scholarly journals Underdevelopment of the Human Hippocampus in Callosal Agenesis: An In Vivo Fetal MRI Study

2019 ◽  
Author(s):  
V. Knezović ◽  
G. Kasprian ◽  
A. Štajduhar ◽  
E. Schwartz ◽  
M. Weber ◽  
...  
Keyword(s):  
Fetal Mri ◽  
Callosal Agenesis ◽  
Human Hippocampus ◽  
Mri Study

scholarly journals Normal human brainstem development in vivo: a quantitative fetal MRI study

2020 ◽  
Author(s):  
G. O. Dovjak ◽  
V. Schmidbauer ◽  
P. C. Brugger ◽  
G. M. Gruber ◽  
M. Diogo ◽  
...  
Keyword(s):  
Fetal Mri ◽  
Normal Human ◽  
Mri Study

The human hippocampus at 7 T-In vivo MRI

Hippocampus ◽  
2009 ◽  
Vol 19 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Jens M. Theysohn ◽  
O. Kraff ◽  
S. Maderwald ◽  
M.U. Schlamann ◽  
A. de Greiff ◽  
...  
Keyword(s):  
Human Hippocampus

scholarly journals Assessment of Albumin ECM Accumulation and Inflammation as Novel In Vivo Diagnostic Targets for Multi-Target MR Imaging

Biology ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 964
Author(s):  
Jana Möckel ◽  
Julia Brangsch ◽  
Carolin Reimann ◽  
Jan O. Kaufmann ◽  
Ingolf Sack ◽  
...  
Keyword(s):  
Inductively Coupled Plasma ◽  
Endothelial Damage ◽  
Plaque Burden ◽  
Signal Loss ◽  
Inductively Coupled ◽  
Before And After ◽  
Plasma Mass Spectrometry ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Study

Atherosclerosis is a progressive inflammatory vascular disease characterized by endothelial dysfunction and plaque burden. Extracellular matrix (ECM)-associated plasma proteins play an important role in disease development. Our magnetic resonance imaging (MRI) study investigates the feasibility of using two different molecular MRI probes for the simultaneous assessment of ECM-associated intraplaque albumin deposits caused by endothelial damage and progressive inflammation in atherosclerosis. Male apolipoprotein E-deficient (ApoE-/-)-mice were fed a high-fat diet (HFD) for 2 or 4 months. Another ApoE-/--group was treated with pravastatin and received a HFD for 4 months. T1- and T2*-weighted MRI was performed before and after albumin-specific MRI probe (gadofosveset) administration and a macrophage-specific contrast agent (ferumoxytol). Thereafter, laser ablation inductively coupled plasma mass spectrometry and histology were performed. With advancing atherosclerosis, albumin-based MRI signal enhancement and ferumoxytol-induced signal loss areas in T2*-weighted MRI increased. Significant correlations between contrast-to-noise-ratio (CNR) post-gadofosveset and albumin stain (R2 = 0.78, p < 0.05), and signal loss areas in T2*-weighted MRI with Perls’ Prussian blue stain (R2 = 0.83, p < 0.05) were observed. No interference of ferumoxytol with gadofosveset enhancement was detectable. Pravastatin led to decreased inflammation and intraplaque albumin. Multi-target MRI combining ferumoxytol and gadofosveset is a promising method to improve diagnosis and treatment monitoring in atherosclerosis.

scholarly journals Handedness in monkeys reflects hemispheric specialization within the central sulcus. An in vivo MRI study in right- and left-handed olive baboons

Cortex ◽  
2019 ◽  
Vol 118 ◽  
pp. 203-211 ◽  
Author(s):  
Konstantina Margiotoudi ◽  
Damien Marie ◽  
Nicolas Claidière ◽  
Olivier Coulon ◽  
Muriel Roth ◽  
...  
Keyword(s):  
Hemispheric Specialization ◽  
Central Sulcus ◽  
Olive Baboons ◽  
Left Handed ◽  
Mri Study

A new method for the in vivo volumetric measurement of the human hippocampus with high neuroanatomical accuracy

Hippocampus ◽  
2000 ◽  
Vol 10 (6) ◽  
pp. 752-758 ◽  
Author(s):  
J. Pantel ◽  
D. S. O'Leary ◽  
K. Cretsinger ◽  
H. J. Bockholt ◽  
H. Keefe ◽  
...  
Keyword(s):  
New Method ◽  
Volumetric Measurement ◽  
Human Hippocampus

Brain anatomy and ageing in non-demented adults with Down's syndrome: an in vivo MRI study

2009 ◽  
Vol 40 (4) ◽  
pp. 611-619 ◽  
Author(s):  
F. Beacher ◽  
E. Daly ◽  
A. Simmons ◽  
V. Prasher ◽  
R. Morris ◽  
...  
Keyword(s):  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Brain Regions ◽  
Accelerated Ageing ◽  
Brain Anatomy ◽  
Parietal Lobes ◽  
Age Related ◽  
Brain Ageing ◽  
Mri Study

BackgroundPeople with Down's syndrome (DS) are at high risk for developing dementia in middle age. The biological basis for this is unknown. It has been proposed that non-demented adults with DS may undergo accelerated brain ageing.MethodWe used volumetric magnetic resonance imaging (MRI) and manual tracing to compare brain anatomy and ageing in 39 non-demented adults with DS and 42 healthy controls.ResultsIndividuals with DS had significant differences in brain anatomy. Furthermore, individuals with DS had a significantly greater age-related reduction in volume of frontal, temporal and parietal lobes, and a significantly greater age-related increase in volume of peripheral cerebrospinal fluid (CSF).ConclusionsNon-demented adults with DS have differences in brain anatomy and ‘accelerated’ ageing of some brain regions. This may increase their risk for age-related cognitive decline and Alzheimer's disease (AD).

scholarly journals Ultra-high resolution in-vivo 7.0 T structural imaging of the human hippocampus reveals the endfolial pathway

NeuroImage ◽  
2015 ◽  
Vol 112 ◽  
pp. 1-6 ◽  
Author(s):  
Mansi B. Parekh ◽  
Brian K. Rutt ◽  
Ryan Purcell ◽  
Yuanxin Chen ◽  
Michael M. Zeineh
Keyword(s):  
High Resolution ◽  
Structural Imaging ◽  
Human Hippocampus

scholarly journals High-resolution 7T MRI of the human hippocampus in vivo

2008 ◽  
Vol 28 (5) ◽  
pp. 1266-1272 ◽  
Author(s):  
Bradley P. Thomas ◽  
E. Brian Welch ◽  
Blake D. Niederhauser ◽  
William O. Whetsell ◽  
Adam W. Anderson ◽  
...  
Keyword(s):  
High Resolution ◽  
Human Hippocampus
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