scholarly journals Tapering of the Cervical Spinal Canal in Patients with Chiari I Malformations

2012 ◽  
Vol 33 (7) ◽  
pp. 1326-1330 ◽  
Author(s):  
M. Hirano ◽  
V. Haughton ◽  
A. Munoz del Rio
2015 ◽  
Vol 37 (4) ◽  
pp. 755-758 ◽  
Author(s):  
A. Thompson ◽  
N. Madan ◽  
J.R. Hesselink ◽  
G. Weinstein ◽  
A. Munoz del Rio ◽  
...  

2012 ◽  
Vol 33 (9) ◽  
pp. 1752-1755 ◽  
Author(s):  
J. Hammersley ◽  
V. Haughton ◽  
Y. Wang ◽  
A. Munoz del Rio

2011 ◽  
Vol 32 (6) ◽  
pp. 1149-1153 ◽  
Author(s):  
S. Shah ◽  
V. Haughton ◽  
A. Muñoz del Río

2013 ◽  
Vol 26 (1) ◽  
pp. 106-110 ◽  
Author(s):  
K-A. Mardal ◽  
G. Rutkowska ◽  
S. Linge ◽  
V. Haughton

Chiari I patients have increased CSF velocities in the foramen magnum due hypothetically to increased pressure gradients or reduced flow resistance. We calculated flow resistance in the cervical spinal canal in a group of subjects with and without the Chiari malformation. Eight subjects including healthy volunteers and Chiari I patients were studied. From 3D high resolution MR images of the cervical spine mathematical models of the subarachnoid spaces were created by means of standard programs for segmentation and discretization. Oscillatory flow through the subarachnoid space was simulated. Cross-sectional area of the subarachnoid space was computed at each level from C1 through C4 and the length of this spinal canal segment was measured. Peak caudad CSF flow velocity at each level was plotted against cross-section area. CSF volumetric flux and resistance were calculated for each subject. The correlation between velocity and resistance was calculated. In all subjects, peak velocities increased progressively from C1 to C4 by 0.6 to 0.7 cm/s per level. Spinal canal areas diminished from C1 to C5 in each subject at a rate of 0.25 to 0.29 cm2per level. Resistance averaged 4.3 pascal/ml/s in the eight subjects; 3.8 pascal/ml/s in patients with tonsilar herniation and 6.0 pascal/ml/s in volunteers. Velocity correlated inversely with resistance (R2= 0.6). CSF velocities correlated inversely with the flow resistance in the upper cervical spinal canal. Resistance tends to be lower in Chiari I patients than in healthy volunteers.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Minghao Shao ◽  
Jun Yin ◽  
Feizhou Lu ◽  
Chaojun Zheng ◽  
Hongli Wang ◽  
...  

Objective.To evaluate the forward shifting of cervical spinal cords in different segments of patients with Hirayama disease to determine whether the disease is self-limiting.Methods.This study was performed on 11 healthy subjects and 64 patients. According to the duration, the patients were divided into 5 groups (≤1 year, 1-2 years, 2-3 years, 3-4 years, and ≥4 years). Cervical magnetic resonance imaging (MRI) of flexion and conventional position was performed. The distances between the posterior edge of the spinal cord and the cervical spinal canal (X), the anterior and posterior wall of the cervical spinal canal (Y), and the anterior-posterior (A) and the transverse diameter (B) of spinal cord cross sections were measured at different cervical spinal segments (C4 to T1).Results.In cervical flexion position, a significant increase inX/Yof C4-5 segments was found in groups 2–5, the C5-6 and C6-7 segments in groups 1–5, and the C7-T1 segments in group 5 (P<0.05). The degree of the increasedX/Yand cervical flexionX/Yof C5-6 segments were different among the 5 groups (P<0.05), which was likely due to rapid increases inX/Yduring the course of Hirayama’s disease.Conclusion.TheX/Ychange progression indicates that Hirayama disease may not be self-limiting.


2010 ◽  
Vol 15 (1) ◽  
pp. 97-103 ◽  
Author(s):  
Shin-Ichi Goto ◽  
Jutaro Umehara ◽  
Toshimi Aizawa ◽  
Shoichi Kokubun

2017 ◽  
Vol 30 (5) ◽  
pp. 405-409 ◽  
Author(s):  
Judith A Gadde ◽  
Vinil Shah ◽  
Greta B Liebo ◽  
Geir A Ringstad ◽  
I Jonathan Pomeraniec ◽  
...  

Purpose The relationship between syringomyelia and presyrinx, characterized by edema in the spinal cord, has not been firmly established. Patients with syringomyelia have abnormal spinal canal tapering that alters cerebrospinal fluid flow dynamics, but taper ratios in presyrinx have never been reported. We tested the hypothesis that presyrinx patients have abnormal spinal canal tapering. Materials and methods At six medical institutions, investigators searched the PACS system for patients with Chiari I and spinal cord edema unassociated with tumor, trauma, or other evident cause. In each case taper ratios were calculated for C1 to C4 and C4 to C7. In two age- and gender-matched control groups, Chiari I patients with no syringomyelia and patients with normal MR scans, the same measurements were made. Differences between groups were tested for statistical significance with t tests. Results The study enrolled 21 presyrinx patients and equal numbers of matched Chiari I and normal controls. C4 to C7 taper ratios were positive and steeper in presyrinx patients than in the normal controls ( p = 0.04). The upper cervical spine, C1 to C4, tapered negatively in cases and controls without significant differences between the groups. The difference in degree of tonsillar herniation was statistically significant between presyrinx patients and Chiari I controls ( p = 0.01). Conclusions Presyrinx patients have greater than normal positive tapering in the lower cervical spine and greater degree of tonsillar herniation than the controls.


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