly, they have had the privilege of working together with close to 1,000 colleagues from around the world, in a dozen medical specialties. Their careers are an example of what can be accomplished by friendship, mutual commitment, persistence, and a willingness to join with others.


2021 ◽  
Author(s):  
Annakarina Mundorf ◽  
Sebastian Ocklenburg

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