scholarly journals Comparison of Sagittal FSE T2, STIR, and T1-Weighted Phase-Sensitive Inversion Recovery in the Detection of Spinal Cord Lesions in MS at 3T

2016 ◽  
Vol 37 (5) ◽  
pp. 970-975 ◽  
Author(s):  
P. Alcaide-Leon ◽  
A. Pauranik ◽  
L. Alshafai ◽  
S. Rawal ◽  
J. Oh ◽  
...  
PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0247813
Author(s):  
Adrien Goujon ◽  
Sonia Mirafzal ◽  
Kevin Zuber ◽  
Romain Deschamps ◽  
Jean-Claude Sadik ◽  
...  

Background and purpose To compare 3D-Fast Gray Matter Acquisition with Phase Sensitive Inversion Recovery (3D-FGAPSIR) with conventional 3D-Short-Tau Inversion Recovery (3D-STIR) and sagittal T1-and T2-weighted MRI dataset at 3 Tesla when detecting MS spinal cord lesions. Material and methods This prospective single-center study was approved by an institutional review board and enrolled participants from December 2016 to August 2018. Two neuroradiologists blinded to all data, individually analyzed the 3D-FGAPSIR and the conventional datasets separately and in random order. Discrepancies were resolved by consensus by a third neuroradiologist. The primary judgment criterion was the number of MS spinal cord lesions. Secondary judgment criteria included lesion enhancement, lesion delineation, reader-reported confidence and lesion-to-cord-contrast-ratio. A Wilcoxon’s test was used to compare the two datasets. Results 51 participants were included. 3D-FGAPSIR detected significantly more lesions than the conventional dataset (344 versus 171 respectively, p<0.001). Two participants had no detected lesion on the conventional dataset, whereas 3D-FGAPSIR detected at least one lesion. 3/51 participants had a single enhancing lesion detected by both datasets. Lesion delineation and reader-reported confidence were significantly higher with 3D-FGAPSIR: 4.5 (IQR 1) versus 2 (IQR 0.5), p<0.0001 and 4.5 (IQR 1) versus 2.5 (IQR 0.5), p<0.0001. Lesion-to-cord-contrast-ratio was significantly higher using 3D-FGAPSIR as opposed to 3D-STIR and T2: 1.4 (IQR 0,3) versus 0.4 (IQR 0,1) and 0.3 (IQR 0,1)(p = 0.04). Correlations with clinical data and inter- and intra-observer agreements were higher with 3D-FGAPSIR. Conclusion 3D-FGAPSIR improved overall MS spinal cord lesion detection as compared to conventional set and detected all enhancing lesions.


PLoS ONE ◽  
2018 ◽  
Vol 13 (11) ◽  
pp. e0208255 ◽  
Author(s):  
Nicholas T. Olney ◽  
Antje Bischof ◽  
Howard Rosen ◽  
Eduardo Caverzasi ◽  
William A. Stern ◽  
...  

Radiology ◽  
2008 ◽  
Vol 246 (1) ◽  
pp. 258-264 ◽  
Author(s):  
Aziz H. Poonawalla ◽  
Ping Hou ◽  
Flavia A. Nelson ◽  
Jerry S. Wolinsky ◽  
Ponnada A. Narayana

2017 ◽  
Vol 59 (8) ◽  
pp. 819-827 ◽  
Author(s):  
V. Panara ◽  
R Navarra ◽  
P. A. Mattei ◽  
E. Piccirilli ◽  
A. R. Cotroneo ◽  
...  

2004 ◽  
Vol 51 (2) ◽  
pp. 408-412 ◽  
Author(s):  
Peter Kellman ◽  
Christopher K. Dyke ◽  
Anthony H. Aletras ◽  
Elliot R. McVeigh ◽  
Andrew E. Arai

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