scholarly journals Radiologic-Pathologic Correlation of Tumor Thickness and Its Prognostic Importance in Squamous Cell Carcinoma of the Oral Cavity: Implications for the Eighth Edition Tumor, Node, Metastasis Classification

2018 ◽  
Vol 39 (10) ◽  
pp. 1896-1902 ◽  
Author(s):  
E.A.M. Weimar ◽  
S.H. Huang ◽  
L. Lu ◽  
B. O'Sullivan ◽  
B. Perez-Ordonez ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tumor Thickness ◽  
Tumor Node Metastasis ◽  
Node Metastasis ◽  
Prognostic Importance ◽  
Eighth Edition ◽  
Tumor Node Metastasis Classification

scholarly journals To evaluate disparity between clinical and pathological tumor-node-metastasis staging in oral cavity squamous cell carcinoma patients and its impact on overall survival: An institutional study

2015 ◽  
Vol 04 (04) ◽  
pp. 183-185 ◽  
Author(s):  
Karan Gupta ◽  
Naresh K Panda ◽  
Jaimanti Bakshi ◽  
Ashim Das
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Tnm Staging ◽  
Advanced Stage ◽  
Tumor Node Metastasis ◽  
Node Metastasis ◽  
N Stage

Abstract Background: Accurate clinical staging is important for patient counseling, treatment planning, prognostication, and rational design of clinical trials. In head and neck squamous cell carcinoma, discrepancy between clinical and pathological staging has been reported. Objective: To evaluate any disparity between clinical and pathological tumor-node-metastasis (TNM) staging in oral cavity squamous cell carcinoma (OCSCC) patients and any impact of the same on survival. Materials and Methods: Retrospective chart review from year 2007 to 2013, at a tertiary care center. Statistical Analysis: All survival analyses were performed using SPSS for Windows version 15 (Chicago, IL, USA). Disease-free survival curves were generated using Kaplan-Meier algorithm. Results: One hundred and twenty-seven patients with OCSCC were analyzed. Seventy-nine (62.2%) were males and 48 (37.8%) females with a mean age at presentation 43.6 years (29-79 years). The highest congruence between clinical and pathological T-staging seen for clinical stage T1 and T4 at 76.9% and 73.4% with pathological T-stage. Similarly, the highest congruence between clinical and pathological N-stage seen for clinical N0 and N3 at 86.4% and 91.7% with pathological N-stage. Of clinically early stage patients, 67.5% remained early stage, and 32.5% were upstaged to advanced stage following pathological analysis. Of the clinically advanced stage patients, 75% remained advanced, and 25% were pathologically downstaged. This staging discrepancy did not significantly alter the survival. Conclusion: Some disparity exists in clinical and pathological TNM staging of OCSCC, which could affect treatment planning and survival of patients. Hence, more unified and even system of staging for the disease is required for proper decision-making.

Association of CCL2 with Lymph Node Metastasis and Macrophage Infiltration in Oral Cavity and Lip Squamous Cell Carcinoma

Tumor Biology ◽  
2008 ◽  
Vol 29 (2) ◽  
pp. 114-121 ◽  
Author(s):  
Fernanda Oliveira Ferreira ◽  
Fernanda Luiza Leite Ribeiro ◽  
Aline Carvalho Batista ◽  
Cláudio Rodrigues Leles ◽  
Rita de Cassia Goncalves Alencar ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Macrophage Infiltration ◽  
Node Metastasis

scholarly journals Predictive value of tumor thickness for cervical lymph-node involvement in squamous cell carcinoma of the oral cavity

Cancer ◽  
2009 ◽  
Vol 115 (7) ◽  
pp. 1489-1497 ◽  
Author(s):  
Shao Hui Huang ◽  
David Hwang ◽  
Gina Lockwood ◽  
David P. Goldstein ◽  
Brian O'Sullivan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Predictive Value ◽  
Cervical Lymph Node ◽  
Lymph Node Involvement ◽  
Tumor Thickness ◽  
Node Involvement
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