scholarly journals Corticospinal Tract MR Signal-Intensity Pseudonormalization on Magnetization Transfer Contrast Imaging: A Potential Pitfall in the Interpretation of the Advanced Compromise of Upper Motor Neurons in Amyotrophic Lateral Sclerosis

2012 ◽  
Vol 33 (5) ◽  
pp. E79-E80 ◽  
Author(s):  
A.J. da Rocha ◽  
A.C. Martins Maia ◽  
B.C. Oliveira Valério
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Motor Neurons ◽  
Signal Intensity ◽  
Corticospinal Tract ◽  
Magnetization Transfer ◽  
Contrast Imaging ◽  
Magnetization Transfer Contrast ◽  
Magnetization Transfer Contrast Imaging ◽  
Upper Motor Neurons ◽  
Lateral Sclerosis

scholarly journals Magnetic resonance findings in amyotrophic lateral sclerosis using a spin echo magnetization transfer sequence: preliminary report

1999 ◽  
Vol 57 (4) ◽  
pp. 912-915 ◽  
Author(s):  
ANTÔNIO JOSÉ DA ROCHA ◽  
ANTONIO CARLOS MARTINS MAIA JUNIOR ◽  
ROBERTO GOMES NOGUEIRA ◽  
HENRIQUE MANOEL LEDERMAN
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Magnetic Resonance ◽  
Preliminary Report ◽  
Corticospinal Tract ◽  
Spin Echo ◽  
Magnetization Transfer ◽  
Control Group ◽  
Spin Echo Sequence ◽  
Lateral Sclerosis

We present the magnetic resonance (MR) findings of five patients with amyotrophic lateral sclerosis (ALS) using a spin-echo sequence with an additional magnetization transfer (MT) pulse on T1-weighted images (T1 SE/MT). These findings were absent in the control group and consisted of hyperintensity of the corticospinal tract. Moreover we discuss the principles and the use of this fast but simple MR technique in the diagnosis of ALS

scholarly journals Magnetization transfer contrast imaging of hepatic neoplasms

1994 ◽  
Vol 12 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Michael D. Hollett ◽  
Alex M. Aisen ◽  
Hong N. Yeung ◽  
Isaac R. Francis ◽  
Robert L. Bree
Keyword(s):  
Magnetization Transfer ◽  
Contrast Imaging ◽  
Magnetization Transfer Contrast ◽  
Hepatic Neoplasms ◽  
Magnetization Transfer Contrast Imaging

Motor neuron disease

2018 ◽  
Author(s):  
Martin R. Turner
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Motor Neurons ◽  
Corticospinal Tract ◽  
Muscular Atrophy ◽  
Muscle Denervation ◽  
Genetic Overlap ◽  
Upper Motor Neurons ◽  
Primary Lateral ◽  
Lateral Sclerosis

Motor neuron disease (MND) is characterized by progressive muscular weakness due to simultaneous degeneration of lower and upper motor neurons (L/UMNs). Involvement of LMNs, arising from the anterior horns of the spinal cord and brainstem, leads to secondary wasting as a result of muscle denervation. Involvement of the UMNs of the motor cortex and corticospinal tract results in spasticity. In ~85% of cases, there is clear clinical involvement of both, and the condition is termed ‘amyotrophic lateral sclerosis’ (ALS; a term often used synonymously with MND). In ~13% of cases, there may be only LMN signs apparent, in which case the condition is termed ‘progressive muscular atrophy’, although such cases have a natural history that is to largely identical to that of ALS. In a very small group of patients (~2%), there are only UMN signs for at least the first 4 years, in which case the condition is termed ‘primary lateral sclerosis’; such cases have a uniformly slower progression. There is clinical, neuropathological, and genetic overlap between MND and some forms of frontotemporal dementia.

scholarly journals Whole-body magnetization transfer contrast imaging

2006 ◽  
Vol 24 (5) ◽  
pp. 1183-1187 ◽  
Author(s):  
Andreas Boss ◽  
Petros Martirosian ◽  
Klaus Küper ◽  
Gerhard Fierlbeck ◽  
Claus D. Claussen ◽  
...  
Keyword(s):  
Magnetization Transfer ◽  
Whole Body ◽  
Contrast Imaging ◽  
Magnetization Transfer Contrast ◽  
Magnetization Transfer Contrast Imaging

Systematic Variation of Off-Resonance Prepulses for Clinical Magnetization Transfer Contrast Imaging at 0.2, 1.5, and 3.0 Tesla

2008 ◽  
Vol 43 (1) ◽  
pp. 16-26 ◽  
Author(s):  
Petros Martirosian ◽  
Andreas Boss ◽  
Michael Deimling ◽  
Berthold Kiefer ◽  
Christina Schraml ◽  
...  
Keyword(s):  
Magnetization Transfer ◽  
Systematic Variation ◽  
Contrast Imaging ◽  
3.0 Tesla ◽  
Magnetization Transfer Contrast ◽  
Magnetization Transfer Contrast Imaging
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