Inhibitory Effects of Hyssop (Hyssopus officinalis) Extracts on Intestinal .ALPHA.-Glucosidase Activity and Postprandial Hyperglycemia

2003 ◽  
Vol 49 (5) ◽  
pp. 346-349 ◽  
Author(s):  
Hiroyuki MIYAZAKI ◽  
Hideyuki MATSUURA ◽  
Chikako YANAGIYA ◽  
Junya MIZUTANI ◽  
Masayoshi TSUJI ◽  
...  
Keyword(s):  
Postprandial Hyperglycemia ◽  
Inhibitory Effects ◽  
Glucosidase Activity ◽  
Alpha Glucosidase ◽  
Hyssopus Officinalis

Recent Developments in Alpha-Glucosidase Inhibitors for Management of Type-2 Diabetes: An Update

2019 ◽  
Vol 25 (23) ◽  
pp. 2510-2525 ◽  
Author(s):  
Bashir Usman ◽  
Neha Sharma ◽  
Saurabh Satija ◽  
Meenu Mehta ◽  
Manish Vyas ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Patient Compliance ◽  
Postprandial Hyperglycemia ◽  
Diabetic Patients ◽  
Poor Patient ◽  
Glucosidase Inhibitors ◽  
Poor Patient Compliance ◽  
Recent Developments ◽  
Alpha Glucosidase

The incidence of diabetes has increased globally in recent years and figures of diabetic patients were estimated to rise up to 642 million by 2040. The disorder is accompanied with various complications if not managed at the early stages, and interlinked high mortality rate and morbidity with time. Different classes of drugs are available for the management of type 2 diabetes but were having certain limitations of their safety. Alphaglucosidase is a family of enzyme originated from the pancreas which plays a role in the anabolism of 80-90% of carbohydrate consumed into glucose. This glucose is absorbed into the blood and results in frank postprandial hyperglycemia and worsens the conditions of diabetic patients which precipitate complications. Inhibition of these enzymes helps to prevent postprandial hyperglycemia and the formation of glycated end products. Alphaglucosidase inhibitors are reported to be more important in adequate control of type 2, but marketed drugs have various side effects, such as poor patient compliance and also expensive. This proves the needs for other class of drugs with better efficacy, safety, patient compliance and economic. In this review, we have emphasized the recent advances in the field of new alpha-glucosidase inhibitors with improved safety and pharmacological profile.

Alpha‐glucosidase activity in the rat epididymis under different physiological conditions

1997 ◽  
Vol 20 (2) ◽  
pp. 92-95 ◽  
Author(s):  
N. R. KALLA ◽  
S. KAUR ◽  
N. UJWAL ◽  
U. MEHTA ◽  
H. JOOS ◽  
...  
Keyword(s):  
Physiological Conditions ◽  
Glucosidase Activity ◽  
Rat Epididymis ◽  
Alpha Glucosidase

scholarly journals Inhibition of intestinal .ALPHA.-glucosidase and postprandial hyperglycemia by N-substituted moranoline derivatives.

1988 ◽  
Vol 11 (5) ◽  
pp. 356-362 ◽  
Author(s):  
Yoshiaki YOSHIKUNI ◽  
Yohji EZURE ◽  
Yoshiaki AOYAGI ◽  
Hiroshi ENOMOTO
Keyword(s):  
Postprandial Hyperglycemia ◽  
Alpha Glucosidase

Inhibitory Effect of Koji Aspergillus terreus on α-Glucosidase Activity and Postprandial Hyperglycemia

2007 ◽  
Vol 10 (18) ◽  
pp. 3131-3135 ◽  
Author(s):  
Rizna T. Dewi . ◽  
Yetty M. Iskandar . ◽  
M. Hanafi . ◽  
L.B.S. Kardono . ◽  
Marisa Angelina . ◽  
...  
Keyword(s):  
Aspergillus Terreus ◽  
Inhibitory Effect ◽  
Postprandial Hyperglycemia ◽  
Glucosidase Activity

scholarly journals IN VITRO EFFECT OF TERPENOIDS - RICH EXTRACT OF Momordica charantia ON ALPHA GLUCOSIDASE ACTIVITY

Revista Vitae ◽  
2018 ◽  
Vol 25 (3) ◽  
pp. 148-153 ◽  
Author(s):  
A. B. Sallau ◽  
◽  
R. N. Yakubu ◽  
S. M. Aliyu ◽  
A. Salihu ◽  
...  
Keyword(s):  
Momordica Charantia ◽  
Glucosidase Activity ◽  
Vitro Effect ◽  
Alpha Glucosidase
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