scholarly journals Optic Nerve Sheath Diameter on MR Imaging: Establishment of Norms and Comparison of Pediatric Patients with Idiopathic Intracranial Hypertension with Healthy Controls

2011 ◽  
Vol 33 (2) ◽  
pp. 366-369 ◽  
Author(s):  
B. Shofty ◽  
L. Ben-Sira ◽  
S. Constantini ◽  
S. Freedman ◽  
A. Kesler
Keyword(s):  
Optic Nerve ◽  
Mr Imaging ◽  
Intracranial Hypertension ◽  
Idiopathic Intracranial Hypertension ◽  
Pediatric Patients ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Healthy Controls ◽  
Nerve Sheath

Neuroimaging Features of Intracranial Hypertension in Pediatric Patients With New-Onset Idiopathic Seizures, a Comparison With Patients with Confirmed Diagnosis of Idiopathic Intracranial Hypertension: A Preliminary Study

2021 ◽  
pp. 088307382110452
Author(s):  
Arash Kamali ◽  
Azin Aein ◽  
Niyousha Naderi ◽  
Sally J. Choi ◽  
Nathan Doyle ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Intracranial Hypertension ◽  
Idiopathic Intracranial Hypertension ◽  
Pediatric Patients ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Opening Pressure ◽  
Cutoff Value ◽  
Nerve Sheath ◽  
New Onset

Seizures have been reported in association with idiopathic intracranial hypertension in pediatric patients. Magnetic resonance imaging (MRI) signs of intracranial hypertension have not been investigated before in pediatric patients with new-onset idiopathic seizures. MRI scans of 182 pediatric patients were retrospectively analyzed for imaging findings of intracranial hypertension, including 46 patients with new-onset idiopathic seizures and elevated cerebrospinal fluid opening pressure, 40 patients with new-onset idiopathic seizures and normal opening pressure, 56 patients with confirmed idiopathic intracranial hypertension, and 40 age- and sex-matched controls. The optic nerve sheath diameter is significantly larger in the group with new-onset idiopathic seizures and elevated opening pressure (mean diameter of 6.02 ± 0.45 mm) compared to patients with new-onset idiopathic seizures and normal opening pressure (mean diameter of 5.24 ± 0.50 mm) ( P value <.001). The cutoff value of 6.0 mm for optic nerve sheath diameter showed 63% sensitivity and 88% specificity to differentiate pediatric patients with seizures and elevated opening pressure from those with seizures and normal opening pressure. Conclusion A cutoff value of 6.0 mm for optic nerve sheath dilation may be used as a screening imaging marker to suspect elevated opening pressure with specificity of 88% in pediatric patients with new-onset idiopathic seizures.

Sonographic assessment of the optic nerve sheath diameter in the diagnosis of idiopathic intracranial hypertension

2016 ◽  
Vol 361 ◽  
pp. 122-127 ◽  
Author(s):  
Pablo del Saz-Saucedo ◽  
Olga Redondo-González ◽  
Ángel Mateu-Mateu ◽  
Rafael Huertas-Arroyo ◽  
Rafael García-Ruiz ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Intracranial Hypertension ◽  
Idiopathic Intracranial Hypertension ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Nerve Sheath ◽  
Sonographic Assessment

Morphometric and volumetric MRI changes in idiopathic intracranial hypertension

Cephalalgia ◽  
2013 ◽  
Vol 33 (13) ◽  
pp. 1075-1084 ◽  
Author(s):  
Jan Hoffmann ◽  
Hans-Jürgen Huppertz ◽  
Christoph Schmidt ◽  
Hagen Kunte ◽  
Lutz Harms ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Mr Imaging ◽  
Pituitary Gland ◽  
Intracranial Hypertension ◽  
Idiopathic Intracranial Hypertension ◽  
Optic Nerve Sheath ◽  
Imaging Features ◽  
Imaging Findings ◽  
Nerve Sheath ◽  
Study Results

Objective We aimed at validating established imaging features of idiopathic intracranial hypertension (IIH) by using state-of-the-art MR imaging together with advanced post-processing techniques and correlated imaging findings to clinical scores. Methods Twenty-five IIH patients as well as age-, sex- and body mass index (BMI)-matched controls underwent high-resolution T1w and T2w MR imaging in a 1.5 T scanner, followed by assessment of optic nerve sheaths, pituitary gland, ventricles and Meckel's cave. Imaging findings were correlated with cerebrospinal fluid (CSF) opening pressures and clinical symptom scores of visual disturbances (visual field defects or enlarged blind spot), headache, tinnitus (pulsatile and non-pulsatile) and vertigo. CSF as well as ventricle volumes were determined by using an automated MRI volumetry algorithm. Results So-called ‘empty sella’ and optic nerve sheath distension were identified as reliable imaging signs in IIH. Posterior globe flattening turned out as a highly specific but not very sensitive sign. No abnormalities of the lateral ventricles were observed. These morphometric results could be confirmed using MR volumetry (VBM). Clinical symptoms did not correlate with an increase in lumbar opening pressure. Conclusions Our study results indicate that lateral ventricle size is not affected in IIH. In contrast, abnormalities of the pituitary gland and optic nerve sheath were reliable diagnostic signs for IIH.

Sign in / Sign up

Export Citation Format

Share Document