scholarly journals Vitamin D Insufficiency Predicts Elevated Levels of Complement 3 Independent of Insulin Resistance and BMI

2017 ◽  
Vol 63 (3) ◽  
pp. 155-160 ◽  
Author(s):  
Reem M. AL HAJ AHMAD ◽  
Hayder A. AL-DOMI
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Vitamin D Insufficiency ◽  
Complement 3

scholarly journals Association of vitamin D insufficiency with adiposity and metabolic disorders in Brazilian adolescents

2013 ◽  
Vol 17 (4) ◽  
pp. 787-794 ◽  
Author(s):  
Renata MS Oliveira ◽  
Juliana F Novaes ◽  
Lorena M Azeredo ◽  
Ana Paula C Cândido ◽  
Isabel CG Leite
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Metabolic Disorders ◽  
Central City ◽  
Vitamin D Insufficiency ◽  
Model Assessment ◽  
Cross Sectional ◽  
Vitamin D Intake ◽  
Dietary Record

AbstractObjectiveThe present study aimed to evaluate the frequency of deficiency/insufficiency of vitamin D in adolescents and its relationship to overweight and metabolic disorders.DesignCross-sectional study. Nutritional status was assessed by BMI according to WHO recommendations. Dietary intake was evaluated using a 3 d dietary record. The biochemical evaluation comprised measurements of serum lipids, lipoproteins, glucose, insulin, calcidiol (25(OH)D) and parathyroid hormone. Insulin resistance was calculated using the homeostasis model assessment. Body composition and blood pressure were assessed.SettingFifteen schools (eight public and seven private) in the central city of Juiz de Fora, Brazil.SubjectsThe analysis included a study population of 160 adolescents (seventy-seven eutrophic and eighty-three overweight) aged 15 to 17 years.ResultsVitamin D deficiency and insufficiency was observed in 1·25 and 70·6 % of adolescents, respectively. Serum 25(OH)D levels were statistically lower in adolescents with weight excess, abdominal obesity, hypercholesterolaemia, higher levels of parathyroid hormone, insulin resistance, hyperinsulinaemia and hypertension (P < 0·05). Lower BMI and waist circumference were observed in the third (highest) tertile of vitamin D intake for all adolescents. The high prevalence of vitamin D insufficiency is primarily nutritional and reflects a low vitamin D intake.ConclusionsOur results support the negative association among serum 25(OH)D levels and vitamin D intake with non-skeletal outcomes in Brazilian adolescents. Vitamin D fortification of foods and/or the use of vitamin D supplements need to be considered to raise vitamin D intake in the adolescent population, even in a sunny country like Brazil.

scholarly journals Insulin Resistance and Vitamin D Deficiency in Patients With Chronic Kidney Disease Stage 2-3

2011 ◽  
pp. 149-155 ◽  
Author(s):  
K. ŠTEFÍKOVÁ ◽  
V. SPUSTOVÁ ◽  
Z. KRIVOŠÍKOVÁ ◽  
A. OKŠA ◽  
K. GAZDÍKOVÁ ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Insulin Sensitivity ◽  
Kidney Disease ◽  
Vitamin D Deficiency ◽  
Chronic Kidney Disease Stage ◽  
Vitamin D Insufficiency ◽  
Disease Stage ◽  
25 Oh Vitamin D

Vitamin D status and the relationship between serum 25(OH) vitamin D concentrations and the components of insulin resistance were examined in 120 patients with chronic kidney disease stage 2 and 3. Insulin sensitivity/resistance was calculated by the quantitative insulin sensitivity check index (QUICKI). In this analysis, the prevalence of insulin resistance was 42 %. Only 17 % of patients had serum 25(OH) vitamin D concentration in the recommended range (≥30 ng/ml), 42 % suffered from vitamin D insufficiency and 41 % had moderate vitamin D deficiency. Insulin resistance significantly correlated with serum 25(OH)D and 1,25(OH)2D concentrations, renal function and protein excretion rate. Our results support the increasing evidence that vitamin D deficiency may be one of the factors participating in the development of insulin resistance already in the early stages of chronic kidney disease.

Vitamin D insufficiency is associated with insulin resistance independently of obesity in primary schoolchildren. The healthy growth study

2018 ◽  
Vol 19 (5) ◽  
pp. 866-873 ◽  
Author(s):  
George Moschonis ◽  
Odysseas Androutsos ◽  
Toine Hulshof ◽  
Maria Dracopoulou ◽  
George P Chrousos ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Vitamin D Insufficiency ◽  
Growth Study ◽  
Primary Schoolchildren ◽  
Healthy Growth

scholarly journals Vitamin D insufficiency/deficiency is associated with insulin resistance in Brazilian children, regardless of body fat distribution

2017 ◽  
Vol 20 (16) ◽  
pp. 2878-2886 ◽  
Author(s):  
Luana Cupertino Milagres ◽  
Naruna Pereira Rocha ◽  
Mariana de Santis Filgueiras ◽  
Fernanda Martins de Albuquerque ◽  
Ana Paula Pereira Castro ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Representative Sample ◽  
Prevalence Ratio ◽  
Population Based ◽  
Vitamin D Insufficiency ◽  
Central Adiposity ◽  
Anthropometric Measures ◽  
Cross Sectional ◽  
Study Results

AbstractObjectiveTo assess the prevalence of vitamin D insufficiency and deficiency and its association with cardiometabolic risk factors, controlled by adiposity, in a representative sample of prepubescent children.DesignCross-sectional population-based study. Body composition was evaluated by dual-energy X-ray absorptiometry. Anthropometric measures and blood pressure were performed. Laboratory analyses were performed to determine the levels of vitamin D (25-hydroxyitamin D; 25(OH)D), glucose, insulin, serum lipids and intact parathyroid hormone. Dietary intake was assessed by three 24 h recalls.SettingViçosa, Minas Gerais, Brazil, 2015.SubjectsRepresentative sample of 378 children aged 8 and 9 years from urban schools.ResultsInadequate serum concentrations of 25(OH)D were diagnosed in more than half of the children and none of them met the recommended vitamin D intake. After adjusting for confounding factors in the multiple regression analysis, lower prevalence of insulin resistance and hypertriacylglycerolaemia was found in children with serum 25(OH)D levels ≥75 nmol/l (prevalence ratio=0·25; 95 % CI 0·08, 0·85) and ≥50 nmol/l (prevalence ratio=0·61; 95 % CI 0·37, 0·99), respectively. However, after adjusting for different indicators of adiposity, insulin resistance remained independently associated and the association with hypertriacylglycerolaemia was lost after adjusting for central adiposity. The prevalence of vitamin D insufficiency/deficiency was associated with the number of cardiometabolic alterations in children.ConclusionsThe study results showed that prevalence of vitamin D insufficiency/deficiency was high among the children and insulin resistance was the main cardiometabolic alteration associated with this condition, even in a tropical climate country such as Brazil.

scholarly journals 25(OH)D was Correlated with Increased Risk of Insulin Resistance, but Not Mediated by Adiponectin and hsCRP

2012 ◽  
Vol 4 (2) ◽  
pp. 84
Author(s):  
Anggi Kartikawati ◽  
Yani Lina ◽  
Andi Wijaya
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Cell Function ◽  
Resistance Index ◽  
High Sensitivity ◽  
Significant Negative Correlation ◽  
Vitamin D Insufficiency ◽  
Enzyme Linked Immunosorbent Assay ◽  
Cross Sectional ◽  
Increased Risk

BACKGROUND: Studies have shown that change of calcium and vitamin D homeostasis is associated with insulin resistance, decreased beta cell function, metabolic syndrome, glucose intolerance and diabetes. Evidence suggests that vitamin D insufficiency is inversely related to risk of metabolic disorders including type-2 Diabetes Mellitus (T2DM), although the underlying mechanisms are not yet understood. Hence, current study was conducted to investigate correlation between 25(OH)D and insulin resistance through adiponectin or High Sensitivity C-Reactive Protein (hsCRP) in centrally obese men.METHODS: This was a cross-sectional study involving 80 centrally obese men with waist circumference (WC) >90 cm and age 30-60 years. Total 25(OH)D concentration was measured by Enzyme-Linked Immunosorbent Assay (ELISA) method. Insulin resistance was calculated by HOMA model.RESULTS: This study showed there was no correlation of 25(OH)D-WC (r=0.006 and p=0.957), 25(OH)D-adiponectin (r=0.179 and p=0.111) abd 25(OH)D-hsCRP (r=-0.223 and p=0.334), but we observed  statistically significant negative correlation between 25(OH)D and insulin resistance index (HOMA-IR) (r=0.461 and p=0.041).CONCLUSIONS: We conclude that low 25(OH)D concentration was significantly associated with increased risk of insulin resistance. Since  the adiponectin or hsCRP was not correlated, the possible pathways need to be futher investigated.KEYWORDS: central obesity, 25(OH)D, adiponectin, hsCRP, insulin resistance (HOMA-IR)

scholarly journals Vitamin D Insufficiency is Associated with Greater Obesity‐Related Insulin Resistance

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Dian Sulistyoningrum ◽  
Danijela Gasevic ◽  
Timothy J Green ◽  
Scott A Lear ◽  
Angela M Devlin
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Vitamin D Insufficiency

Moderate alcohol intake is associated with decreased risk of insulin resistance among individuals with vitamin D insufficiency

Nutrition ◽  
2010 ◽  
Vol 26 (1) ◽  
pp. 100-105 ◽  
Author(s):  
Marty S. Player ◽  
Arch G. Mainous ◽  
Dana E. King ◽  
Vanessa A. Diaz ◽  
Charles J. Everett
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Alcohol Intake ◽  
Vitamin D Insufficiency ◽  
Moderate Alcohol Intake

scholarly journals Vitamin D insufficiency and insulin resistance in obese adolescents

2014 ◽  
Vol 5 (6) ◽  
pp. 166-189 ◽  
Author(s):  
Catherine A. Peterson ◽  
Aneesh K. Tosh ◽  
Anthony M. Belenchia
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Vitamin D Insufficiency ◽  
Obese Adolescents
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