White Matter Alterations in Spastic Paraplegia Type 5: A Multiparametric Structural MRI Study and Correlations with Biochemical Measurements

Author(s):  
Y. Liu ◽  
Z. Ye ◽  
J. Hu ◽  
Z. Xiao ◽  
F. Zhang ◽  
...  
2021 ◽  
Vol 89 (9) ◽  
pp. S85
Author(s):  
Suheyla Cetin-Karayumak ◽  
Ofer Pasternak ◽  
Fan Zhang ◽  
Johanna Seitz ◽  
Doron Elad ◽  
...  

2016 ◽  
Vol 29 (2) ◽  
pp. 377-387 ◽  
Author(s):  
Cumhur Tas ◽  
Hazal Mogulkoc ◽  
Gul Eryilmaz ◽  
Isıl Gogcegoz-Gul ◽  
Turker Tekin Erguzel ◽  
...  

2012 ◽  
Vol 138 (3) ◽  
pp. 433-439 ◽  
Author(s):  
Burak Baykara ◽  
Neslihan Inal-Emiroglu ◽  
Nuri Karabay ◽  
Handan Çakmakçı ◽  
Nagihan Cevher ◽  
...  

2021 ◽  
Vol 13 ◽  
Author(s):  
Shuai Guan ◽  
Xiangyu Kong ◽  
Shifei Duan ◽  
Qingguo Ren ◽  
Zhaodi Huang ◽  
...  

White matter hyperintensity (WMH) is common in healthy adults in their 60s and can be seen as early as in their 30s and 40s. Alterations in the brain structural and functional profiles in adults with WMH have been repeatedly studied but with a focus on late-stage WMH. To date, structural and functional MRI profiles during the very early stage of WMH remain largely unexplored. To address this, we investigated multimodal MRI (structural, diffusion, and resting-state functional MRI) profiles of community-dwelling asymptomatic adults with very early-stage WMH relative to age-, sex-, and education-matched non-WMH controls. The comparative results showed significant age-related and age-independent changes in structural MRI-based morphometric measures and resting-state fMRI-based measures in a set of specific gray matter (GM) regions but no global white matter changes. The observed structural and functional anomalies in specific GM regions in community-dwelling asymptomatic adults with very early-stage WMH provide novel data regarding very early-stage WMH and enhance understanding of the pathogenesis of WMH.


PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e82422 ◽  
Author(s):  
Andrea Mike ◽  
Erzsebet Strammer ◽  
Mihaly Aradi ◽  
Gergely Orsi ◽  
Gabor Perlaki ◽  
...  

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