scholarly journals Incidental Brain MRI Findings in Children: A Systematic Review and Meta-Analysis

2019 ◽  
Author(s):  
V. Dangouloff-Ros ◽  
C.-J. Roux ◽  
G. Boulouis ◽  
R. Levy ◽  
N. Nicolas ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Brain Mri ◽  
Mri Findings

scholarly journals Brain MRI findings in COVID-19 patients with PRES: A systematic review

2021 ◽  
Author(s):  
Rubaya Yeahia ◽  
Javin Schefflein ◽  
Patrick Chiarolanzio ◽  
Anna Rozenstein ◽  
William Gomes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Brain Mri ◽  
Mri Findings

scholarly journals MRI Findings of Disc Degeneration are More Prevalent in Adults with Low Back Pain than in Asymptomatic Controls: A Systematic Review and Meta-Analysis

2015 ◽  
Vol 36 (12) ◽  
pp. 2394-2399 ◽  
Author(s):  
W. Brinjikji ◽  
F.E. Diehn ◽  
J.G. Jarvik ◽  
C.M. Carr ◽  
D.F. Kallmes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Low Back Pain ◽  
Back Pain ◽  
Disc Degeneration ◽  
Meta Analysis ◽  
Low Back ◽  
Mri Findings

Hypothalamic-Bulbar MRI Hyperintensity in Anti-IgLON5 Disease with Serum-Restricted Antibodies: A Case Report and Systematic Review of Literature

2020 ◽  
pp. 1-9
Author(s):  
Matteo Tagliapietra ◽  
Emma Frasson ◽  
Davide Cardellini ◽  
Sara Mariotto ◽  
Sergio Ferrari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sleep Disorders ◽  
Movement Disorders ◽  
English Literature ◽  
Brain Mri ◽  
Variable Response ◽  
Mri Findings ◽  
Comprehensive Overview ◽  
Presenting Symptoms ◽  
Vocal Cord Paresis

Background: Anti-IgLON5 disease is a rare neurodegenerative tauopathy that displays heterogeneity in clinical spectrum, disease course, cerebrospinal fluid (CSF) findings, and variable response to immunotherapy. Sleep disorders, bulbar dysfunction, and gait abnormalities are common presenting symptoms, and conventional brain MRI scanning is often unrevealing. Objective: To provide a comprehensive overview of the literature and to assess the frequency of symptoms, MRI findings, and treatment response in patients with IgLON5 autoimmunity in the serum and CSF or restricted to serum. Methods: We examined a 65-year-old woman with bulbar-onset IgLON5 disease with serum-restricted antibodies, and we also performed a systematic review of all confirmed cases reported in the English literature. Results: We identified 93 patients, included our case. Clinical data were obtained in 58 subjects, in whom the most frequent symptoms were sleep-disordered breathing, dysphagia, parasomnias, dysarthria, limb or gait ataxia, stridor or vocal cord paresis, movement disorders, and postural instability. Distinct MRI alterations were identified in 12.5% of cases, as opposed to unspecific or unremarkable changes in the remaining patients. T2-hyperintense non-enhancing signal alterations involving the hypothalamus and the brainstem tegmentum were observed only in the present case. Inflammatory CSF was found in half of the cases and serum-restricted antibodies in 4 patients. Treatment with immunosuppressant or immunomodulatory drugs led to sustained clinical response in 19/52 patients. Conclusion: Anti-IgLON5 autoimmunity should be considered in patients with sleep disorders, bulbar syndrome, autonomic involvement, and movement disorders, and high-field brain MRI can be of diagnostic help.

A systematic review of brain MRI findings in monogenic disorders strongly associated with autism spectrum disorder

2021 ◽  
Author(s):  
Veronica Frewer ◽  
Courtney P. Gilchrist ◽  
Simonne E. Collins ◽  
Katrina Williams ◽  
Marc L. Seal ◽  
...  
Keyword(s):  
Systematic Review ◽  
Autism Spectrum Disorder ◽  
Brain Mri ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Mri Findings ◽  
Monogenic Disorders

scholarly journals Meningioma MRI radiomics and machine learning: systematic review, quality score assessment, and meta-analysis

2021 ◽  
Author(s):  
Lorenzo Ugga ◽  
Teresa Perillo ◽  
Renato Cuocolo ◽  
Arnaldo Stanzione ◽  
Valeria Romeo ◽  
...  
Keyword(s):  
Machine Learning ◽  
Systematic Review ◽  
Methodological Quality ◽  
Meta Analysis ◽  
Preoperative Evaluation ◽  
Brain Mri ◽  
Quality Score ◽  
Intracranial Meningioma ◽  
Machine Learning Applications ◽  
Year 2000

Abstract Purpose To systematically review and evaluate the methodological quality of studies using radiomics for diagnostic and predictive purposes in patients with intracranial meningioma. To perform a meta-analysis of machine learning studies for the prediction of intracranial meningioma grading from pre-operative brain MRI. Methods Articles published from the year 2000 on radiomics and machine learning applications in brain imaging of meningioma patients were included. Their methodological quality was assessed by three readers with the radiomics quality score, using the intra-class correlation coefficient (ICC) to evaluate inter-reader reproducibility. A meta-analysis of machine learning studies for the preoperative evaluation of meningioma grading was performed and their risk of bias was assessed with the Quality Assessment of Diagnostic Accuracy Studies tool. Results In all, 23 studies were included in the systematic review, 8 of which were suitable for the meta-analysis. Total (possible range, −8 to 36) and percentage radiomics quality scores were respectively 6.96 ± 4.86 and 19 ± 13% with a moderate to good inter-reader reproducibility (ICC = 0.75, 95% confidence intervals, 95%CI = 0.54–0.88). The meta-analysis showed an overall AUC of 0.88 (95%CI = 0.84–0.93) with a standard error of 0.02. Conclusions Machine learning and radiomics have been proposed for multiple applications in the imaging of meningiomas, with promising results for preoperative lesion grading. However, future studies with adequate standardization and higher methodological quality are required prior to their introduction in clinical practice.

scholarly journals Clinical prognosis of FLAIR hyperintense arteries in ischaemic stroke patients: a systematic review and meta-analysis

2020 ◽  
Vol 91 (5) ◽  
pp. 475-482
Author(s):  
Zien Zhou ◽  
Alejandra Malavera ◽  
Sohei Yoshimura ◽  
Candice Delcourt ◽  
Grant Mair ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ischaemic Stroke ◽  
Functional Outcome ◽  
Endovascular Therapy ◽  
Meta Analysis ◽  
Brain Mri ◽  
Cochrane Central Register ◽  
Clinical Prognosis ◽  
Increased Risk ◽  
Fluid Attenuated Inversion Recovery

ObjectiveWe performed a systematic review and meta-analysis to determine the association of fluid-attenuated inversion recovery (FLAIR) hyperintense arteries (FLAIR-HAs) on brain MRI and prognosis after acute ischaemic stroke (AIS).MethodsWe searched Medline, Embase and Cochrane Central Register of Controlled Trials for studies reporting clinical or imaging outcomes with presence of FLAIR-HAs after AIS. Two researchers independently assessed eligibility of retrieved studies and extracted data, including from the Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED). Outcomes were unfavourable functional outcome (primary, modified Rankin scale scores 3–6 or 2–6), death, intermediate clinical and imaging outcomes. We performed subgroup analyses by treatment or types of FLAIR-HAs defined by location (at proximal/distal middle cerebral artery (MCA), within/beyond diffusion-weighted imaging (DWI) lesion) or extent.ResultsWe included 36 cohort studies (33 prospectively collected) involving 3577 patients. FLAIR-HAs were not associated with functional outcome overall (pooled risk ratio 0.87, 95% CI 0.71 to 1.06), but were significantly associated with better outcome in those receiving endovascular therapy (0.56, 95% CI 0.41 to 0.75). Contrary to FLAIR-HAs at proximal MCA or within DWI lesions, FLAIR-HAs beyond DWI lesions were associated with better outcome (0.67, 95% CI 0.57 to 0.79). FLAIR-HAs favoured recanalisation (1.21, 95% CI 1.06 to 1.38) with increased risk of intracerebral haemorrhage (2.07, 95% CI 1.37 to 3.13) and early neurological deterioration (1.93, 95% CI 1.30 to 2.85).ConclusionsFLAIR-HAs were not associated with functional outcome overall but were associated with outcome after endovascular therapy for AIS. FLAIR-HAs were also associated with early recanalisation or haemorrhagic complications, and early neurologic deterioration.PROSPERO registration numberCRD42019131168.

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