scholarly journals Persistent Blood Flow inside the Woven EndoBridge Device More Than 6 Months after Intracranial Aneurysm Treatment: Frequency, Mechanisms, and Management—A Retrospective Single-Center Study

2020 ◽  
Vol 41 (7) ◽  
pp. 1225-1231
Author(s):  
H.A. Nguyen ◽  
S. Soize ◽  
P.-F. Manceau ◽  
L. Vudang ◽  
L. Pierot
Keyword(s):  
Blood Flow ◽  
Intracranial Aneurysm ◽  
Single Center ◽  
Treatment Frequency ◽  
Aneurysm Treatment ◽  
Single Center Study ◽  
Woven Endobridge ◽  
Center Study

scholarly journals Lenvatinib-Induced Tumor-Related Hemorrhages in Patients with Large Hepatocellular Carcinomas

Oncology ◽  
2020 ◽  
pp. 1-6 ◽  
Author(s):  
Sawako Uchida-Kobayashi ◽  
Ken Kageyama ◽  
Akira Yamamoto ◽  
Hiroko Ikenaga ◽  
Kanako Yoshida ◽  
...  
Keyword(s):  
Blood Flow ◽  
Tumor Diameter ◽  
Careful Attention ◽  
Single Center ◽  
Tumor Blood Flow ◽  
Hepatocellular Carcinomas ◽  
Single Center Study ◽  
Life Threatening ◽  
Maximum Tumor Diameter ◽  
Center Study

<b><i>Introduction:</i></b> Lenvatinib has been approved as a systemic therapy for patients with unresectable hepatocellular carcinoma (HCC). We recently experienced lenvatinib-induced tumor-related hemorrhage in patients with HCC. The full details of tumor-related hemorrhage as a lenvatinib-related adverse event have not been elucidated. <b><i>Methods:</i></b> This was a retrospective single-center study that enrolled consecutive patients treated with lenvatinib for unresectable HCC from April 2018 to February 2020. <b><i>Results:</i></b> Sixty-eight consecutive patients were enrolled in this study. Among them, 5 cases developed intraperitoneal or intratumoral hemorrhages. The patients with hemorrhage had larger tumors (maximum tumor size, 97.5 ± 46.4 and 38.2 ± 28.8 mm, respectively; <i>p</i> = 0.009) than the patients without hemorrhage. The dosing period of lenvatinib (median, 3 and 93 days, respectively; <i>p</i> &#x3c; 0.001) and the survival time from initial administration of lenvatinib (median, 77 and 495 days, respectively; <i>p</i> &#x3c; 0.001) of the patients with hemorrhage were shorter than those of the patients without hemorrhage. Especially, in 4 cases with large HCCs (maximum tumor diameter was &#x3e;90 mm), tumor hemorrhage with vascular lake-like phenomenon was evident, although most tumor blood flow was suppressed. <b><i>Discussion/Conclusion:</i></b> It becomes clear that lenvatinib treatment brings about tumor-related hemorrhages despite rapid suppression of tumor blood flow. We speculate that lenvatinib quickly blocks the feeding circulation, resulting in tumor hemorrhage by necrosis. Clinicians should pay careful attention to the development of life-threatening hemorrhages when treating large HCCs with lenvatinib.

1655: Long-Term Functional Outcome in Orthotopic Bladder Replacement in Women: A Single Center Study

2007 ◽  
Vol 177 (4S) ◽  
pp. 549-549
Author(s):  
Hannes Steiner ◽  
Thomas Akkad ◽  
Christian Gozzi ◽  
Brigitte Springer-Stoehr ◽  
Georg Bartsch
Keyword(s):  
Functional Outcome ◽  
Single Center ◽  
Bladder Replacement ◽  
Single Center Study ◽  
Center Study

ENDOSCOPIC TREATMENT OF RECTAL NEUROENDOCRINE TUMORS IN A 12 YEAR RETROSPECTIVE SINGLE CENTER STUDY

2019 ◽  
Author(s):  
K Dąbkowski ◽  
A Białek ◽  
N Rusiniak-Rossińska ◽  
K Michalska ◽  
B Kos-Kudła ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Endoscopic Treatment ◽  
Single Center ◽  
Single Center Study ◽  
Center Study

A Retrospective Single-center Study on Time Critical Neurological Disorders in the Emergency Room of a Tertiary Pediatric Center

2019 ◽  
Author(s):  
Michaela Bonfert ◽  
Claire Andonian ◽  
Christoph Bidlingmaier ◽  
Claudia Berlin ◽  
Ingo Borggraefe ◽  
...  
Keyword(s):  
Emergency Room ◽  
Neurological Disorders ◽  
Single Center ◽  
Single Center Study ◽  
Time Critical ◽  
Pediatric Center ◽  
Center Study

Aortic Root Replacement for Destructive Endocarditis—Microbiological Considerations: A Single-Center Study

2020 ◽  
Author(s):  
M. Szczechowicz ◽  
S. Mkalaluh ◽  
A. Mashhour ◽  
K. Zhigalov ◽  
A. Weymann ◽  
...  
Keyword(s):  
Aortic Root ◽  
Aortic Root Replacement ◽  
Single Center ◽  
Single Center Study ◽  
Center Study
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