Epstein-Barr Virus Associated Smooth-Muscle Tumor of the Central Nervous System

Neurographics ◽  
2017 ◽  
Vol 7 (4) ◽  
pp. 288-290
Author(s):  
S.M. Koenig ◽  
W.B. Altmeyer ◽  
C. Bazan
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Smooth Muscle ◽  
Epstein Barr Virus ◽  
Smooth Muscle Tumor ◽  
Barr Virus ◽  
The Central Nervous System ◽  
Epstein Barr ◽  
Muscle Tumor

scholarly journals SURG-33. ROLE OF SURGERY IN TREATING EPSTEIN-BARR VIRUS-ASSOCIATED SMOOTH MUSCLE TUMOR (EBV-SMT) WITH CENTRAL NERVOUS SYSTEM INVASION: A SYSTEMIC REVIEW

2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii210-ii210
Author(s):  
Ko-Ting Chen ◽  
Ka-Wei Lau ◽  
Yu-Wei Hsu ◽  
Yin-Ting Lin
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Smooth Muscle ◽  
Epstein Barr Virus ◽  
Smooth Muscle Tumor ◽  
Systemic Review ◽  
Barr Virus ◽  
Epstein Barr ◽  
Muscle Tumor

Abstract Epstein-Barr virus-associated smooth muscle tumor (EBV-SMT) is a rare mesenchymal tumor that almost exclusively occurs in immunocompromised hosts. The term unknown malignant potential once used interchangeably to describe EBV-SMT and the less invasive clinical behavior than leiomyosarcoma indicate an indolent growth pattern of EBV-SMT. Nevertheless, an EBV-SMT with CNS invasion would result in neurological deficits which may jeopardize patients’ survival.We provide a systemic review of literature under PRISMA guideline on the clinical features, treatment modalities, role of surgery intervention and outcomes of all 65 reported EBV- SMTs with central nervous system (CNS) invasion. Over 95% of the reported cases were immunocompromised, while human immunodeficiency virus infection and post- organ transplantation being the most commonly associated underlying causes (near 90%). A 76.0% 1-year survival rate and 59.6% 5-year survival rate confirms the indolent and non-deadly nature of EBV-SMT even with CNS invasion. An immune survey and reconstruction should be conducted for every patient with CNS EBV-SMT. Surgical resection is mostly adopted as primary treatment to acquire diagnosis and relieve compressive effect. A total resection of tumor may be beneficial if tumor was symptomatic and had intracranial invasion

Epstein-Barr Virus–Associated Smooth Muscle Tumor of the Iris in a Patient With Transplant: A Case Report and Review of the Literature

2009 ◽  
Vol 133 (8) ◽  
pp. 1238-1241
Author(s):  
Le Yu ◽  
Anthony J. Aldave ◽  
Ben J. Glasgow
Keyword(s):  
Smooth Muscle ◽  
Virus Infection ◽  
Epstein Barr Virus ◽  
Smooth Muscle Tumor ◽  
Epstein Barr Virus Infection ◽  
Barr Virus ◽  
Smooth Muscle Tumors ◽  
Epstein Barr ◽  
Barr Virus Infection ◽  
Muscle Tumor

Abstract Epstein-Barr virus infection has been linked to the development of smooth muscle tumors in immunocompromised patients with organ transplants and acquired immunodeficiency syndrome. A 52-year-old female recipient of a renal transplant presented with enlarging masses of the left iris. Incisional biopsy of the mass revealed a smooth muscle tumor of the iris. Epstein-Barr virus infection was confirmed by in situ hybridization for Epstein-Barr virus–encoded, small RNA in tumor cells. Eight months after total iridectomy the patient was free of disease. Although the prognosis and classification of Epstein-Barr virus–associated smooth muscle tumors are controversial, mortalities caused by these tumors are rare.

Hepatic Cysts With an Unusual Twist: Smooth Muscle Tumor by Epstein-Barr Virus

2014 ◽  
Vol 109 ◽  
pp. S355
Author(s):  
Sricharitha Krishnamoorthy ◽  
Arup Maitra ◽  
Jennifer Bolyard ◽  
Zuoliang Xiao
Keyword(s):  
Smooth Muscle ◽  
Epstein Barr Virus ◽  
Smooth Muscle Tumor ◽  
Hepatic Cysts ◽  
Barr Virus ◽  
Epstein Barr ◽  
Muscle Tumor
Sign in / Sign up

Export Citation Format

Share Document