scholarly journals Apparent Diffusion Coefficient Mapping for Sinonasal Diseases: Differentiation of Benign and Malignant Lesions

2011 ◽  
Vol 32 (6) ◽  
pp. 1100-1106 ◽  
Author(s):  
M. Sasaki ◽  
S. Eida ◽  
M. Sumi ◽  
T. Nakamura
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Apparent Diffusion ◽  
Malignant Lesions ◽  
Apparent Diffusion Coefficient Mapping

scholarly journals Apparent diffusion coefficient for differentiating between benign and malignant hepatic focal lesions

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Sherif Abugamra ◽  
Aya Yassin ◽  
Asmaa Saber Mostafa Abdel-Rehim ◽  
Dina Sayed Sheha
Keyword(s):  
Hepatocellular Carcinoma ◽  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Focal Lesion ◽  
Benign Lesions ◽  
Focal Lesions ◽  
Significant Difference ◽  
Apparent Diffusion ◽  
Malignant Lesions ◽  
The Mean

Abstract Background The aim of this study was to prospectively evaluate the role of diffusion weight MRI (DWI) in the characterization of hepatic focal lesions by using apparent diffusion coefficient (ADC). Thirty patients (18 women, 12 men; mean age 48.5 years) with hepatic focal lesions were included in this study. Patients underwent DW MR imaging with the SPLICE sequence. ADC of each focal lesion carcinoma was calculated from DW MR Images obtained with low and high b values. ADCs were compared among pathological types of focal lesions. Results Among the 30 patients included in the study, 46 focal lesions were detected. Twenty-four lesions were metastatic lesions from primary cancer, 7 lesions were hepatocellular carcinoma (HCC), 9 lesions were hemangiomas, and 6 lesions were simple cysts. There was highly significant difference between the mean ADC of the malignant lesions (metastasis and HCC) and the mean ADC of benign lesions (hemangiomas and cysts). The ADC of malignant lesion was much less than that of benign lesion. The mean ADC of malignant lesions (n = 31) was 0.73 ± 0.19 × 10−3 mm2/s, and the mean ADC of benign lesions (n = 15) was 1.94 ± 0.68 × 10−3 mm2/s (p value < 0.001). There was no significant difference between the cysts and hemangiomas. There was no statistically significant difference between the metastases and hepatocellular carcinoma. Conclusion ADCs values were able to differentiate benign from malignant lesions. ADC should be considered in the work up of patients with hepatic focal lesions.

scholarly journals Apparent Diffusion Coefficient Mapping Using a Multi-Shot Spiral MRI Sequence of the Rat Brain

2014 ◽  
Vol 04 (01) ◽  
pp. 13-24
Author(s):  
Tomokazu Numano ◽  
Koji Hyodo ◽  
Naotaka Nitta ◽  
Junichi Hata ◽  
Nobuaki Iwasaki ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Rat Brain ◽  
Apparent Diffusion ◽  
Spiral Mri ◽  
Apparent Diffusion Coefficient Mapping

scholarly journals Evaluating the Scope of Malignant Bone Tumor Using ADC Measurement on ADC Map

2019 ◽  
Vol 18 ◽  
pp. 153303381985326
Author(s):  
Haisong Chen ◽  
Zengjie Wu ◽  
Wenjian Xu ◽  
Jing Pang ◽  
Meng Jia ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Magnetic Resonance ◽  
Apparent Diffusion Coefficient ◽  
Bone Tumor ◽  
Malignant Bone Tumor ◽  
Apparent Diffusion Coefficient Value ◽  
Significant Difference ◽  
Apparent Diffusion ◽  
Vx2 Tumor ◽  
Apparent Diffusion Coefficient Mapping

Background: It is very important for surgeons to know the accurate borders of malignant bone tumors before they can precisely resect the tumors. The objective of the study is to investigate the usefulness of apparent diffusion coefficient value for estimating the extent of malignant bone tumor. Methods: VX2 tumor fragments were implanted into the tibiae of 30 rabbits. After 4 weeks, magnetic resonance plain scans were performed and then tumor specimens were cut into sagittal sections and partitioned into histology slices for dot-to-dot comparisons with microscopic findings. The sizes of the tumors measured separately on specimen, conventional magnetic resonance imaging sequences, and diffusion-weighted imaging (by measuring apparent diffusion coefficient value on apparent diffusion coefficient mapping) were compared statistically with each other. Results: The mean tumor sizes measured on specimen and apparent diffusion coefficient mapping (by calculating apparent diffusion coefficient value) were 5.20 ± 0.89 cm and 5.31 ± 0.87 cm, respectively; there was no significant difference between the 2 ( P > .05). The tumor sizes measured on T1WI, T2WI, T2WI with fat suppression were 4.82 ± 0.87 cm, 5.58 ± 0.87 cm, 5.63 ± 0.85 cm, respectively, and these values were significantly different from that measured on specimen (5.20 ± 0.89 cm, P < .05). Conclusion: The extent of the VX2 malignant bone tumor can be estimated accurately by measurement of apparent diffusion coefficient value.

scholarly journals Magnetic Resonance Diffusion W Imaging in Cerebral Fat Embolism

2004 ◽  
Vol 31 (3) ◽  
pp. 417-421 ◽  
Author(s):  
G.B. Marshall ◽  
V.R. Heale ◽  
L. Herx ◽  
A. Abdeen ◽  
L. Mrkonjic ◽  
...  
Keyword(s):  
Cell Death ◽  
Diffusion Coefficient ◽  
Magnetic Resonance ◽  
Apparent Diffusion Coefficient ◽  
Diffusion Weighted Imaging ◽  
Fat Embolism ◽  
Cytotoxic Edema ◽  
Apparent Diffusion ◽  
Weighted Sequences ◽  
Apparent Diffusion Coefficient Mapping

The use of diffusion weighted imaging with apparent diffusion coefficient mapping in the diagnosis of cerebral fat embolism is shown here to demonstrate infarcts secondary to fat emboli more intensely than T2 weighted sequences 24 hours after the onset of symptoms. Embolic foci are hypointense on apparent diffusion coefficient mapping consistent with cytotoxic edema associated with cell death and restricted water diffusion. This technique increases the sensitivity for detecting cerebral fat embolism and offers a potentially important tool in its diagnosis.

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