scholarly journals Anatomic Location and Somatotopic Arrangement of the Corticospinal Tract at the Cerebral Peduncle in the Human Brain

2011 ◽  
Vol 32 (11) ◽  
pp. 2116-2119 ◽  
Author(s):  
H.G. Kwon ◽  
J.H. Hong ◽  
S.H. Jang
Keyword(s):  
Human Brain ◽  
Corticospinal Tract ◽  
Cerebral Peduncle ◽  
Anatomic Location

Abstract WP366: Quantitative Diffusion Tensor Tractography of the Corticospinal Tract as a Predictive Outcome Parameter in Patients With Intracerebral Hemorrhage

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Bastian Volbers ◽  
Angelika Mennecke ◽  
Nicola Kästle ◽  
Hagen B Huttner ◽  
Stefan Schwab ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Corticospinal Tract ◽  
Diffusion Tensor ◽  
Clinical Status ◽  
Internal Capsule ◽  
Favorable Outcome ◽  
Outcome Variable ◽  
Cerebral Peduncle ◽  
Prognostic Impact ◽  
Posterior Limb

Introduction: Intracerebral hemorrhage (ICH) is a devastating disease with poor outcome. Established predictive markers include initial hematoma size, clinical status, intraventricular bleeding and age. However, prognostic assessment is often difficult which additionally burdens patients and caregivers and complicates rehabilitation. Functional outcome especially relies on motor function which is correlated with the integrity of the Corticospinal Tract (CST). Diffusion Tensor (DT) Tractography allows visualization of the CST. However, sufficient data about the prognostic impact of quantitative CST assessment is lacking. Methods: We prospectively enrolled patients with spontaneous supratentorial ICH admitted between 08/2012 und 08/2015. Informed consent and ethical approval was obtained. MRI scan was performed on day 5±1. DT data was normalized to MNI Space and Q-Space diffeomorphic reconstruction was performed using DSI-studio. CST was reconstructed based on quantitative anisotropy (QA) using the CST region (JHU white matter atlas) as seeding region and cerebral peduncle as region of interest (ROI). Fractional Anisotropy (FA) and QA were analyzed in the seeding and ROI region and in the posterior limb of the internal capsule (PLIC). Dichotomized modified Rankin Scale on day 90 (favorable outcome = mRS 0-2) was assessed as primary outcome variable. Results: 33 patients, mean age 70.7 y (standard deviation (SD) 12.9), 12 male, 21 with lobar hemorrhage, mean ICH volume on admission 16.5 (SD 11.3) cm 3 were included. 16 patients had a favorable outcome on day 90 (median mRS 3 (IQR 1-3.5). Mean number of reconstructed CST fiber pathways ipsilateral to ICH was higher in patients with favorable outcome (11343 (SD 8201)) than in patients with unfavorable outcome (4868 (SD 3221), p=0.008). Median QA and FA values in the PLIC ipsilateral to ICH were also higher in patients with favorable outcome (QA: 18.9 (IQR 16.2-23.3) vs. 14.6 (IQR 11.7 - 17.7), p=0.016, FA: 0.49 (IQR 0.45-0.53) vs. 0.41 (IQR 0.38-0.49), p=0.026). Conclusion: Higher FA- and QA-values in the PLIC and higher numbers of CST fiber pathways ipsilateral to ICH seem to be associated with a favorable outcome. DT Imaging may turn out as a useful quantitative predictive marker in the acute phase of ICH.

Somatotopic Arrangement of the Corticospinal Tract at the Medullary Pyramid in the Human Brain

2011 ◽  
Vol 65 (1) ◽  
pp. 46-49 ◽  
Author(s):  
Hyeok Gyu Kwon ◽  
Ji Heon Hong ◽  
Mi Young Lee ◽  
Yong Hyun Kwon ◽  
Sung Ho Jang
Keyword(s):  
Human Brain ◽  
Corticospinal Tract ◽  
Medullary Pyramid

Corticospinal Tract Location at the Upper Pons in the Human Brain

NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. S127
Author(s):  
MC Chang ◽  
SH Ahn ◽  
WM Byeon ◽  
SH Jang
Keyword(s):  
Human Brain ◽  
Corticospinal Tract

Location of the corticospinal tract at the corona radiata in human brain

2010 ◽  
Vol 1326 ◽  
pp. 75-80 ◽  
Author(s):  
Bong Soo Han ◽  
Ji Heon Hong ◽  
Cheolpyo Hong ◽  
Sang Seok Yeo ◽  
Dong hoon Lee ◽  
...  
Keyword(s):  
Human Brain ◽  
Corticospinal Tract ◽  
Corona Radiata

Identification of the anterior corticospinal tract in the human brain using diffusion tensor imaging

2011 ◽  
Vol 505 (3) ◽  
pp. 238-241 ◽  
Author(s):  
Hyeok Gyu Kwon ◽  
Dong Gyu Lee ◽  
Su Min Son ◽  
Woo Mok Byun ◽  
Cheol Pyo Hong ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Human Brain ◽  
Corticospinal Tract ◽  
Diffusion Tensor

Response to “A note on the mapping and quantification of the human brain corticospinal tract”

2014 ◽  
Vol 83 (9) ◽  
pp. 1706-1707
Author(s):  
Chao-Chun Lin ◽  
Wu-Chung Shen ◽  
Hsiao-Wen Chung
Keyword(s):  
Human Brain ◽  
Corticospinal Tract
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