scholarly journals Detection of Calcifications in Retinoblastoma Using Gradient-Echo MR Imaging Sequences: Comparative Study between In Vivo MR Imaging and Ex Vivo High-Resolution CT

2014 ◽  
Vol 36 (2) ◽  
pp. 355-360 ◽  
Author(s):  
F. Rodjan ◽  
P. de Graaf ◽  
P. van der Valk ◽  
T. Hadjistilianou ◽  
A. Cerase ◽  
...  
2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Hirofumi Fujii ◽  
Masayuki Yamaguchi ◽  
Kazumasa Inoue ◽  
Yasuko Mutou ◽  
Masashi Ueda ◽  
...  

Purpose. We aimed to clearly visualize heterogeneous distribution of hypoxia-inducible factor 1α(HIF) activity in tumor tissuesin vivo.Methods. We synthesized of125I-IPOS, a125I labeled chimeric protein probe, that would visualize HIF activity. The biodistribution of125I-IPOS in FM3A tumor-bearing mice was evaluated. Then, the intratumoral localization of this probe was observed by autoradiography, and it was compared with histopathological findings. The distribution of125I-IPOS in tumors was imaged by a small animal SPECT/CT scanner. The obtainedin vivoSPECT-CT fusion images were compared withex vivoimages of excised tumors. Fusion imaging with MRI was also examined.Results.125I-IPOS well accumulated in FM3A tumors. The intratumoral distribution of125I-IPOS by autoradiography was quite heterogeneous, and it partially overlapped with that of pimonidazole. High-resolution SPECT-CT fusion images successfully demonstrated the heterogeneity of125I-IPOS distribution inside tumors. SPECT-MRI fusion images could give more detailed information about the intratumoral distribution of125I-IPOS.Conclusion. High-resolution SPECT images successfully demonstrated heterogeneous intratumoral distribution of125I-IPOS. SPECT-CT fusion images, more favorably SPECT-MRI fusion images, would be useful to understand the features of heterogeneous intratumoral expression of HIF activityin vivo.


2013 ◽  
Vol 82 (2) ◽  
pp. 264-269 ◽  
Author(s):  
Matthias Dettmer ◽  
Nicola Glaser-Gallion ◽  
Paul Stolzmann ◽  
Florian Glaser-Gallion ◽  
Juergen Fornaro ◽  
...  

2020 ◽  
Vol 7 (02) ◽  
pp. 1
Author(s):  
Hirohisa Oda ◽  
Holger R. Roth ◽  
Takaaki Sugino ◽  
Naoki Sunaguchi ◽  
Noriko Usami ◽  
...  

Radiology ◽  
1990 ◽  
Vol 176 (2) ◽  
pp. 457-460 ◽  
Author(s):  
J Bittoun ◽  
H Saint-Jalmes ◽  
B G Querleux ◽  
L Darrasse ◽  
O Jolivet ◽  
...  

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Fabian Preisner ◽  
Birgit Friedmann-Bette ◽  
Michaela Wehrstein ◽  
Dominik F Vollherbst ◽  
Sabine Heiland ◽  
...  

1992 ◽  
Vol 77 (Supplement) ◽  
pp. A1239
Author(s):  
R. H. Brown ◽  
S. Wood ◽  
E. Zerhouni ◽  
E. A. Hoffman ◽  
W. Mitzner ◽  
...  

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